Výsledky vyhledávání - "Angelica Milik"

Fr141 COMBINATION OF FXR AGONIST MET642 WITH TOFACITINIB EXHIBITS SYNERGISTIC EFFECTS IN IMPROVING COLITIS IN ADOPTIVE T-CELL TRANSFER IBD MODEL

Autor: Robert O'Connell, Julie White, Xueqing Liu, Brent E. Palmer, Angelica Milik, Brandee Wagner, Sharon Sen

Publikováno v: Gastroenterology. 160:S-236

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a05a99a802ca3bbaebf05eb4cd0e74a
https://doi.org/10.1016/s0016-5085(21)01304-4

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767 ACTIVATION OF FXR SUPPRESSES TNFA AND IL-6 SIGNALING PATHWAYS AND IMPROVES COLITIS IN TWO CHRONIC MOUSE MODELS OF IBD

Publikováno v: Gastroenterology. 158:S-159

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfd2a2f4e9195c6ac1fb4639f528d2e2
https://doi.org/10.1016/s0016-5085(20)31085-4

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P153 MET642, AN ORAL FXR AGONIST, IMPROVES COLITIS INDUCED BY ADOPTIVE T-CELL TRANSFER

Autor: Kyoung-Jin Lee, Douglas Zook, Johnny Y. Nagasawa, Angelica Milik, Steve Govek, Pauline Chai, Brandee Wagner, Ken Song, Robert O'Connell, Connor Ohlsen, Xueqing Liu, Jing Qian, Karensa L. Douglas, Alison M. Bendele, Alvaro Ortiz, Nicholas R. Smith, Nhin Lu, Melissa Walker

Publikováno v: Gastroenterology. 158:S11

Introduction Farnesoid X receptor (FXR) is a ligand-activated nuclear hormone receptor expressed in the gastrointestinal tract, with high expression levels in the intestinal epithelium. Previously we have shown that FXR agonists with sustained activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9b8bf53719b800993a7caa2379e813
https://doi.org/10.1053/j.gastro.2019.11.062

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Sa1737 – Fxr Agonist M480, Exhibits Efficacy in Multiple Models of Inflammatory Bowel Disease (IBD) by Increasing Expression of Anti-Microbial Genes and Reducing Inflammatory Cytokine Expression in the Gut

Autor: Kyoung-Jin Lee, Hubert Chen, Robert O'Connell, Jing Qian, Nhin Lu, Harry Dedman, Connor Ohlsen, Karensa L. Douglas, Alison M. Bendele, Alvaro Ortiz, Joshua D. Boyer, Nicholas R. Smith, Steve Govek, Xueqing Liu, Brandee Wagner, Ken Song, Johnny Y. Nagasawa, Angelica Milik

Publikováno v: Gastroenterology. 156:S-382

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81cee33b10bd08d013f84d04dbb5f121
https://doi.org/10.1016/s0016-5085(19)37804-7

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Sa1747 – Fxr Agonists with Sustained Activity Exhibit Efficacy Comparable to Anti-Il-12P40 in Treating Colitis Induced by Adoptive T-Cell Transfer

Autor: Brandee Wagner, Ken Song, Steve Govek, Connor Ohlsen, Kyoung-Jin Lee, Hubert Chen, Karensa L. Douglas, Alison M. Bendele, Robert O'Connell, Jing Qian, Nicholas R. Smith, Alvaro Ortiz, Nhin Lu, Johnny Y. Nagasawa, Angelica Milik, Xueqing Liu, Harry Dedman

Publikováno v: Gastroenterology. 156:S-385

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd2aed99df52ce18379451109db8ebd3
https://doi.org/10.1016/s0016-5085(19)37814-x

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1051 - M480, an Oral Fxr Agonist, is Superior to Cyclosporine a and Equally Efficacious as Anti-Il-12/23 in the Adoptive Transfer Model of IBD Colitis

Autor: Kyoung-Jin Lee, Nhin Lu, Johnny Y. Nagasawa, Alvaro Ortiz, Angelica Milik, Harry Dedman, Connor Ohlsen, Robert O'Connell, Karensa L. Douglas, Alison M. Bendele, Xueqing Liu, Jing Qian, Nicholas R. Smith, Brandee Wagner, Ken Song, Steve Govek

Publikováno v: Gastroenterology. 154:S-198

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa134f5e17244d02f1f356e54a97e3c9
https://doi.org/10.1016/s0016-5085(18)31066-7

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