Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Angelica Sandoval-Perez"'
Autor:
Paul J. Sampognaro, Shruti Arya, Giselle M. Knudsen, Emma L. Gunderson, Angelica Sandoval-Perez, Molly Hodul, Kathryn Bowles, Charles S. Craik, Matthew P. Jacobson, Aimee W. Kao
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background Autosomal dominant mutations in α-synuclein, TDP-43 and tau are thought to predispose to neurodegeneration by enhancing protein aggregation. While a subset of α-synuclein, TDP-43 and tau mutations has been shown to increase the
Externí odkaz:
https://doaj.org/article/e9dcb181060f4b0d9dcfbc703faec0a4
Autor:
Paul J. Sampognaro, Shruti Arya, Giselle M. Knudsen, Emma L. Gunderson, Angelica Sandoval-Perez, Molly Hodul, Kathryn Bowles, Charles S. Craik, Matthew P. Jacobson, Aimee W. Kao
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/54f456d00d3341bd985157eb4b460991
Autor:
Diego Garrido Ruiz, Angelica Sandoval-Perez, Amith Vikram Rangarajan, Emma L. Gunderson, Matthew P. Jacobson
Publikováno v:
Biochemistry, vol 61, iss 20
Cysteine side chains can exist in distinct oxidation states depending on the pH and redox potential of the environment, and cysteine oxidation plays important yet complex regulatory roles. Compared with the effects of post-translational modifications
Autor:
Aimee Kao, Paul Sampognaro, Shruti Arya, Giselle Knudsen, Emma Gunderson, Angelica Sandoval-Perez, Charles Craik, Matthew Jacobson
Autosomal dominant mutations in α-synuclein, TDP-43 and tau promote protein aggregation and neurodegeneration. Rates of aggregation are highly dependent on protein concentration, which can be regulated via lysosomal proteolysis. Lysosomal cathepsins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791c2df8111f20885e31180c6530a092
https://doi.org/10.21203/rs.3.rs-1451319/v1
https://doi.org/10.21203/rs.3.rs-1451319/v1
Autor:
Adiran Garaizar, Volker Huck, Joachim O. Rädler, Stefan W. Schneider, Maria A. Brehm, Angelica Sandoval-Perez, Gesa König, Stephen E. Farr, Ricarda M L Berger, Rosana Collepardo-Guevara, Camilo Aponte-Santamaría
Publikováno v:
Nucleic Acids Research
Neutrophils release their intracellular content, DNA included, into the bloodstream to form neutrophil extracellular traps (NETs) that confine and kill circulating pathogens. The mechanosensitive adhesive blood protein, von Willebrand Factor (vWF), i
Autor:
Irmgard Sinning, Rainer D. Beck, Camilo Aponte-Santamaría, Britta Brügger, Markus Kurth, Fabio Lolicato, Angelica Sandoval-Perez, Alexandra Teslenko, Helman Amaya-Espinosa
Publikováno v:
The journal of physical chemistry. B. 124(41)
The metabotropic glutamate receptor (mGluR) 2 plays a key role in the central nervous system. mGluR2 has been shown to be regulated by its surrounding lipid environment, especially by cholesterol, by an unknown mechanism. Here, using a combination of
Autor:
Angelica Sandoval-Perez
Publikováno v:
Biophysical Journal. 118:212a
Publikováno v:
Journal of chemical theory and computation. 13(5)
Molecular dynamics (MD) simulations offer the possibility to study biological processes at high spatial and temporal resolution often not reachable by experiments. Corresponding biomolecular force field parameters have been developed for a wide varie
Publikováno v:
Biophysical Journal. 116:215a
Autor:
Diana Vanegas, David Becerra, Fernando Nino, Angelica Sandoval-Perez, Daniel Restrepo-Montoya
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783642372063
EuroGP
EuroGP
This work proposes a multi-objective algorithmic method for modelling the prediction of the conformation and configuration of ligands in receptor-ligand complexes by considering energy contributions of molecular interactions. The proposed approach is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49253fe2692c4c8aa80c6570fd065641
https://doi.org/10.1007/978-3-642-37207-0_16
https://doi.org/10.1007/978-3-642-37207-0_16