Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Angelico D"'
Autor:
Maria George Elias, Angelico D. Aputen, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8252 (2024)
Chlorambucil-platinum(IV) prodrugs exhibit multi-mechanistic chemotherapeutic activity with promising anticancer potential. The platinum(II) precursors of the prodrugs have been previously found to induce changes in the microtubule cytoskeleton, spec
Externí odkaz:
https://doaj.org/article/2b4798a84a594134bd63ed251d1b3839
Autor:
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2181 (2024)
Kinetically inert platinum(IV) complexes are a chemical strategy to overcome the impediments of standard platinum(II) antineoplastic drugs like cisplatin, oxaliplatin and carboplatin. In this study, we reported the syntheses and structural characteri
Externí odkaz:
https://doaj.org/article/895f80b1275247969fe711f6d4a6beef
Autor:
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
Molecules, Vol 27, Iss 20, p 7120 (2022)
A new series of cytotoxic platinum(IV) complexes (1–8) incorporating halogenated phenylacetic acid derivatives (4-chlorophenylacetic acid, 4-fluorophenylacetic acid, 4-bromophenylacetic acid and 4-iodophenylacetic acid) were synthesised and charact
Externí odkaz:
https://doaj.org/article/c9af94e27190424db7547603cd8e96f5
Autor:
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10471 (2022)
The DNA-alkylating derivative chlorambucil was coordinated in the axial position to atypical cytotoxic, heterocyclic, and non-DNA coordinating platinum(IV) complexes of type, [PtIV(HL)(AL)(OH)2](NO3)2 (where HL is 1,10-phenanthroline, 5-methyl-1,10-p
Externí odkaz:
https://doaj.org/article/0e8d8ac6cdd448829b6049a002158c29
Autor:
Elias, Maria George1,2 (AUTHOR) m.elias3@westernsydney.edu.au, Aputen, Angelico D.1 (AUTHOR) a.aputen@westernsydney.edu.au, Fatima, Shadma2,3 (AUTHOR) tim.mann@unsw.edu.au, Mann, Timothy J.2,3 (AUTHOR) kieran.scott@westernsydney.edu.au, Karan, Shawan1 (AUTHOR) shawan.karan@westernsydney.edu.au, Mikhael, Meena4 (AUTHOR) m.mikhael@westernsydney.edu.au, de Souza, Paul5 (AUTHOR) paul.desouza@sydney.edu.au, Gordon, Christopher P.1 (AUTHOR) c.gordon@westernsydney.edu.au, Scott, Kieran F.2,3 (AUTHOR), Aldrich-Wright, Janice R.1,2 (AUTHOR) j.aldrich-wright@westernsydney.edu.au
Publikováno v:
International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8252. 38p.
Autor:
Aputen, Angelico D.1 (AUTHOR) a.aputen@westernsydney.edu.au, Elias, Maria George1,2 (AUTHOR) kieran.scott@westernsydney.edu.au, Gilbert, Jayne3 (AUTHOR) jayne.gilbert@newcastle.edu.au, Sakoff, Jennette A.3 (AUTHOR) jennette.sakoff@newcastle.edu.au, Gordon, Christopher P.1 (AUTHOR) c.gordon@westernsydney.edu.au, Scott, Kieran F.2,4 (AUTHOR), Aldrich-Wright, Janice R.1 (AUTHOR) j.aldrich-wright@westernsydney.edu.au
Publikováno v:
International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 4, p2181. 33p.
Autor:
Aputen, Angelico D.1 (AUTHOR) a.aputen@westernsydney.edu.au, Elias, Maria George1,2 (AUTHOR) m.elias3@westernsydney.edu.au, Gilbert, Jayne3 (AUTHOR), Sakoff, Jennette A.3 (AUTHOR), Gordon, Christopher P.1 (AUTHOR), Scott, Kieran F.2,4 (AUTHOR), Aldrich-Wright, Janice R.1 (AUTHOR) j.aldrich-wright@westernsydney.edu.au
Publikováno v:
Cancers. May2023, Vol. 15 Issue 9, p2460. 34p.
Autor:
Aputen, Angelico D.1 (AUTHOR), Elias, Maria George1,2 (AUTHOR), Gilbert, Jayne3 (AUTHOR), Sakoff, Jennette A.3 (AUTHOR), Gordon, Christopher P.1 (AUTHOR), Scott, Kieran F.2 (AUTHOR), Aldrich-Wright, Janice R.1 (AUTHOR) j.aldrich-wright@westernsydney.edu.au
Publikováno v:
Molecules. Oct2022, Vol. 27 Issue 20, p7120-N.PAG. 36p.
Autor:
Aputen, Angelico D.1 (AUTHOR), Elias, Maria George1,2 (AUTHOR), Gilbert, Jayne3 (AUTHOR), Sakoff, Jennette A.3 (AUTHOR), Gordon, Christopher P.1 (AUTHOR), Scott, Kieran F.2 (AUTHOR), Aldrich-Wright, Janice R.1 (AUTHOR) j.aldrich-wright@westernsydney.edu.au
Publikováno v:
International Journal of Molecular Sciences. Sep2022, Vol. 23 Issue 18, pN.PAG-N.PAG. 28p.
Autor:
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2460
Developing new and versatile platinum(IV) complexes that incorporate bioactive moieties is a rapidly evolving research strategy for cancer drug discovery. In this study, six platinum(IV) complexes (1–6) that are mono-substituted in the axial positi