Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Angela Saverimuthu"'
Autor:
Yiqing Xu, Yi-Ju Amy Chen, Yunhong Wu, Angela Saverimuthu, Archana Jadhav, Rehana Bhuiyan, Jason Sandler, Jiang Yio, Vivek Kumar
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveHomologous recombination (HR) comprises series of interrelated pathways that repair double-stranded DNA breaks and inter-strand crosslinks. It provides support for DNA replication to recover stalled or broken replication forks. Compared with
Externí odkaz:
https://doaj.org/article/1a0a477e86c54059a5051f17d9a12846
Autor:
Jasmine Lee, Yin-Yi Xiao, Yan Yu Sun, Jasminka Balderacchi, Bradley Clark, Jatin Desani, Vivek Kumar, Angela Saverimuthu, Khin Than Win, Yiwu Huang, Yiqing Xu
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2, and EPCAM. A non-
Externí odkaz:
https://doaj.org/article/1e9b776923ff4ba89785106aebf7f486
Autor:
Ciara C O Sullivan, Jun He, Vera J Suman, Krishna R Kalari, Roberto A Leon-Ferre, Jose C Villasboas-Bisneto, Pratima Chalasani, Demet Gokalp Yasar, Daniel M Anderson, Philip J Stella, Anthony J Jaslowski, Susan H Tannenbaum, Angela Saverimuthu, Donald Northfelt, Alvaro Moreno-Aspitia, Jodi M Carter, Minetta C Liu, Liewei Wang, Zhenkun Lou, Matthew P Goetz
Publikováno v:
Cancer Research. 82:OT2-19
Background: Although major advances have been made in the treatment of HER2+ metastatic breast cancer (MBC), the goal of care remains largely palliative, therefore better treatments are needed. Given encouraging preclinical and clinical data, the com
Autor:
Husnain Waseem, Arsalan Talib Hashmi, Stephan Kamholz, Asiya Batool, Maham Ansar, Angela Saverimuthu, Carlos Henriquez Felipe
Publikováno v:
American Journal of Therapeutics. 26:e653-e655
Autor:
Bradley Clark, Yan Yu Sun, Yiwu Huang, Jasmine Lee, Jasminka Balderacchi, Angela Saverimuthu, Jatin Karsandas Desani, Yiqing Xu, Khin Than Win, Vivek Kumar, Yin-Yi Xiao
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)
BMC Cancer
BMC Cancer
Background The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2, and EPCAM. A non-hereditar
Autor:
Robert D Kalter, Olaoluwatomi Lamikanra, Selma Demir, Edward K. Chapnick, Lawrence Wolf, Melvyn Hecht, Radhika Voleti, Kamaldeen Agoro, Angela Saverimuthu, Stephan Kamholz, Sushilkumar Satish Gupta, Michael Kantrowitz, Peter Homel, Nomsa Musemwa, Vimbai Nyemba
Publikováno v:
Journal of Clinical Medicine Research
Background: In light of rising healthcare costs and evidence of inefficient use of medical resources, there is growing interest in reducing healthcare waste by clinicians. Unwarranted lab tests may lead to further tests, prolonged hospital stays, unn
Autor:
Audrik Perez, Abhinav Saxena, Shyam Shankar, Prarthna Chandar, Angela Saverimuthu, Mangalore Amith Shenoy, Chanaka Seneviratne, Yizhak Kupfer
Publikováno v:
American journal of therapeutics. 27(3)
Autor:
Jennifer Clauson, Kevin Ritt, Matthew M. Cooney, Amy Franzen, D. Oubre, Megan Shulman, Raju Kumar Vaddepally, Ewelina Protomastro, Kimberly L. Blackwell, Minal A. Barve, Francis Mark Senecal, Angela Saverimuthu, Meghan Degele, Ian Churchill Anderson, Stephanie OLeary, Victor Priego
Publikováno v:
Journal of Clinical Oncology. 39:1563-1563
1563 Background: Clinical trials that require patients to have specific actionable mutations based on next generation sequencing (NGS) present unique problems, such as recruiting patients with rare mutations, low enrollment rates, and distance betwee