Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Angeles Mecate-Zambrano"'
Autor:
Sebastian Schloer, Linda Brunotte, Jonas Goretzko, Angeles Mecate-Zambrano, Nadia Korthals, Volker Gerke, Stephan Ludwig, Ursula Rescher
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2245-2255 (2020)
ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic caused by the Severe Acute Respiratory Syndrome Related Coronavirus 2 (SARS-CoV-2) is a global health emergency. As only very limited therapeutic options are clinically available, there is an u
Externí odkaz:
https://doaj.org/article/bcf82b4bf73a42dcb504646c60eb279b
Autor:
Angeles Mecate-Zambrano, Swathi Sukumar, Guiscard Seebohm, Kevin Ciminski, André Schreiber, Darisuren Anhlan, Lilo Greune, Ludmilla Wixler, Stephanie Grothe, Nora Caroline Stein, M Alexander Schmidt, Klaus Langer, Martin Schwemmle, Tianlai Shi, Stephan Ludwig, Yvonne Boergeling
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008775 (2020)
Small RNA viruses only have a very limited coding capacity, thus most viral proteins have evolved to fulfill multiple functions. The highly conserved matrix protein 1 (M1) of influenza A viruses is a prime example for such a multifunctional protein,
Externí odkaz:
https://doaj.org/article/fefccbf695be46aa806a99952163c902
Autor:
Linda Brunotte, Shuyu Zheng, Angeles Mecate-Zambrano, Jing Tang, Stephan Ludwig, Ursula Rescher, Sebastian Schloer
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1400 (2021)
The ongoing SARS-CoV-2 pandemic requires efficient and safe antiviral treatment strategies. Drug repurposing represents a fast and low-cost approach to the development of new medical treatment options. The direct antiviral agent remdesivir has been r
Externí odkaz:
https://doaj.org/article/f0fff4fd462e4475bfbb1431db4ed90d
Shooting at a Moving Target—Effectiveness and Emerging Challenges for SARS-CoV-2 Vaccine Development
Autor:
Franziska Günl, Angeles Mecate-Zambrano, Selina Rehländer, Saskia Hinse, Stephan Ludwig, Linda Brunotte
Publikováno v:
Vaccines, Vol 9, Iss 10, p 1052 (2021)
Since late 2019 the newly emerged pandemic SARS-CoV-2, the causative agent of COVID-19, has hit the world with recurring waves of infections necessitating the global implementation of non-pharmaceutical interventions, including strict social distanci
Externí odkaz:
https://doaj.org/article/2b60f6ca1470434ea598fb9f5503aace
Autor:
Katja Hönzke, Benedikt Obermayer, Christin Mache, Diana Fatykhova, Mirjana Kessler, Simon Dökel, Emanuel Wyler, Morris Baumgardt, Anna Löwa, Karen Hoffmann, Patrick Graff, Jessica Schulze, Maren Mieth, Katharina Hellwig, Zeynep Demir, Barbara Biere, Linda Brunotte, Angeles Mecate-Zambrano, Judith Bushe, Melanie Dohmen, Christian Hinze, Sefer Elezkurtaj, Mario Tönnies, Torsten T. Bauer, Stephan Eggeling, Hong-Linh Tran, Paul Schneider, Jens Neudecker, Jens C. Rückert, Kai M. Schmidt-Ott, Jonas Busch, Frederick Klauschen, David Horst, Helena Radbruch, Josefine Radke, Frank Heppner, Victor M. Corman, Daniela Niemeyer, Marcel A. Müller, Christine Goffinet, Ronja Mothes, Anna Pascual-Reguant, Anja Erika Hauser, Dieter Beule, Markus Landthaler, Stephan Ludwig, Norbert Suttorp, Martin Witzenrath, Achim D. Gruber, Christian Drosten, Leif-Erik Sander, Thorsten Wolff, Stefan Hippenstiel, Andreas C. Hocke
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilises the angiotensin-converting enzyme 2 (ACE2) transmembrane peptidase as cellular entry receptor. However, whether SARS-CoV-2 in the alveolar compartment is strictly ACE2-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acfc0972291e89181040408e1f0a61b
http://edoc.mdc-berlin.de/21721/2/21721suppl.pdf
http://edoc.mdc-berlin.de/21721/2/21721suppl.pdf
Autor:
Aileen Faist, Sebastian Schloer, Angeles Mecate-Zambrano, Josua Janowski, André Schreiber, Yvonne Boergeling, Beate C.G. Conrad, Sriram Kumar, Leonie Toebben, Klaus Schughart, Morris Baumgardt, Mirjana Kessler, Katja Hoenzke, Andreas Hocke, Marcel Trautmann, Wolfgang Hartmann, Hiroki Kato, Ursula Rescher, Anmari Christersson, Joachim Kuehn, Alexander Mellmann, Thorsten Wolff, Philip Kuempers, Alexandros Rovas, Rainer Wiewrodt, Karsten Wiebe, Peter Barth, Stephan Ludwig, Linda Brunotte
Publikováno v:
Antiviral research. 209
SARS-CoV-2 is the causative agent of the immune response-driven disease COVID-19 for which new antiviral and anti-inflammatory treatments are urgently needed to reduce recovery time, risk of death and long COVID development. Here, we demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8764ca52f12ee7224a33610cd8e53368
https://pubmed.ncbi.nlm.nih.gov/36423831
https://pubmed.ncbi.nlm.nih.gov/36423831
Autor:
Linda Brunotte, Stephan Ludwig, Angeles Mecate-Zambrano, Ursula Rescher, Shuyu Zheng, Jing Tang, Sebastian Schloer
Publikováno v:
British Journal of Pharmacology
Background and Purpose The SARS-COV-2 pandemic and the global spread of coronavirus disease 2019 (COVID-19) urgently call for efficient and safe antiviral treatment strategies. A straightforward approach to speed up drug development at lower costs is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaa9753790d7dd6090824ba5adae23f
https://doi.org/10.1111/bph.15418
https://doi.org/10.1111/bph.15418
Autor:
André Schreiber, Dorothee Viemann, Jennifer Schöning, Sebastian Schloer, Angeles Mecate Zambrano, Linda Brunotte, Aileen Faist, Michael Schöfbänker, Eike Hrincius, Helen Hoffmann, Markus Hoffmann, Stefan Pöhlmann, Ursula Rescher, Oliver Planz, Stephan Ludwig
Publikováno v:
Cellular and Molecular Life Sciences
Coronavirus disease 2019 (COVID-19), the illness caused by a novel coronavirus now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to more than 260 million confirmed infections and 5 million deaths to date. While vaccinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a744f9d55489a2e8a3917a5e0093a4
https://doi.org/10.1007/s00018-021-04085-1
https://doi.org/10.1007/s00018-021-04085-1
Autor:
Hans Robert Schoeler, Stephan Ludwig, Angeles Mecate-Zambrano, Linda Brunotte, Aaron Lecanda, Yotam Menuchin-Lasowski, André Schreiber, Thomas Rauen, Olympia E. Psathaki
Several studies have pointed to retinal involvement in COVID-19 disease, yet many questions remain regarding the ability of SARS-CoV-2 to infect and replicate in retinal cells and its effects on the retina. Here we have used human stem cell–derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46de38b299800e810c45ff8068804192
https://doi.org/10.1101/2021.10.09.463766
https://doi.org/10.1101/2021.10.09.463766
Autor:
Yotam Menuchin-Lasowski, André Schreiber, Aarón Lecanda, Angeles Mecate-Zambrano, Linda Brunotte, Olympia E. Psathaki, Stephan Ludwig, Thomas Rauen, Hans R. Schöler
Publikováno v:
Stem cell reports. 17(4)
Several studies have pointed to retinal involvement in COVID-19, yet many questions remain regarding the ability of SARS-CoV-2 to infect and replicate in retinal cells and its effects on the retina. Here, we have used human pluripotent stem cell-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7568b752448abbea76605992ddf2c5a1
https://pubmed.ncbi.nlm.nih.gov/35334213
https://pubmed.ncbi.nlm.nih.gov/35334213