Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Angelica K. Gierut"'
Autor:
Alexander V. Misharin, Carla M. Cuda, Rana Saber, Jason D. Turner, Angelica K. Gierut, G. Kenneth Haines III, Sergejs Berdnikovs, Andrew Filer, Andrew R. Clark, Christopher D. Buckley, Gökhan M. Mutlu, G.R. Scott Budinger, Harris Perlman
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 591-604 (2014)
Different subsets and/or polarized phenotypes of monocytes and macrophages may play distinct roles during the development and resolution of inflammation. Here, we demonstrate in a murine model of rheumatoid arthritis that nonclassical Ly6C− monocyt
Externí odkaz:
https://doaj.org/article/5f76a3ed4772478ea981cc4cf21d01b1
Publikováno v:
Rheumatic Disease Clinics of North America. 36:271-296
Innate immunity, with macrophages playing a central role, is critically important in the pathogenesis of RA. Although environmental insults such as smoking have been implicated in the initiation of rheumatoid arthritis (RA) in patients who express th
Autor:
Rana Saber, G. R. Scott Budinger, Harris Perlman, Chandra Mohan, Carla M. Cuda, Jack Hutcheson, Christian Stehlik, Alexander V. Misharin, Stephen M. Hedrick, G. Kenneth Haines, Angelica K. Gierut
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(12)
Caspase-8, an executioner enzyme in the death receptor pathway, was shown to initiate apoptosis and suppress necroptosis. In this study, we identify a novel, cell death–independent role for caspase-8 in dendritic cells (DCs): DC-specific expression
Publikováno v:
Frontiers in Neurology, Vol 5 (2014)
Frontiers in Neurology
Frontiers in Neurology
Amyloid-beta related angiitis (ABRA) of the central nervous system (CNS) is a rare disorder with overlapping features of primary angiits of the CNS (PACNS) and cerebral amyloid angiopathy (CAA). We evaluated a 74-year-old man with intermittent left s
Autor:
Richard S. Hotchkiss, Angelica K. Gierut, Harris Perlman, G. Kenneth Haines, Alexander V. Misharin, Shawn Rose
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 10, Iss 1, p 190 (2012)
Journal of Translational Medicine, Vol 10, Iss 1, p 190 (2012)
Background Substantial advances have been generated in understanding the pathogenesis of rheumatoid arthritis (RA). Current murine models of RA-like disease have provided great insights into the molecular mechanism of inflammatory arthritis due to th
Autor:
Angelica K. Gierut, Dimitrios Balomenos, Hemant Agrawal, Harris Perlman, G. Kenneth Haines, Deborah V. Novack, Evan W. Weber, Alexander V. Misharin, Carla M. Cuda, Melissa Mavers
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
OBJECTIVE: The mechanism responsible for persistent synovial inflammation in rheumatoid arthritis (RA) is unknown. Previously, we demonstrated that expression of the cyclin-dependent kinase inhibitor p21 is reduced in synovial tissue from RA patients
Autor:
Alexander V. Misharin, Andrew R. Clark, Christopher D. Buckley, G. K. Kenneth Haines, Rana Saber, Angelica K. Gierut, G. R. Scott Budinger, Sergejs Berdnikovs, Jason D. Turner, Harris Perlman, Carla M. Cuda, Gökhan M. Mutlu, Andrew Filer
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 591-604 (2014)
Different subsets and/or polarized phenotypes of monocytes and macrophages may play distinct roles during the development and resolution of inflammation. Here, we demonstrate in a murine model of rheumatoid arthritis that nonclassical Ly6C(-) monocyt