Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Angela Toms"'
Autor:
Maureen Caligiuri, Grace L. Williams, Jennifer Castro, Linda Battalagine, Erik Wilker, Lili Yao, Shawn Schiller, Angela Toms, Ping Li, Eneida Pardo, Bradford Graves, Joey Azofeifa, Agustin Chicas, Torsten Herbertz, Maria Lai, Joel Basken, Kenneth W. Wood, Qunli Xu, Sylvie M. Guichard
Publikováno v:
Targeted Oncology. 18:269-285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b83a4b5ffa700d6591f630c62f30ad00
https://doi.org/10.1007/s11523-023-00949-7
https://doi.org/10.1007/s11523-023-00949-7
Autor:
Wei-Sheng, Huang, Feng, Li, Yongjin, Gong, Yun, Zhang, Willmen, Youngsaye, Yongjin, Xu, Xiaotian, Zhu, Matthew T, Greenfield, Anna, Kohlmann, Paul M, Taslimi, Angela, Toms, Stephan G, Zech, Tianjun, Zhou, Biplab, Das, Hyun G, Jang, Meera, Tugnait, Yihua E, Ye, Francois, Gonzalvez, Theresa E, Baker, Sara, Nadworny, Yaoyu, Ning, Scott D, Wardwell, Sen, Zhang, Alexandra E, Gould, Yongbo, Hu, Weston, Lane, Robert J, Skene, Hua, Zou, Tim, Clackson, Narayana I, Narasimhan, Victor M, Rivera, David C, Dalgarno, William C, Shakespeare
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 80:129084
In the treatment of non-small cell lung cancer (NSCLC), patients harboring exon 20 insertion mutations in the epidermal growth factor receptor (EGFR) gene (EGFR) have few effective therapies because this subset of mutants is generally resistant to mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36257c29b5ae4b54e2d345df53177fd7
https://doi.org/10.1016/j.bmcl.2022.129084
https://doi.org/10.1016/j.bmcl.2022.129084
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Formin proteins direct the nucleation and assembly of linear actin filaments in a variety of cellular processes using their conserved formin homology 2 (FH2) domain. Diaphanous-related formins (DRFs) are effectors of Rho-family GTPases, and in the ab
Externí odkaz:
https://doaj.org/article/6d7b0364a6a14d35a6e72efd59b416e7
Autor:
Maria Ribadeneira, Lili Yao, Paul Ehrlich, Angela Toms, Sylvie Guichard, Sanjeev Forsyth, Blythe Thomson
Publikováno v:
Neuro Oncol
BACKGROUND Iocitrate dehydrogenase mutations (mIDH1) are present in >70% of patients with Grade II/III gliomas resulting in production and accumulation of (R)-2-hydroxyglutarate (2-HG) causing DNA hypermethylation and promoting tumorigenesis. This ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a628c47b58cca650a0d64393a8f0662
https://europepmc.org/articles/PMC6845728/
https://europepmc.org/articles/PMC6845728/
Autor:
Shuangying Liu, Xiaotian Zhu, Angela Toms, Yongjin Xu, David C. Dalgarno, Rory Dodd, Lois Parillon, Yihan Wang, Scott Wardwell, Tim Clackson, Jiwei Qi, Anna Kohlmann, Yaoyu Ning, Hyun Gyung Jang, Xiaohui Lu, Lisi Cai, Qurish K. Mohemmad, Rongsong Xu, Dong Zou, Sen Zhang, William C. Shakespeare, Timothy A. Dwight, Narayana I. Narasimhan, Qihong Xu, Rana Anjum, Lauren Moran, Tianjun Zhou, Frank Wang, Mathew Thomas, Wei-Sheng Huang, Jeffrey A. Keats, Feng Li, Jan Romero, Victor M. Rivera
Publikováno v:
Journal of medicinal chemistry. 59(10)
In the treatment of echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase positive (ALK+) non-small-cell lung cancer (NSCLC), secondary mutations within the ALK kinase domain have emerged as a major resistance mechanism t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625d183379f1d6b062d2872fda27b944
https://pubmed.ncbi.nlm.nih.gov/27144831
https://pubmed.ncbi.nlm.nih.gov/27144831
Autor:
Caligiuri, Maureen, Williams, Grace L., Castro, Jennifer, Battalagine, Linda, Wilker, Erik, Yao, Lili, Schiller, Shawn, Toms, Angela, Li, Ping, Pardo, Eneida, Graves, Bradford, Azofeifa, Joey, Chicas, Agustin, Herbertz, Torsten, Lai, Maria, Basken, Joel, Wood, Kenneth W., Xu, Qunli, Guichard, Sylvie M.
Publikováno v:
Targeted Oncology; Mar2023, Vol. 18 Issue 2, p269-285, 17p
Autor:
Gordon, Wendy R.1, Vardar-Ulu, Didem1, Histen, Gavin1, Sanchez-Irizarry, Cheryll1, Aster, Jon C.1, Blacklow, Stephen C.1 sblacklow@rics.bwh.harvard.edu
Publikováno v:
Nature Structural & Molecular Biology. Apr2007, Vol. 14 Issue 4, p295-300. 6p. 2 Diagrams, 1 Chart, 1 Graph.
Autor:
Ahles, Tim A.1 ahlest@MSKCC.org, Wasson, John H.2, Seville, Janette L.1, Johnson, Deborah J.2, Cole, Bernard F.2, Hanscom, Brett3, Stukel, Therese A.4,5, McKinstry, Elizabeth1
Publikováno v:
Annals of Family Medicine. Jul/Aug2006, Vol. 4 Issue 4, p341-350. 10p.
Autor:
Husseini, Naji S.1, Alsaied, Osama A.2, Thorne, Robert E.3, Berejnov, Viatcheslav3 vb54@cornell.edu
Publikováno v:
Journal of Applied Crystallography. Apr2006, Vol. 39 Issue 2, p244-251. 8p. 6 Color Photographs, 2 Charts, 10 Graphs.
Autor:
Linda Battalagine, Shawn Schiller, Angela V. Toms, Ping Li, Lili Yao, Maureen Caligiuri, Grace L. Williams, Jennifer Castro, Sylvie Guichard, Kristina R Muskiewicz, Erik Wilker, Eneida Pardo, Kenneth W. Wood, Bradford Graves
Publikováno v:
Cancer Research. 80:3079-3079
Triple negative breast cancer (TNBC) remains a high unmet medical need, commonly treated with chemotherapies. Biomarker-driven treatment strategies have led to the recent approvals of both PARP inhibitors and an immune checkpoint inhibitor for a subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3adb57729a88fc4485b22526b7e9c1
https://doi.org/10.1158/1538-7445.am2020-3079
https://doi.org/10.1158/1538-7445.am2020-3079