Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Angele De Silva"'
Autor:
Sammy Alhassen, Siwei Chen, Lamees Alhassen, Alvin Phan, Mohammad Khoudari, Angele De Silva, Huda Barhoosh, Zitong Wang, Chelsea Parrocha, Emily Shapiro, Charity Henrich, Zicheng Wang, Leon Mutesa, Pierre Baldi, Geoffrey W. Abbott, Amal Alachkar
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Sammy Alhassen, Siwei Chen, et al. use mouse models to examine the effects of prenatal and postnatal stress on metabolomic and transcriptomic pathways in the brain. Their results suggest that altered mitochondrial metabolism may underlie trauma-induc
Externí odkaz:
https://doaj.org/article/8349a6b2dd754f9e98b7e196962d95a5
Autor:
Leon Mutesa, Pierre Baldi, Charity Henrich, Lamees Alhassen, Alvin Phan, Emily Shapiro, Huda Barhoosh, Geoffrey W. Abbott, Chelsea Marie T. Parrocha, Zicheng Wang, Mohammad Khoudari, Angele De Silva, Zitong Wang, Siwei Chen, Amal Alachkar, Sammy Alhassen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications biology, vol 4, iss 1
Communications Biology
Communications biology, vol 4, iss 1
Intergenerational trauma increases lifetime susceptibility to depression and other psychiatric disorders. Whether intergenerational trauma transmission is a consequence of in-utero neurodevelopmental disruptions versus early-life mother–infant inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ffd19df4c889b360580376730ef26f
https://doaj.org/article/8349a6b2dd754f9e98b7e196962d95a5
https://doaj.org/article/8349a6b2dd754f9e98b7e196962d95a5
Autor:
Geoffrey W. Abbott, Torsten K. Roepke, Rían W. Manville, Clemens Köhncke, Angele De Silva, Bettina Purfürst, Ulrike Lisewski, Leonhard Schleussner, Soo Min Lee
Publikováno v:
FASEB J
Heart failure (HF) is an increasing global health crisis, affecting 40 million people and causing 50% mortality within 5 years of diagnosis. A fuller understanding of the genetic and environmental factors underlying HF, and novel therapeutic approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a79a73cad6a27f6857e8f20c216ab8
https://doi.org/10.1096/fj.202000013rr
https://doi.org/10.1096/fj.202000013rr
Autor:
Charity Henrich, Emily Shapiro, Siwei Chen, Pierre Baldi, Geoffrey W. Abbott, Alvin Phan, Zicheng Wang, Amal Alachkar, Leon Mutesa, Angele De Silva, Sammy Alhassen, Lamees Alhassen, Zitong Wang, Mohammad Khoudari, Huda Barhoosh, Chelsea Marie T. Parrocha
Intergenerational stress increases lifetime susceptibility to depression and other psychiatric disorders. Whether intergenerational stress transmission is a consequence of in utero neurodevelopmental disruptions vs early-life mother-infant interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f952e2cdf39b6d707f70ff9205b4260a
https://doi.org/10.1101/2021.04.09.438868
https://doi.org/10.1101/2021.04.09.438868
Autor:
Pierre Baldi, Ryan F. Yoshimura, Wedad Alhassen, Siwei Chen, Amal Alachkar, Geoffrey W. Abbott, Angele De Silva
Publikováno v:
Communications biology, vol 3, iss 1
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
The imbalance of prenatal micronutrients may perturb one-carbon (C1) metabolism and increase the risk for neuropsychiatric disorders. Prenatal excessive methionine (MET) produces in mice behavioral phenotypes reminiscent of human schizophrenia. Wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa925c167c02feb5fb1c76b9c3973fc
https://escholarship.org/uc/item/7141x617
https://escholarship.org/uc/item/7141x617
Publikováno v:
De Silva, Angele M; Manville, Rian W; & Abbott, Geoffrey W. (2018). Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation. SCIENCE ADVANCES, 4(11), eaav0824. doi: 10.1126/sciadv.aav0824. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8zq9p91p
Science Advances
Science Advances
Analysis of a leaf extract used in African folk medicine reveals a high-affinity K+ channel agonist and its binding site.
A third of the global population relies heavily upon traditional or folk medicines, such as the African shrub Mallotus oppo
A third of the global population relies heavily upon traditional or folk medicines, such as the African shrub Mallotus oppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8ed9c488a091e4b845bb647d95cf33
https://doi.org/10.1126/sciadv.aav0824
https://doi.org/10.1126/sciadv.aav0824