Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Angeles Estelles"'
Autor:
Arun K Kashyap, John Steel, Adam Rubrum, Angeles Estelles, Raffaella Briante, Natalia A Ilyushina, Li Xu, Ryann E Swale, Aleksandr M Faynboym, Pamela K Foreman, Michael Horowitz, Lawrence Horowitz, Richard Webby, Peter Palese, Richard A Lerner, Ramesh R Bhatt
Publikováno v:
PLoS Pathogens, Vol 6, Iss 7, p e1000990 (2010)
Influenza viruses elude immune responses and antiviral chemotherapeutics through genetic drift and reassortment. As a result, the development of new strategies that attack a highly conserved viral function to prevent and/or treat influenza infection
Externí odkaz:
https://doaj.org/article/6215bc65a50e44a2b76bc04a259a4c3f
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0219256 (2019)
PLoS ONE, Vol 14, Iss 7, p e0219256 (2019)
We have previously described a native human monoclonal antibody, TRL1068, that disrupts bacterial biofilms by extracting from the biofilm matrix key scaffolding proteins in the DNABII family, which are present in both gram positive and gram negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f873a8f88cb09f64a0538ea25466da
https://pubmed.ncbi.nlm.nih.gov/31287831
https://pubmed.ncbi.nlm.nih.gov/31287831
Autor:
Christian L. Barrett, Angeles Estelles, Taguchi Alex T, Hauser Kevin Eduard, Morin Andrew, Isaac Bright, Matt Greving, Bing Li, Mohan Srinivasan, Gip Phung Tu, Willis Jordan R, Oleg Gurinovich, Piotr Zalicki, Hanako Daino-Laizure
Publikováno v:
Cancer Research. 80:6055-6055
Therapeutic antibodies have contributed significantly to better clinical outcomes across multiple tumor types. However, there is still unmet clinical need in cancers with an immunosuppressive and stroma rich tumor microenvironment (TME). One key limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad700aa19bc91f84e6e19293dd86a196
https://doi.org/10.1158/1538-7445.am2020-6055
https://doi.org/10.1158/1538-7445.am2020-6055
Autor:
Adam Vigil, Michael Wittekind, Scott Johnson, Lawrence M. Kauvar, Angeles Estelles, Ralph A. Tripp
Publikováno v:
Antimicrobial Agents and Chemotherapy
Although antibodies that effectively neutralize a broad set of influenza viruses exist in the human antibody repertoire, they are rare. We used a single-cell screening technology to identify rare monoclonal antibodies (MAbs) that recognized a broad s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b47c42dc2c9d39e2d85983284efd1d
https://pubmed.ncbi.nlm.nih.gov/29507069
https://pubmed.ncbi.nlm.nih.gov/29507069
Autor:
Edgar Tenorio, Liang Li, Lawrence M. Kauvar, Stefan Ryser, Anton Leighton, Arnold S. Bayer, Wessam Abdelhady, Yan Q. Xiong, Angeles Estelles, R. Gonzales
Publikováno v:
Antimicrobial agents and chemotherapy. 61(10)
Many serious bacterial infections are antibiotic refractory due to biofilm formation. A key structural component of biofilm is extracellular DNA, which is stabilized by bacterial proteins, including those from the DNABII family. TRL1068 is a high-aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be48d7d6d0eb9f6ab8c12dcabad2a45
https://pubmed.ncbi.nlm.nih.gov/28717038
https://pubmed.ncbi.nlm.nih.gov/28717038
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0181464 (2017)
PLoS ONE, Vol 12, Iss 7, p e0181464 (2017)
We report here the cloning of native high affinity anti-TIM-3 and anti-KIR IgG monoclonal antibodies (mAbs) from peripheral blood mononuclear cells (PBMC) of healthy human donors. The cells that express these mAbs are rare, present at a frequency of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c08ab662bc4dc423e4a99c27c06ea2e
https://pubmed.ncbi.nlm.nih.gov/28723950
https://pubmed.ncbi.nlm.nih.gov/28723950
Autor:
Da Nguyen, Edgar Tenorio, Yifan Yang, Keyi Liu, Jianzhong Zhang, Manfred Heidecker, Robert Stephenson, Anne-Kathrin Woischnig, Stefan Ryser, Anton Leighton, Nina Khanna Gremmelmaier, Reyna J. Simon, Lawrence M. Kauvar, Evelene Lomongsod, Angeles Estelles, Stote Ellsworth
Many serious bacterial infections are difficult to treat due to biofilm formation, which provides physical protection and induces a sessile phenotype refractory to antibiotic treatment compared to the planktonic state. A key structural component of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d27b4d3c68e945f2c96cdd6e2a209c1
https://europepmc.org/articles/PMC4808150/
https://europepmc.org/articles/PMC4808150/
Autor:
Alain Delcayre, Janeth Villanueva, SuSu Khine, Barbara Aguilar, Angeles Estelles, Pedro Paz, Jeffrey Joseph Sperinde, Thibaut Roulon, Jean-Bernard Le Pecq
Publikováno v:
Blood Cells, Molecules, and Diseases. 35:158-168
Exosome Display is a novel methodology enabling the manipulation of exosome protein content. This technology stems from the identification of addressing domains that mediate the specific distribution of proteins on exosomes. More particularly, Lactad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e95ff45dc4dabc0e5ac0895cd6f42f4
https://doi.org/10.1016/j.bcmd.2005.07.003
https://doi.org/10.1016/j.bcmd.2005.07.003
Autor:
Da Ngyen, Angeles Estelles, Yifan Yang, Manfred Heideker, Evelene Lomongsod, Lawrence M. Kauvar, Robert A. Stephenson, Mikhail L. Gishizky, Stefan Ryser, Jianzhong Zhzng, Keyi Liu
Publikováno v:
Cancer Research. 76:594-594
The immunosurveillance/immunoediting theory postulates that tumor growth is repressed in healthy individuals through the activation of adaptive and innate immune mechanisms. The clinical success of antibodies that target inhibitory checkpoint pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8af90f9941bbde13904438fd09230edc
https://doi.org/10.1158/1538-7445.am2016-594
https://doi.org/10.1158/1538-7445.am2016-594
Autor:
Aleksandr M. Faynboym, John Steel, Ramesh R. Bhatt, Li Xu, Richard A. Lerner, Peter Palese, Ryann E. Swale, Angeles Estelles, Raffaella Briante, Pamela K. Foreman, Adam Rubrum, Richard J. Webby, Lawrence Horowitz, Natalia A. Ilyushina, Arun K. Kashyap, Michael Horowitz
Publikováno v:
PLoS Pathogens, Vol 6, Iss 7, p e1000990 (2010)
PLoS Pathogens
PLoS Pathogens
Influenza viruses elude immune responses and antiviral chemotherapeutics through genetic drift and reassortment. As a result, the development of new strategies that attack a highly conserved viral function to prevent and/or treat influenza infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379abfc0c1c26290278142d9001836af
http://europepmc.org/articles/PMC2900296?pdf=render
http://europepmc.org/articles/PMC2900296?pdf=render