Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Angela Stefanachi"'
Autor:
Lucia Sarcina, Pietro Delre, Giovanni Graziano, Angela Stefanachi, Davide Blasi, Rosaria A. Picca, Cinzia Di Franco, Francesco Leonetti, Gaetano Scamarcio, Paolo Bollella, Giuseppe F. Mangiatordi, Eleonora Macchia, Luisa Torsi
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract A plethora of different electronic and optoelectronic devices have been developed lately, for biosensing applications (e.g., label‐free, fast, and easier to operate) based on a detecting interface accommodating the biorecognition elements,
Externí odkaz:
https://doaj.org/article/183ed1f3b8eb41f3a50fbd93705b6040
Publikováno v:
Frontiers in Chemistry, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/f0f6c83024fd49b0a1df7e3dd3ae0306
Autor:
Leonardo Pisani, Marco Catto, Giovanni Muncipinto, Orazio Nicolotti, Antonio Carrieri, Mariagrazia Rullo, Angela Stefanachi, Francesco Leonetti, Cosimo Altomare
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The coumarin core (i.e., 1-benzopyran-2 (2H)-one) is a structural motif highly recurrent in both natural products and bioactive molecules. Indeed, depending on the substituents and branching positions around the byciclic core, coumarin-containing com
Externí odkaz:
https://doaj.org/article/53ff1d25b4064b7f8ec8c3ec6647bf7d
Autor:
Giovanni Graziano, Angela Stefanachi, Marialessandra Contino, Rubén Prieto-Díaz, Alessia Ligresti, Poulami Kumar, Antonio Scilimati, Eddy Sotelo, Francesco Leonetti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6581 (2023)
Multicomponent reactions (MCRs) have emerged as a powerful strategy in synthetic organic chemistry due to their widespread applications in drug discovery and development. MCRs are flexible transformations in which three or more substrates react to fo
Externí odkaz:
https://doaj.org/article/8184e70d550d414c9e7753bfbc3c1df8
Autor:
Davide Blasi, Lucia Sarcina, Angelo Tricase, Angela Stefanachi, Francesco Leonetti, Domenico Alberga, Giuseppe Felice Mangiatordi, Kyriaki Manoli, Gaetano Scamarcio, Rosaria Anna Picca, Luisa Torsi
Publikováno v:
ACS Omega, Vol 5, Iss 27, Pp 16762-16771 (2020)
Externí odkaz:
https://doaj.org/article/79f0aadce21a494b88841e7afa5ce365
Autor:
Rosa Maria Iacobazzi, Annalisa Cutrignelli, Angela Stefanachi, Letizia Porcelli, Angela Assunta Lopedota, Roberta Di Fonte, Antonio Lopalco, Simona Serratì, Valentino Laquintana, Nicola Silvestris, Massimo Franco, Saverio Cellamare, Francesco Leonetti, Amalia Azzariti, Nunzio Denora
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6545 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies, with poor outcomes largely due to its unique microenvironment, which is responsible for the low response to drugs and drug-resistance phenomena. This clinical need le
Externí odkaz:
https://doaj.org/article/e4bc0e012fad477e8c913249d65644d3
Autor:
Francesca Carofiglio, Daniela Trisciuzzi, Nicola Gambacorta, Francesco Leonetti, Angela Stefanachi, Orazio Nicolotti
Publikováno v:
Molecules, Vol 25, Iss 18, p 4210 (2020)
The fusion oncoprotein Bcr-Abl is an aberrant tyrosine kinase responsible for chronic myeloid leukemia and acute lymphoblastic leukemia. The auto-inhibition regulatory module observed in the progenitor kinase c-Abl is lost in the aberrant Bcr-Abl, be
Externí odkaz:
https://doaj.org/article/21b28454d2694050bbe168398f25d3ed
Autor:
Francesca Carofiglio, Antonio Lopalco, Angela Lopedota, Annalisa Cutrignelli, Orazio Nicolotti, Nunzio Denora, Angela Stefanachi, Francesco Leonetti
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4469 (2020)
The therapeutic approach to Chronic Myeloid Leukemia (CML) has changed since the advent of the tyrosine kinase inhibitor (TKI) imatinib, which was then followed by the second generation TKIs dasatinib, nilotinib, and, finally, by ponatinib, a third-g
Externí odkaz:
https://doaj.org/article/5a7187f1847e4e928e7da6fca5ec71b1
Autor:
Ilenia Giangreco, Gianluca Lattanzi, Orazio Nicolotti, Marco Catto, Antonio Laghezza, Francesco Leonetti, Angela Stefanachi, Angelo Carotti
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25597 (2011)
Matrix metalloproteinases (MMP) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-apoptotic ligands, and the release and cleavage of cell-surface receptors. Hence, th
Externí odkaz:
https://doaj.org/article/0dd6ff74dd1241729dc69a686197f111
Autor:
Francesca Serena Abatematteo, Maria Majellaro, Bianca Montsch, Rubén Prieto-Díaz, Mauro Niso, Marialessandra Contino, Angela Stefanachi, Chiara Riganti, Giuseppe Felice Mangiatordi, Pietro Delre, Petra Heffeter, Eddy Sotelo, Carmen Abate
Publikováno v:
Journal of Medicinal Chemistry. 66:3798-3817