Refractory Gilles de la Tourette Syndrome—Many Pieces That Define the Puzzle

Autor: Natalia Szejko, Adam Lombroso, Michael H. Bloch, Angeli Landeros-Weisenberger, James F. Leckman

Publikováno v: Frontiers in Neurology, Vol 11 (2020)

Gilles de la Tourette syndrome (GTS) is a childhood onset neuropsychiatric disorder characterized by the presence of motor and vocal tics. The clinical spectrum of GTS is heterogeneous and varies from mild cases that do not require any medical attent

Externí odkaz: https://doaj.org/article/94216ad90d4249fa81d25c6aca44b0a3

Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial

Autor: Jessica A. Johnson, Michael H. Bloch, Angeli Landeros-Weisenberger, José M. Flores, Jennifer B. Dwyer, Gerard Sanacora, Kevin Couloures, Amalia Londono Tobon, Madeeha Nasir

Publikováno v: Focus (Am Psychiatr Publ)

OBJECTIVE: Adolescent depression is prevalent and is associated with significant morbidity and mortality. Although intravenous ketamine has shown efficacy in adult treatment-resistant depression, its efficacy in pediatric populations is unknown. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c859cfe45d3dbbd16fd0b58dcdee8ab8
https://doi.org/10.1176/appi.focus.22020004

Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids

Autor: Melanie V. Brady, Jessica Mariani, Yildiz Koca, Anna Szekely, Robert A. King, Michael H. Bloch, Angeli Landeros-Weisenberger, James F. Leckman, Flora M. Vaccarino

Publikováno v: Mol Psychiatry

Tourette Syndrome (TS) is a neuropsychiatric disorder thought to involve a reduction of basal ganglia (BG) interneurons and malfunctioning of the BG circuitry. However, whether interneurons fail to develop or are lost postnatally remains unknown. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c5226ebb39fbbd7a3c752f453dbe4b
https://pubmed.ncbi.nlm.nih.gov/36447010

Systematic Review and Meta-analysis:An Empirical Approach to Defining Treatment Response and Remission in Pediatric Obsessive-Compulsive Disorder

Autor: Jessica A. Johnson, Fernando R. Asbahr, Michael H. Bloch, Wayne K. Goodman, Michelle Rozenman, Brent J. Small, Eva Serlachius, Divya Ramakrishnan, Cynthia Turner, Adam B. Lewin, Eric A. Storch, Luis C. Farhat, Edoardo F.Q. Vattimo, David Mataix-Cols, Jennifer B. Freeman, John Piacentini, Mohammad Shabani, Gudmundur Skarphedinsson, Angeli Landeros-Weisenberger, Fenghua Li, Daniel Fatori, Fabian Lenhard, Jessica L.S. Levine, Tara S. Peris, Paul Grant, Lisa J. Merlo, Tord Ivarsson, Roseli G. Shavitt, Martin E. Franklin, Daniel A. Geller, Per Hove Thomsen, Bekir B. Artukoglu, Isobel Heyman, Ana I. Rosa-Alcázar, Sandra L. Cepeda, Jonathan S. Comer, Ángel Rosa-Alcázar, Bernhard Weidle, Euripedes Constantino Miguel, Susan E. Swedo, Hamid Mohsenabadi, Jeffrey Sapyta

Publikováno v: Farhat, L C, Vattimo, E F Q, Ramakrishnan, D, Levine, J L S, Johnson, J A, Artukoglu, B B, Landeros-Weisenberger, A, Asbahr, F R, Cepeda, S L, Comer, J S, Fatori, D, Franklin, M E, Freeman, J B, Geller, D A, Grant, P J, Goodman, W K, Heyman, I, Ivarsson, T, Lenhard, F, Lewin, A B, Li, F, Merlo, L J, Mohsenabadi, H, Peris, T S, Piacentini, J, Rosa-Alcázar, A I, Rosa-Alcázar, À, Rozenman, M, Sapyta, J J, Serlachius, E, Shabani, M J, Shavitt, R G, Small, B J, Skarphedinsson, G, Swedo, S E, Thomsen, P H, Turner, C, Weidle, B, Miguel, E C, Storch, E A, Mataix-Cols, D & Bloch, M H 2022, ' Systematic Review and Meta-analysis : An Empirical Approach to Defining Treatment Response and Remission in Pediatric Obsessive-Compulsive Disorder ', Journal of the American Academy of Child and Adolescent Psychiatry, vol. 61, no. 4, pp. 495–507 . https://doi.org/10.1016/j.jaac.2021.05.027

Objective A lack of universal definitions for response and remission in pediatric obsessive-compulsive disorder (OCD) has hampered the comparability of results across trials. To address this problem, we conducted an individual participant data diagno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e37bebdd9f218b7b5218d8f10c6d36c
https://pure.au.dk/portal/da/publications/systematic-review-and-metaanalysis(7d43ec9c-1a39-42b7-ab31-5a26ed74689d).html

Racial Implicit Associations in Psychiatric Diagnosis, Treatment, and Compliance Expectations

Autor: Victor J Avila-Quintero, Jerome H. Taylor, Okoduwa Aboiralor, Michael H. Bloch, Amalia Londono Tobon, José M. Flores, Isaac Johnson, Angeli Landeros-Weisenberger

Publikováno v: Acad Psychiatry

OBJECTIVE: Racial and ethnic disparities are well documented in psychiatry, yet suboptimal understanding of underlying mechanisms of these disparities undermines diversity, inclusion, and education efforts. Prior research suggests that implicit assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb71e3cb855e0768f0e07f19b8d5462
https://pubmed.ncbi.nlm.nih.gov/33821450