Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Angelica M. Gutierrez-Barrera"'
Autor:
Haven R. Garber, Akshara Singareeka Raghavendra, Michael Lehner, Wei Qiao, Angelica M. Gutierrez-Barrera, Debu Tripathy, Banu Arun, Nuhad K. Ibrahim
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Patients with hereditary mutations in BRCA1 or BRCA2 (gBRCA1/2) and breast cancer have distinct tumor biology, and encompass a predilection for brain metastasis (BM). We looked into baseline risk of BMs among gBRCA1/2 patients. Patients with
Externí odkaz:
https://doaj.org/article/f030913dffdd4ede9b5d864d22d62e01
Autor:
Rachel M. Layman, Heather Lin, Angelica M. Gutierrez Barrera, Meghan S. Karuturi, Clinton Yam, Banu K. Arun
Publikováno v:
Cancer Medicine, Vol 11, Iss 6, Pp 1474-1483 (2022)
Abstract Background BRCA‐associated breast cancers tend to have distinctive features compared to sporadic breast cancers; further characterization can aid in optimizing treatment. Methods The study evaluated a patient cohort with early‐stage estr
Externí odkaz:
https://doaj.org/article/d4ac527a527d4079b8d553509d3f7582
Autor:
Sukh Makhnoon, Angelica M. Gutierrez Barrera, Roland Bassett, Aimaz Afrough, Isabelle Bedrosian, Banu K. Arun
Publikováno v:
The Breast Journal, Vol 2022 (2022)
Background. Patients with unilateral breast cancer carrying pathogenic variants in BRCA1/2 have the option to undergo contralateral prophylactic mastectomy (CPM). However, differences in CPM use and survival outcomes following CPM are poorly understo
Externí odkaz:
https://doaj.org/article/a6b0af19cfa14ba8a1c4881337746306
Autor:
Brittany L. Murphy, Min Yi, Angelica M. Gutierrez Barrera, Debu Tripathy, Kelly K. Hunt, Banu K. Arun
Publikováno v:
Annals of Surgical Oncology. 30:1663-1668
Outcomes After Breast Radiation Therapy in a Diverse Patient Cohort With a Germline BRCA1/2 Mutation
Autor:
Jennifer K. Litton, Isabelle Bedrosian, Bhavana V. Chapman, Shane R. Stecklein, Michael C. Stauder, Yu Shen, Eric A. Strom, David S. Lakomy, George H. Perkins, Karen E. Hoffman, Scott J. Bright, Simona F. Shaitelman, Wendy A. Woodward, Angelica M. Gutierrez Barrera, Gabriel O. Sawakuchi, Banu Arun, Oluwafikayo O. Olamigoke, Diane Liu, Benjamin Smith
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose BRCA1/2 pathogenic variant (PV) mutations confer radiation sensitivity preclinically, but there are limited data regarding breast cancer outcomes after radiation therapy (RT) among patients with documented BRCA1/2 PV mutations versus no PV mu
Autor:
Toma S. Omofoye, Huong T. Le-Petross, Niloofar Karbasian, Constance Albarracin, Angelica M. Gutierrez-Barrera, Sahand Sohrabi, Banu Arun, Kenneth R. Hess, Gary J. Whitman
Publikováno v:
Curr Probl Diagn Radiol
Objective: The purpose of this study is to review the mammographic and the ultrasound features of triple negative breast cancer (TNBC) patients and to investigate the potential effect of BRCA mutations on the imaging features of these patients. Metho
Autor:
Asha S. Multani, Haowei Du, Michael D. Nicholson, Tom O. McDonald, Hanghui Ye, Toby Baker, Emi Sei, Funda Meric-Bernstam, Franziska Michor, Jin Ma, Shanshan Bai, Banu Arun, Maxime Tarabichi, Angelica M. Gutierrez Barrera, Aislyn Schalck, Mashiat Rabbani, Anna Casasent, Peter Van Loo, Nicholas Navin, Bora Lim, Alexander Davis, Cheng Peng, Yu-wei Lin, Kaile Wang, Min Hu, Darlan Conterno Minussi, Hui Chen
Publikováno v:
Nature
Our knowledge of copy number evolution during the expansion of primary breast tumours is limited1,2. Here, to investigate this process, we developed a single-cell, single-molecule DNA-sequencing method and performed copy number analysis of 16,178 sin
Publikováno v:
Cancer Research. 81:PS8-28
Background: Women with germline mutations in the BRCA1 or BRCA2 (BRCA1/2) genes have a significantly increased lifetime risk of developing breast and ovarian cancers. Since approximately 5-10% of breast and ovarian cancer is due to a hereditary predi
Autor:
Stephen K. Gruschkus, Rashmi Krishna Murthy, Angelica M. Gutierrez Barrera, Mihir A Shukla, Banu Arun, Rachel M. Layman
Publikováno v:
Cancer Research. 81:PS4-31
Introduction: Breast cancer in BRCA 1/2 carriers is a well-characterized disease process, and its association with triple negative breast cancer has been extensively studied. In contrast, there is limited data on BRCA carriers and HER2/neu positive b
Autor:
Nam H. Nguyen, Elissa B. Dodd-Eaton, Jessica L. Corredor, Jacynda Woodman-Ross, Nathaniel D. Hernandez, Angelica M. Gutierrez Barrera, Banu K. Arun, Wenyi Wang
Publikováno v:
Cancer Research. 83:5240-5240
Age-at-onset penetrance is the probability of developing disease by a certain age given a patient’s characteristics. Accurate penetrance estimates are important for cancer screening and diagnosis, and for policy making in public health. We develope