Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Angelica Lin"'
Autor:
Erik R. Peterson, Peter Sajjakulnukit, Andrew J. Scott, Caleb Heaslip, Anthony Andren, Kari Wilder-Romans, Weihua Zhou, Sravya Palavalasa, Navyateja Korimerla, Angelica Lin, Alexandra O’Brien, Ayesha Kothari, Zitong Zhao, Li Zhang, Meredith A. Morgan, Sriram Venneti, Carl Koschmann, Nada Jabado, Costas A. Lyssiotis, Maria G. Castro, Daniel R. Wahl
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Background Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine 27 to methionine (H3K27M). DMG-H3K27M
Externí odkaz:
https://doaj.org/article/1951e061c7ab4540990fd8c2ffa35723
Autor:
Weihua Zhou, Zitong Zhao, Angelica Lin, John Yang, Jie Xu, Wilder-Romans Kari, Annabel Yang, Jing Li, Sumeet Solanki, Jennifer Speth, Natalie Walker, Andrew J. Scott, Ayesha U. Kothari, Yangyang Yao, Erik R. Peterson, Navyateja Korimerla, Christian K. Werner, Jessica Liang, Janna Jacobson, Sravya Palavalasa, Alexandra M. Obrien, Ameer L. Elaimy, Sean P. Ferris, Shuang G. Zhao, Jann N. Sarkaria, Balázs Győrffy, Shuqun Zhang, Wajd N Al-Holou, Yoshie Umemura, Meredith A. Morgan, Theodore S. Lawrence, Costas A. Lyssiotis, Marc Peters-Golden, Yatrik M. Shah, Daniel R. Wahl
Publikováno v:
bioRxiv
How cell metabolism regulates DNA repair is incompletely understood. Here, we define a GTP-mediated signaling cascade that links metabolism to DNA repair and has significant therapeutic implications. GTP, but not other nucleotides, regulates the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47dac35ff3bc7bc06b90f06a038189a
https://europepmc.org/articles/PMC10120670/
https://europepmc.org/articles/PMC10120670/
Autor:
Aled Daffyd Rees, Deborah P Merke, Wiebke Arlt, Aude Brac De La Perriere, Angelica Linden-Hirschberg, Anders Juul, John Newell-Price, Alessandro Prete, Nicole Reisch, Nike M Stikkelbroeck, Philippe A Touraine, Alex Lewis, John Porter, Helen Coope, Richard J Ross
Publikováno v:
Endocrine Connections, Vol 13, Iss 8, Pp 1-8 (2024)
Background: Prednisolone and prednisone are recommended treatment options for adults with congenital adrenal hyperplasia (CAH); however, there is no randomised comparison of prednis(ol)one with hydrocortisone. Design: Six-month open-label randomised
Externí odkaz:
https://doaj.org/article/9c082fbf1ccd444a90aea6c8d0fd6b11
Autor:
Weihua Zhou, Angelica Lin, Zitong Zhao, John Yang, Kari Wilder-Romans, Jie Xu, Sumeet Solanki, Jing Li, Annabel Yang, Andrew Scott, Ayesha Kothari, Erik Peterson, Navyateja Korimerla, Jessica Liang, Janna Jacobson, Sravya Palavalasa, Alexandra Obrien, Sean Ferris, Shuang Zhao, Jann N. Sarkaria, Meredith Morgan, Theodore S. Lawrence, Costas A. Lyssiotis, Yatrik Shah, Daniel R. Wahl
Publikováno v:
Cancer Research. 83:3498-3498
Introduction/Objectives: Purines regulate DNA repair in brain tumors through uncertain mechanisms. We sought to define the mechanisms by which purines regulate DNA repair and therapy response. Methods: Crispr/Cas9, siRNA, and CDNA overexpression and
Publikováno v:
BJPsych Open, Vol 10, Pp S177-S177 (2024)
Aims Menopausal symptoms often go unrecognised in individuals with intellectual disability (ID). There is growing societal awareness of the impact of menopause on mental health, yet this has not been replicated in the ID population. In light of this,
Externí odkaz:
https://doaj.org/article/11234bf5ab404b3b9de12bcf29a9a1aa
Autor:
Anastasia Trouva, Michael Alvarsson, Jan Calissendorff, Bjørn Olav Åsvold, Dorina Ujvari, Angelica Lindén Hirschberg, Eszter Vanky
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
ObjectivesPolycystic ovary syndrome (PCOS) and thyroid disorders have both been linked to adverse pregnancy and neonatal outcomes. Even small variations in thyroid function within the normal range may influence fetal growth. Our aim was to investigat
Externí odkaz:
https://doaj.org/article/301617e0ad044d15b34a03bd732ce9b2
Autor:
Linda Ekenros, Philip von Rosen, Jessica Norrbom, Hans-Christer Holmberg, Carl Johan Sundberg, Cecilia Fridén, Angelica Lindén Hirschberg
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background The menstrual cycle and its impact on training and performance are of growing interest. However, evidence is lacking whether periodized exercise based on the menstrual cycle is beneficial. The primary purpose of this proposed rand
Externí odkaz:
https://doaj.org/article/fc18f788544843ad9c53efa76653c713
Autor:
Neda Rajamand Ekberg, Anton Hellberg, Michaela Linn Sundqvist, Angelica Lindén Hirschberg, Sergiu-Bogdan Catrina, Kerstin Brismar
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9731 (2024)
This non-randomized controlled trial aimed to compare the effect of the 5:2 diet on insulin levels as a primary outcome and markers of insulin secretion (connecting peptide (C-peptide) and insulin-like growth factor binding protein-1 (IGFBP-1)) and s
Externí odkaz:
https://doaj.org/article/df0468144bf340beb1882c010a4ba53f
Autor:
Hanna Björlin Avdic, Claes Strannegård, Hedvig Engberg, Charlotte Willfors, Ida Nordgren, Louise Frisén, Angelica Lindén Hirschberg, Mona Guath, Ann Nordgren, Johan Lundin Kleberg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Turner syndrome is a genetic condition caused by a complete or partial loss of one of the X chromosomes. Previous studies indicate that Turner syndrome is associated with challenges in social skills, but the underlying mechanisms remain larg
Externí odkaz:
https://doaj.org/article/3a471176cc094b27a8ceb37afa52cfed
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Objective Serum prokineticin-1 (s-PROK1) in the second and third trimester of pregnancy is positively correlated to preeclampsia, intrauterine growth restriction (IUGR) and preterm delivery. Women with polycystic ovary syndrome (PCOS) are prone to th
Externí odkaz:
https://doaj.org/article/6616a9073589480dbc8b57263048e27e