Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Angelika Rek"'
Autor:
Eszter Nagy, Andreas Meinke, Angelika Rek, Birgit Noiges, Alexander von Gabain, Daniela Schweiger, Andreas J. Kungl, Andrea Fritzer
Publikováno v:
Biochemical Journal. 422:533-542
Streptococcus pyogenes is one of the most common human pathogens and possesses diverse mechanisms to evade the human immune defence. One example of its immune evasion is the degradation of the chemokine IL (interleukin)-8 by ScpC, a serine proteinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edeef7bf39879b33c1b8ed9d79645a64
https://doi.org/10.1042/bj20090278
https://doi.org/10.1042/bj20090278
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1794:577-582
Binding of chemokines to glycosaminoglycans (GAGs) represents a crucial step in leukocyte attraction and activation. Since chemokine oligomerisation was shown to be important for GAG binding, the apparent oligomerisation constant of RANTES was determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1377d533fb377477fd498edcc6287b5e
https://doi.org/10.1016/j.bbapap.2009.01.001
https://doi.org/10.1016/j.bbapap.2009.01.001
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1774:72-77
K5 lyase of coliphage K5A degrades the K5 polysaccharide of encapsulated E. coli strains expressing the K5 antigen thereby contributing to virus binding and infection. We have investigated the affinities of the recombinant enzyme for different GAG li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb378f0f0ec90123e27c9cb1c23a6f66
https://doi.org/10.1016/j.bbapap.2006.10.017
https://doi.org/10.1016/j.bbapap.2006.10.017
Autor:
Werner Atzenhofer, Astrid Wabnig, Angelika Rek, Laszlo Szilak, Andreas J. Kungl, Yvonne Halden
Publikováno v:
Biochemical Journal. 377:533-538
Application of reverse transcription-PCR to total RNA prepared from TNF-alpha (tumour necrosis factor-alpha)-stimulated HUVECs (human umbilical vein endothelial cells) revealed that the syndecan-2 mRNA was up-regulated by this inflammatory stimulus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f470d4e453e0011f96d3f0d844caed2
https://doi.org/10.1042/bj20030729
https://doi.org/10.1042/bj20030729
Autor:
H. Potzinger, Barbara Brandner, Angelika Rek, Andreas J. Kungl, V. Wabitsch, Elena Geretti, Anna M. Piccinini
Publikováno v:
Biochemical Society Transactions. 34:435-437
The interaction of chemokines and GAGs (glycosaminoglycans) on endothelial surfaces is a crucial step for establishing a chemotactic gradient which leads to the functional presentation of chemokines to their GPCRs (G-protein-coupled receptors) and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83a510f7401e09ef4fc9701831dccba
https://doi.org/10.1042/bst0340435
https://doi.org/10.1042/bst0340435
Publikováno v:
C21. NEW TARGETS FOR ASTHMA THERAPY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da2b2038848003865d55054d085f7f6c
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4071
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4071
Autor:
Anna M. Piccinini, Gerhild Wildner, Angelika Rek, Andreas J. Kungl, Kerstin Knebl, Maria Diedrichs-Möhring
Leukocyte recruitment from the blood into injured tissues during inflammatory diseases is the result of sequential events involving chemokines binding to their GPC receptors as well as to their glycosaminoglycan (GAG) co-receptors. The induction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c352a01d3d6f278bca587890783562e6
https://europepmc.org/articles/PMC2838300/
https://europepmc.org/articles/PMC2838300/
Autor:
Christian Weber, Angelika Rek, Thomas Baltus, Andreas J. Kungl, Amanda E. I. Proudfoot, Peter J. Nelson, Stephan Segerer, Philipp von Hundelshausen, Zoë Johnson
Chemokine function in vivo depends on the presentation by structures of the extracellular matrix or on endothelial surfaces. CCL5 contains two clusters of basic amino acid residues ( 44 RKNR 47 and 55 KKWVR 59 ) implicated in presentation of the prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8875bf746429a2542a4b3f825ad8c31
https://www.zora.uzh.ch/id/eprint/28657/
https://www.zora.uzh.ch/id/eprint/28657/
Autor:
Andreas J. Kungl, Niklas Muenchmeier, Norbert Gretz, Eva Kiss, Carl Ludwig Behnes, Angelika Rek, Hermann Josef Gröne, Peter J. Nelson, Jens Bedke
Publikováno v:
Molecular immunology. 47(5)
Acute renal allograft damage is caused by early leukocyte infiltration which is mediated in part by chemokines presented by glycosaminoglycan (GAG) structures on endothelial surfaces. CXCL8 can recruit neutrophils and induce the firm arrest of monocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfede116e3591fcb18945aa418335761
https://pubmed.ncbi.nlm.nih.gov/20004976
https://pubmed.ncbi.nlm.nih.gov/20004976
Publikováno v:
Protein engineering, designselection : PEDS. 22(6)
Binding to glycosaminoglycans (GAGs) is a necessary prerequisite for the biological activity of the proinflammatory chemokine RANTES in vivo. We have applied protein engineering methods to modulate equilibrium-binding affinity as well as binding kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6aa3cb8c11c67993a95ac457fac999
https://pubmed.ncbi.nlm.nih.gov/19414521
https://pubmed.ncbi.nlm.nih.gov/19414521