Výsledky vyhledávání - "Angeles Mison"

Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome

Autor: Hong Pei, Pushpa-Rekha Thimmalapura, Jerry L. Nadler, Angeles Mison, Jiali Gu

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 290:E92-E102

Insulin resistance (IR) is associated with an increased risk of cardiovascular diseases. The obese Zucker rat (ZR) is a model of IR that shows markedly increased insulin and triglyceride concentrations without major changes in glucose. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94720fa9d86d2b6312b909e71c697356
https://doi.org/10.1152/ajpendo.00133.2005

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12-lipoxygenase pathway increases aldosterone production, 3',5'-cyclic adenosine monophosphate response element-binding protein phosphorylation, and p38 mitogen-activated protein kinase activation in H295R human adrenocortical cells

Autor: Yeshao Wen, Jerry L. Nadler, Angeles Mison, Jiali Gu

Publikováno v: Endocrinology. 144(2)

Evidence suggests that the 12-lipoxygenase (LO) pathway mediates angiotensin II (Ang II)-induced aldosterone synthesis in adrenal glomerulosa cells. To study the mechanisms of 12-LO pathway on aldosterone synthesis, the human adrenocortical cell line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368e970f8c1c68b329b8cfc741929dd1
https://pubmed.ncbi.nlm.nih.gov/12538614

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