Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Angelika, Pedal"'
Autor:
Florian Fuchs, Gregoire Pau, Dominique Kranz, Oleg Sklyar, Christoph Budjan, Sandra Steinbrink, Thomas Horn, Angelika Pedal, Wolfgang Huber, Michael Boutros
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)
Genetic screens for phenotypic similarity have made key contributions to associating genes with biological processes. With RNA interference (RNAi), highly parallel phenotyping of loss‐of‐function effects in cells has become feasible. One of the c
Externí odkaz:
https://doaj.org/article/136333f4d4ec4700b86f326a14b8ba5b
Autor:
Claudia Hetzer, Dwayne Bisgrove, Michael S Cohen, Angelika Pedal, Katrin Kaehlcke, Anja Speyerer, Kerstin Bartscherer, Jack Taunton, Melanie Ott
Publikováno v:
PLoS ONE, Vol 2, Iss 1, p e151 (2007)
The transcriptional activity of the integrated HIV provirus is dependent on the chromatin organization of the viral promoter and the transactivator Tat. Tat recruits the cellular pTEFb complex and interacts with several chromatin-modifying enzymes, i
Externí odkaz:
https://doaj.org/article/9d4ea5c3d3af4027bd7a869b69cb54b6
Autor:
Sara Pagans, Angelika Pedal, Brian J North, Katrin Kaehlcke, Brett L Marshall, Alexander Dorr, Claudia Hetzer-Egger, Peter Henklein, Roy Frye, Michael W McBurney, Henning Hruby, Manfred Jung, Eric Verdin, Melanie Ott
Publikováno v:
PLoS Biology, Vol 3, Iss 2, p e41 (2005)
The human immunodeficiency virus (HIV) Tat protein is acetylated by the transcriptional coactivator p300, a necessary step in Tat-mediated transactivation. We report here that Tat is deacetylated by human sirtuin 1 (SIRT1), a nicotinamide adenine din
Externí odkaz:
https://doaj.org/article/1f4e87794ef5457ca7e901e53e2cc8de
Autor:
Oleg Sklyar, Gregoire Pau, Angelika Pedal, Dominique Kranz, Thomas Horn, Michael Boutros, Florian Fuchs, Wolfgang Huber, Christoph Budjan, Sandra Steinbrink
Publikováno v:
Molecular Systems Biology
How to predict gene function from phenotypic cues is a longstanding question in biology. Using quantitative multiparametric imaging, RNAi-mediated cell phenotypes were measured on a genome-wide scale. On the basis of phenotypic ‘neighbourhoods', we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574155f8c5f1fdad17e178a797f0a002
https://doi.org/10.1038/msb.2010.25
https://doi.org/10.1038/msb.2010.25
Autor:
Katrin Kaehlcke, Sebastian Schroeder, Hye-Sook Kwon, Sungyoo Cho, Martina Schnoelzer, Melanie Ott, Angelika Pedal, Eva Herker
The elongation competence of the RNA polymerase II complex is critically dependent on the positive transcription elongation factor b (P-TEFb). P-TEFb exists in two forms in cells, an active form composed of cyclin T1 and CDK9 and an inactive form, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5434b1e5629fee3926da5cff29e40c
https://europepmc.org/articles/PMC2688543/
https://europepmc.org/articles/PMC2688543/
Autor:
Dwayne Bisgrove, Angelika Pedal, Claudia Hetzer, Katrin Kaehlcke, Michael S. Cohen, Melanie Ott, Anja Speyerer, Kerstin Bartscherer, Jack Taunton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 2, Iss 1, p e151 (2007)
PLoS ONE, Vol 2, Iss 1, p e151 (2007)
The transcriptional activity of the integrated HIV provirus is dependent on the chromatin organization of the viral promoter and the transactivator Tat. Tat recruits the cellular pTEFb complex and interacts with several chromatin-modifying enzymes, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413cfe5b6967b8d9bd1ed2eefe3bd38f
http://europepmc.org/articles/PMC1764712
http://europepmc.org/articles/PMC1764712
Autor:
Brian J. North, Michael W. McBurney, Roy A. Frye, Angelika Pedal, Peter Henklein, Katrin Kaehlcke, Sara Pagans, Henning Hruby, Alexander Dorr, Claudia Hetzer-Egger, Brett Marshall, Melanie Ott, Eric Verdin, Manfred Jung
Publikováno v:
PLoS Biology, Vol 3, Iss 2, p e41 (2005)
Scopus-Elsevier
Scopus-Elsevier
The human immunodeficiency virus (HIV) Tat protein is acetylated by the transcriptional coactivator p300, a necessary step in Tat-mediated transactivation. We report here that Tat is deacetylated by human sirtuin 1 (SIRT1), a nicotinamide adenine din
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b905ecc4bfc5d46b801b6c95e69643b
http://europepmc.org/articles/PMC546329?pdf=render
http://europepmc.org/articles/PMC546329?pdf=render
Autor:
Sara, Pagans, Angelika, Pedal, Brian J, North, Katrin, Kaehlcke, Brett L, Marshall, Alexander, Dorr, Claudia, Hetzer-Egger, Peter, Henklein, Roy, Frye, Michael W, McBurney, Henning, Hruby, Manfred, Jung, Eric, Verdin, Melanie, Ott
Publikováno v:
PLoS Biology
The human immunodeficiency virus (HIV) Tat protein is acetylated by the transcriptional coactivator p300, a necessary step in Tat-mediated transactivation. We report here that Tat is deacetylated by human sirtuin 1 (SIRT1), a nicotinamide adenine din
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::941058bf84695634a64bbb14e77dfc93
https://pubmed.ncbi.nlm.nih.gov/15719057
https://pubmed.ncbi.nlm.nih.gov/15719057
Autor:
Angelika Pedal, Vaclav Horejsi, Jürgen Kartenbeck, Benedikt Fritzsching, Björn Schwer, Melanie Ott
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(10)
The human tetraspan molecule CD81 is a coreceptor in B and T cell activation and a candidate receptor for hepatitis C virus infection. We examined the surface expression of CD81 on B and T lymphocytes by quantitative flow cytometry. Upon cellular act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ba389e7e4c91221503735c100ca8b8
https://pubmed.ncbi.nlm.nih.gov/12421929
https://pubmed.ncbi.nlm.nih.gov/12421929
Autor:
Veronique Kiermer, Angelika Pedal, Hans-Richard Rackwitz, Ming-Ming Zhou, Melanie Ott, Eric Verdin, Ulrich Schubert, Alexander Dorr, Peter Henklein
Publikováno v:
The EMBO journal. 21(11)
The human immunodeficiency virus (HIV) Tat protein plays an essential role in promoting efficient transcriptional elongation of viral transcripts. We report that the transcriptional co-activator PCAF and Tat interact and synergize to activate the HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d58b7df962f290fc7017af29d39d754
https://pubmed.ncbi.nlm.nih.gov/12032084
https://pubmed.ncbi.nlm.nih.gov/12032084