Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Angelica Liechti"'
Autor:
Hima Priyanka Nadimpalli, Georgia Katsioudi, Enes Salih Arpa, Lies Chikhaoui, Alaaddin Bulak Arpat, Angelica Liechti, Gaël Palais, Claudia Tessmer, Ilse Hofmann, Bruno Galy, David Gatfield
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Background Cellular iron homeostasis is regulated by iron regulatory proteins (IRP1 and IRP2) that sense iron levels (and other metabolic cues) and modulate mRNA translation or stability via interaction with iron regulatory elements (IREs).
Externí odkaz:
https://doaj.org/article/adbd80f2d6ec4f649e63fe30ae6f1eef
Autor:
Georgia Katsioudi, René Dreos, Enes S. Arpa, Sevasti Gaspari, Angelica Liechti, Miho Sato, Christian H. Gabriel, Achim Kramer, Steven A. Brown, David Gatfield
Publikováno v:
Science Advances. 9
Nonsense-mediated messenger RNA (mRNA) decay (NMD) has been intensively studied as a surveillance pathway that degrades erroneous transcripts arising from mutations or RNA processing errors. While additional roles in physiological control of mRNA sta
Autor:
Moritz Schaefer, Amena Nabih, Daniel Spies, Victoria Hermes, Maxime Bodak, Harry Wischnewski, Patrick Stalder, Richard Patryk Ngondo, Luz Angelica Liechti, Tatjana Sajic, Ruedi Aebersold, David Gatfield, Constance Ciaudo
Publikováno v:
EMBO Reports, 23 (9)
EMBO reports, vol. 23, no. 9, pp. e54762
EMBO reports, vol. 23, no. 9, pp. e54762
MicroRNA (miRNA) loaded Argonaute (AGO) complexes regulate gene expression via direct base pairing with their mRNA targets. Previous works suggest that up to 60% of mammalian transcripts might be subject to miRNA-mediated regulation, but it remains l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac6c06db06c71b93a726d1891fff63a
https://hdl.handle.net/20.500.11850/561780
https://hdl.handle.net/20.500.11850/561780
Autor:
Richard Patryk Ngondo, David Gatfield, Amena Nabih, Tatjana Sajic, Constance Ciaudo, Luz Angelica Liechti, Daniel Spies, Ruedi Aebersold, Patrick Stalder, Maxime Bodak, Harry Wischnewski, Moritz Schaefer
SUMMARYMicroRNA (miRNA) loaded Argonaute (AGO) complexes regulate gene expression via direct base pairing with their mRNA targets. Current prediction approaches identified that between 20 to 60% of mammalian transcriptomes are regulated by miRNAs, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b1c62e4561143e4e8a195f85bd668eb
https://doi.org/10.1101/2021.09.24.461622
https://doi.org/10.1101/2021.09.24.461622
Autor:
Daniel Hess, Marc Bühler, David Gatfield, Alaaddin Bulak Arpat, Aneliya Rankova, Vytautas Iesmantavicius, Luz Angelica Liechti, Violeta Castelo-Szekely, Alex Tuck
Publikováno v:
Molecular Cell
Summary RNA decay is crucial for mRNA turnover and surveillance and misregulated in many diseases. This complex system is challenging to study, particularly in mammals, where it remains unclear whether decay pathways perform specialized versus redund
Autor:
Sophie Roy, Luz Angelica Liechti, Stephan Kellenberger, Simon Bernèche, Justyna Iwaszkiewicz, Olivier Michielin, Benoîte Bargeton
Publikováno v:
Journal of Biological Chemistry, vol. 285, no. 21, pp. 16315-16329
J Biol Chem
J Biol Chem
Acid-sensing ion channels (ASICs) are key receptors for extracellular protons. These neuronal nonvoltage-gated Na(+) channels are involved in learning, the expression of fear, neurodegeneration after ischemia, and pain sensation. We have applied a sy
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional d
Externí odkaz:
https://doaj.org/article/01df0f7d13964ee1b3ec70ae5ce9cc3a
Autor:
Philippe Julien, David Brawand, Magali Soumillon, Anamaria Necsulea, Angélica Liechti, Frédéric Schütz, Tasman Daish, Frank Grützner, Henrik Kaessmann
Publikováno v:
PLoS Biology, Vol 10, Iss 5, p e1001328 (2012)
As a result of sex chromosome differentiation from ancestral autosomes, male mammalian cells only contain one X chromosome. It has long been hypothesized that X-linked gene expression levels have become doubled in males to restore the original transc
Externí odkaz:
https://doaj.org/article/007f994e7b2f422da2a2f5367fe104bc