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Evaluation of thermal stability and kinetic of degradation for levodopa in non-isothermal conditions
Autor:
Titus Vlase, Angelica Caunii, Marius Murariu, Gabriela Vlase, Ionut Ledeti, Bianca Baul, Tudor Olariu, Adriana Ledeti, Denisa Circioban
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 131:1881-1888
In this paper, we present the results obtained during the investigation of thermal stability of antiparkinsonian drug Levodopa in oxidative atmosphere and under non-isothermal conditions. As investigational tools, thermoanalytical methods were used a
Autor:
Lenuta-Maria Suta, Angelica Caunii, Titus Vlase, Marius Murariu, S Bolintineanu, Gabriela Vlase, Ionut Ledeti, Adriana Ledeti, Denisa Circioban
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 130:433-441
Levodopa (L-Dopa or LD) is nowadays considered one of the essential medicines in the World Health Organization list, being a main treatment component for Parkinson’s disease. This paper deals with the investigation of solid-state stability and comp
Autor:
Lenuţa-Maria Şuta, Ionuţ Ledeţi, Marius Murariu, Titus Vlase, Angelica Caunii, Adriana Ledeţi, Cristina Dehelean, Mihaela Budiul, Denisa Circioban, Gabriela Vlase, S Bolintineanu, Petru Matusz
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 131:191-199
Nortriptyline (NRT), usually conditioned as hydrochloride, is a second-generation tricyclic antidepressant that is primarily used as a treatment option for major depression and chronic pain. In this study, a compatibility evaluation between an active
Autor:
Gabriela Vlase, Angelica Caunii, Marius Murariu, Cristina Dehelean, Titus Vlase, Adriana Ledeti, Lenuta-Maria Suta, S Bolintineanu, Ionut Ledeti, Denisa Circioban
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 130:425-431
Donepezil (Don) is one of the main compounds used in the therapy of Alzheimer’s disease. In this study, donepezil hydrochloride was investigated for solid-state compatibility with several pharmaceutical excipients like calcium lactate (CaL), mannit