Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Angela Thornton"'
Autor:
Thomas M. Nosek, Michael B. Reid, Angela Thornton, Jerome Parness, Noah Weisleder, Brian J. Hardin, Leticia Brotto, Jianjie Ma, Xiaoli Zhao, Sylvain Bougoin, Marco Brotto, Zui Pan
Publikováno v:
Aging (Albany NY)
Muscle atrophy alone is insufficient to explain the significant decline in contractile force of skeletal muscle during normal aging. One contributing factor to decreased contractile force in aging skeletal muscle could be compromised excitation-contr
Autor:
Jianjie Ma, Rachel Campbell, Noah Weisleder, Angela Thornton, Xiaoli Zhao, Marco Brotto, Yaa Oppong
Publikováno v:
Aging Cell. 7:561-568
In aged skeletal muscle, changes to the composition and function of the contractile machinery cannot fully explain the observed decrease in the specific force produced by the contractile machinery that characterizes muscle weakness during aging. Sinc
Autor:
Xiao-Feng Le, Gong Yang, Angela Thornton, Xianfeng Wen, Jinsong Liu, Robert C. Bast, Weiqun Mao
Publikováno v:
Oncogene. 25:6986-6996
We determined the impact of HER2 signaling on two proangiogenic factors, vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8), and on an antiangiogenic factor, thrombospondin-1 (TSP-1). Re-expression of HER2 in MCF-7 and T-47D breast ca
Autor:
Anil K. Sood, Weiqun Mao, Xiao Feng Le, John V. Heymach, Angela Thornton, Chunhua Lu, Robert C. Bast
We have previously reported that breast cancer cells which overexpress HER2 produce higher levels of VEGF than cells with low levels of HER2. This study tested the hypothesis that dual targeting of the VEGF (with VEGF-Trap) and HER2 (with trastuzumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5042cdb2c78006604f6e94bfdf040a
https://europepmc.org/articles/PMC2757147/
https://europepmc.org/articles/PMC2757147/
Publikováno v:
Ethnicitydisease. 18(2 Suppl 2)
Mortality rates for coronary heart disease (CHD) have declined markedly since the early 1970s. However, CHD remains the number one cause of death in the United States. The decline in mortality has been attributed to declines in CHD risk factors (toba
Autor:
Chuanxi Cai, Jae-Kyun Ko, Noah Weisleder, Xiaoli Zhao, Moonsun Hwang, Angela Thornton, Haruko Masumiya, Jianjie Ma, Marco Brotto, Hiroshi Takeshima, Miyuki Nishi, Pei-Hui Lin, Zui Pan, Shinji Komazaki, Noriyuki Matsuda
Publikováno v:
Nature cell biology. 11(1)
Dynamic membrane repair and remodelling is an elemental process that maintains cell integrity and mediates efficient cellular function. Here we report that MG53, a muscle-specific tripartite motif family protein (TRIM72), is a component of the sarcol
Autor:
Angela Thornton, Diane C. Bodurka, Hyun S. Shvartsman, Elvio G. Silva, David M. Gershenson, Michael T. Deavers, Kwong Kwok Wong, Rosemarie Schmandt, Karen H. Lu, Anais Malpica
Publikováno v:
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 26(4)
A 2-tier system that classifies ovarian serous carcinoma (OSC) as low grade or high grade is gaining acceptance. Women with low-grade OSC generally have higher 5-year survival rates than do women with high-grade OSC. We examined the expression of var
Autor:
Noah Weisleder, Jianjie Ma, Yaa Oppong, Rachel Campbell, Marco Brotto, Xiaoli Zhao, Angela Thornton
Publikováno v:
The FASEB Journal. 21
Publikováno v:
The Journal of Immunology. 194:197.20-197.20
Foxp3+ Regulatory T cells (Treg) suppress immune activation and play a critical role in the maintenance of self-tolerance. A subpopulation (70-80%) of Treg cells in both mouse and man express the transcription factor, Helios, but the role of Helios i
Autor:
Russell Broaddus, Stephanie Clifford, Angela Thornton, Charlotte C. Sun, Marsha Bennett, David M. Gershenson, Feng Jiang, Rosemarie Schmandt, Anil K. Sood, Karen H. Lu
Publikováno v:
Cancer biologytherapy. 5(9)
We identified the BRK tyrosine kinase in a PCR-based screen of tyrosine kinases expressed by ovarian tumors. BRK expression is restricted to normal differentiating epithelial cells and its overexpression may play a role in processes related to tumor