Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Angela S. Archambault"'
Autor:
Jameson P. Holloman, Sophia H. Dimas, Angela S. Archambault, Fabia Filipello, Lixia Du, Jing Feng, Yonghui Zhao, Bryan Bollman, Laura Piccio, Andrew J. Steelman, Hongzhen Hu, Gregory F. Wu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17097 (2023)
Microglia are found pathologically at all stages of multiple sclerosis (MS) lesion development and are hypothesized to contribute to both inflammatory injury and neuroprotection in the MS brain. Transient receptor potential vanilloid 4 (TRPV4) channe
Externí odkaz:
https://doaj.org/article/f81cf5d4d9fb493aa25347ce8632179b
Autor:
Chelsea R Parker Harp, Angela S Archambault, Julia Sim, Mark J Shlomchik, John H Russell, Gregory F Wu
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199694 (2018)
Recent success with B cell depletion therapies has revitalized efforts to understand the pathogenic role of B cells in Multiple Sclerosis (MS). Using the adoptive transfer system of experimental autoimmune encephalomyelitis (EAE), a murine model of M
Externí odkaz:
https://doaj.org/article/485ded0f63a5431fb7b38915fa92e06c
Autor:
Jaeu Yi, Aidan T. Miller, Angela S. Archambault, Andrew J. Jones, Tara R. Bradstreet, Sravanthi Bandla, Yu-Sung Hsu, Brian T. Edelson, You W. Zhou, Daved H. Fremont, Takeshi Egawa, Nathan Singh, Gregory F. Wu, Chyi-Song Hsieh
Publikováno v:
Sci Immunol
Both higher- and lower-affinity self-reactive CD4 + T cells are expanded in autoimmunity; however, their individual contribution to disease remains unclear. We addressed this question using peptide-MHCII chimeric antigen receptor (pMHCII-CAR) T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef9a38973fcb068512500428d859be4
https://europepmc.org/articles/PMC9867937/
https://europepmc.org/articles/PMC9867937/
Autor:
Chelsea R. Parker Harp, Aidan T. Miller, Matthew D. Cheung, Aaron J. Kilgore, Rafael S. Czepielewski, Gwendalyn J. Randolph, Jesse W. Williams, Alfred H.J. Kim, Gregory F. Wu, Patrick C. Duncker, Angela S. Archambault, Benjamin M. Segal
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance A distinct murine model of multiple sclerosis used to examine factors involved in ectopic lymphoid tissue formation during central nervous system autoimmunity reveals that infiltration and aggregation of B cells within the leptomeninges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985a3234326aa56ea890aef164c86562
http://europepmc.org/articles/PMC6883802
http://europepmc.org/articles/PMC6883802
Autor:
John H. Russell, Angela S. Archambault, Chelsea R. Parker Harp, Gregory F. Wu, Julia Sim, Mark J. Shlomchik
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199694 (2018)
PLoS ONE
PLoS ONE
Recent success with B cell depletion therapies has revitalized efforts to understand the pathogenic role of B cells in Multiple Sclerosis (MS). Using the adoptive transfer system of experimental autoimmune encephalomyelitis (EAE), a murine model of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a962430bf4c78857e02dcb7f9bd663b3
http://europepmc.org/articles/PMC6019098?pdf=render
http://europepmc.org/articles/PMC6019098?pdf=render
Autor:
Chelsea R. Parker Harp, John H. Russell, Michiko Shimoda, Gregory F. Wu, Pandelakis A. Koni, Julia Sim, Christopher Linington, Stephen T. Ferris, Angela S. Archambault, Robert Mikesell
Publikováno v:
The Journal of Immunology. 194:5077-5084
B cells are increasingly regarded as integral to the pathogenesis of multiple sclerosis, in part as a result of the success of B cell–depletion therapy. Multiple B cell–dependent mechanisms contributing to inflammatory demyelination of the CNS ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89384d7068cddbcd76d3b40e5082ee6d
https://doi.org/10.4049/jimmunol.1402236
https://doi.org/10.4049/jimmunol.1402236
Autor:
Seth D. Crosby, Brian S. Kim, Robyn S. Klein, Timothy M. Miller, Matthew D. Cain, Landon K. Oetjen, Angela S. Archambault, Taylor M. Gordon, Gregory F. Wu, Mariah L. Hoye
Publikováno v:
Immunology. 155(1)
Innate immune cells are integral to the pathogenesis of several diseases of the central nervous system (CNS), including multiple sclerosis (MS). Dendritic cells (DCs) are potent CD11c(+) antigen‐presenting cells that are critical regulators of adap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e6dac4772cfc3931bb4501143de849
https://pubmed.ncbi.nlm.nih.gov/29749614
https://pubmed.ncbi.nlm.nih.gov/29749614
Autor:
Susan M. Culican, Joseph P. Culver, Gregory F. Wu, Stacey L. Peek, Beau M. Ances, Angela S. Archambault, Adam Q. Bauer, Patrick W. Wright
Publikováno v:
Experimental neurology. 295
The basis for neuronal dysfunction following inflammatory demyelination of the central nervous system (CNS) remains poorly understood. We characterized the network response to white matter injury in the anterior visual pathway using an experimental m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6001efbae6bd81f91b335466621a0339
https://pubmed.ncbi.nlm.nih.gov/28502610
https://pubmed.ncbi.nlm.nih.gov/28502610
Autor:
Angela S. Archambault, Victor S. Harrison, David Artis, Warren J. Leonard, Gregory F. Wu, Yukinori Tanaka, Brian S. Kim, Mark C. Siracusa, Taku Kambayashi, Ali Naji, Theresa M. Leichner, Atsushi Satake
Regulatory T cells (Tregs) are a subset of CD4+ T cells with suppressive function and are critical for limiting inappropriate activation of T cells. Hence, the expansion of Tregs is an attractive strategy for the treatment of autoimmune diseases. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c74ae305f1943420dd015317ae3635
https://europepmc.org/articles/PMC5386815/
https://europepmc.org/articles/PMC5386815/
Autor:
Katharine A. Walz, Anne H. Cross, Gregory F. Wu, Jessica Koenigsknecht-Talboo, Angela S. Archambault, Bryan Bollman, Soomin Shin, David M. Holtzman, Julia Sim
Publikováno v:
Journal of Neuroimmunology. 271:8-17
Apolipoprotein E (ApoE) functions as a ligand in receptor-mediated endocytosis of lipoprotein particles and has been demonstrated to play a role in antigen presentation. To explore the contribution of ApoE during autoimmune central nervous system (CN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f0180703c7954787155521809dc899
https://doi.org/10.1016/j.jneuroim.2014.03.010
https://doi.org/10.1016/j.jneuroim.2014.03.010