Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Angela Wadsworth"'
Autor:
Brian Wong, Dirk G Brockstedt, Lisa A Marshall, Sachie Marubayashi, Aparna Jorapur, Scott Jacobson, Mikhail Zibinsky, Omar Robles, Dennis Xiaozhou Hu, Jeffrey J Jackson, Deepa Pookot, Jerick Sanchez, Martin Brovarney, Angela Wadsworth, David Chian, David Wustrow, Paul D Kassner, Gene Cutler, Oezcan Talay
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Checkpoint inhibitors (CPIs) such as anti-PD(L)-1 and anti-CTLA-4 antibodies have resulted in unprecedented rates of antitumor responses and extension of survival of patients with a variety of cancers. But some patients fail to respond or
Externí odkaz:
https://doaj.org/article/3beb97b17518498284642adadb08fbeb
Autor:
Scott Jacobson, Dennis X. Hu, Cesar Meleza, Mikhail Zibinsky, Ashkaan Younai, Erin Riegler, Omar Robles, Jenny McKinnell, Emily Karbarz, Paul D. Kassner, Lisa A. Marshall, Maureen Kay Reilly, David Chian, Gene Cutler, David J. Wustrow, Dirk G. Brockstedt, Hunter P. Shunatona, Raymond Diokno, Angela Wadsworth, John M. Ketcham, Oezcan Talay, Jeffrey J. Jackson
Publikováno v:
Journal of Medicinal Chemistry. 63:8584-8607
The C-C chemokine receptor 4 (CCR4) is broadly expressed on regulatory T cells (Treg) as well as other circulating and tissue-resident T cells. Treg can be recruited to the tumor microenvironment (TME) through the C-C chemokines CCL17 and CCL22. Treg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff8f25af0448a07583421b7d8d0bfa7
https://doi.org/10.1021/acs.jmedchem.0c00988
https://doi.org/10.1021/acs.jmedchem.0c00988
Autor:
Diana Egerton‐Warburton, Andrew Gosbell, Angela Wadsworth, Drew Richardson, Daniel M. Fatovich
Publikováno v:
Australian and New Zealand Journal of Public Health, Vol 42, Iss 2, Pp 218-218 (2018)
Externí odkaz:
https://doaj.org/article/ea15c1a4a4e34e3184e1d5f6bba1aea2
Autor:
Deepa Pookot, Scott Jacobson, John M. Ketcham, David Chian, Emily Karbarz, Dennis X. Hu, James Ross Walker, Gene Cutler, Ashkaan Younai, Mikhail Zibinsky, Raymond Diokno, David J. Wustrow, Betty Abraham, Angela Wadsworth, Maureen Kay Reilly, Cesar Meleza, Jenny McKinnell, Jeffrey J. Jackson, Abood Okal, Paul D. Kassner, Lisa A. Marshall, Oezcan Talay, Berenger Biannic, Bui Minna H T, Hilary Plake Beck, Hunter P. Shunatona, Omar Robles
Publikováno v:
Journal of Medicinal Chemistry. 62:6190-6213
Recruitment of suppressive CD4+ FOXP3+ regulatory T cells (Treg) to the tumor microenvironment (TME) has the potential to weaken the antitumor response in patients receiving treatment with immuno-oncology (IO) agents. Human Treg express CCR4 and can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c664d1b35dae60b88d59898f44ef53
https://doi.org/10.1021/acs.jmedchem.9b00506
https://doi.org/10.1021/acs.jmedchem.9b00506
Autor:
Lisa A, Marshall, Sachie, Marubayashi, Aparna, Jorapur, Scott, Jacobson, Mikhail, Zibinsky, Omar, Robles, Dennis Xiaozhou, Hu, Jeffrey J, Jackson, Deepa, Pookot, Jerick, Sanchez, Martin, Brovarney, Angela, Wadsworth, David, Chian, David, Wustrow, Paul D, Kassner, Gene, Cutler, Brian, Wong, Dirk G, Brockstedt, Oezcan, Talay
Publikováno v:
Journal for Immunotherapy of Cancer
Background Checkpoint inhibitors (CPIs) such as anti-PD(L)-1 and anti-CTLA-4 antibodies have resulted in unprecedented rates of antitumor responses and extension of survival of patients with a variety of cancers. But some patients fail to respond or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71b1b78ef78bf14b688ae88aeb0b78a2
https://pubmed.ncbi.nlm.nih.gov/33243932
https://pubmed.ncbi.nlm.nih.gov/33243932
Autor:
Omar Robles, Sachie Marubayashi, Brian Wong, Angela Wadsworth, Paul D. Kassner, Lisa A. Marshall, Gene Cutler, David J. Wustrow, Jerick Sanchez, David Chian, Martin Brovarney, Jeffrey J. Jackson, Dirk G. Brockstedt, Oezcan Talay, Scott Jacobson, Mikhail Zibinsky, Aparna Jorapur, Deepa Pookot, Hu Dennis X
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
BackgroundCheckpoint inhibitors (CPIs) such as anti-PD(L)-1 and anti-CTLA-4 antibodies have resulted in unprecedented rates of antitumor responses and extension of survival of patients with a variety of cancers. But some patients fail to respond or i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c01a0f38bd23a23e5bf3b0d7c4a865
https://jitc.bmj.com/content/8/2/e000764.full
https://jitc.bmj.com/content/8/2/e000764.full
Publikováno v:
Sociation Today, Vol 10, Iss 1 (2012)
United States manufacturing has undergone intensive economic restructuring over the last thirty years. This has had a profound effect on rural areas, especially in the Southeast where textile, apparel, and furniture manufacturing have been based. Nor
Externí odkaz:
https://doaj.org/article/e0402f8b458444d3bf7e38134a136cfa
Autor:
Diana Egerton-Warburton, Andrew Gosbell, Daniel M Fatovich, Drew B Richardson, Katie Moore, Angela Wadsworth
Publikováno v:
Addiction. 113:623-632
Background and aims: Emergency department (ED) alcohol‐related presentation data are not routinely collected in Australia and New Zealand. It is likely that previous research has underestimated the numbers of patients presenting with alcohol‐rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b0c7cdd06681f5f0008953b51400f07
https://doi.org/10.1111/add.14109
https://doi.org/10.1111/add.14109
Autor:
Jeffrey J, Jackson, John M, Ketcham, Ashkaan, Younai, Betty, Abraham, Berenger, Biannic, Hilary P, Beck, Minna H T, Bui, David, Chian, Gene, Cutler, Raymond, Diokno, Dennis X, Hu, Scott, Jacobson, Emily, Karbarz, Paul D, Kassner, Lisa, Marshall, Jenny, McKinnell, Cesar, Meleza, Abood, Okal, Deepa, Pookot, Maureen K, Reilly, Omar, Robles, Hunter P, Shunatona, Oezcan, Talay, James R, Walker, Angela, Wadsworth, David J, Wustrow, Mikhail, Zibinsky
Publikováno v:
Journal of medicinal chemistry. 62(13)
Recruitment of suppressive CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85180faa74d36bfcafdd7b76884ccac3
https://pubmed.ncbi.nlm.nih.gov/31259550
https://pubmed.ncbi.nlm.nih.gov/31259550
Autor:
Buvana Ravishankar, Lavanya Adusumilli, Deepa Pookot Pookot, Emily Huang, Raashi Sreenivasan, Lisa Marshall, Deepika Kaveri, Oezcan Talay, Silpa Suthram, Svetlana Miakicheva, Abood Okal, Mikhail Zibinsky, Jeffrey Jackson, Grant Shibuya, Paul Leger, Parcharee Tivitmahaisoon, Scott Jacobson, Steve Wong, Angela Wadsworth, Jerick Sanchez, Martin Brovarney, David Chian, Sachie Marubayashi, Aparna Jorapur, Delia Bradford, Christophe Colas, Gene Cutler, Jacob Schwartz, David Wustrow, Paul Kassner, Dirk Brockstedt
Publikováno v:
Cancer Research. 79:1104-1104
The tumor microenvironment (TME) is characterized by deficiencies in oxygen and key nutrients, such as glucose and amino acids, resulting in an overall immune-suppressive environment. Key suppressive cell types in the TME include tumor, stromal and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d03e198aa5e2aeba4468505e8d78367
https://doi.org/10.1158/1538-7445.am2019-1104
https://doi.org/10.1158/1538-7445.am2019-1104