Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Angela Rico De Souza"'
Autor:
Hussein Traboulsi, Angela Rico de Souza, Benoit Allard, Zahraa Haidar, Mark Sorin, Vanessa Moarbes, Elizabeth D. Fixman, James G. Martin, David H. Eidelman, Carolyn J. Baglole
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates the metabolism of xenobiotics. There is growing evidence that the AhR is implicated in physiological processes such proliferation, differentiation, and immu
Externí odkaz:
https://doaj.org/article/46997e38ceb24f3687f8d078a902935b
Autor:
Angela Rico de Souza, Hussein Traboulsi, Xinyu Wang, Jorg H. Fritz, David H. Eidelman, Carolyn J. Baglole
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cigarette smoke is a prevalent respiratory toxicant that remains a leading cause of death worldwide. Cigarette smoke induces inflammation in the lungs and airways that contributes to the development of diseases such as lung cancer and chronic obstruc
Externí odkaz:
https://doaj.org/article/7685248d78c54094b73bf355479fc184
Autor:
Michela Zago, Jared A Sheridan, Parameswaran Nair, Angela Rico de Souza, Imed-Eddine Gallouzi, Simon Rousseau, Sergio Di Marco, Qutayba Hamid, David H Eidelman, Carolyn J Baglole
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74953 (2013)
The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor that responds to man-made environmental toxicants, has emerged as an endogenous regulator of cyclooxygenase-2 (Cox-2) by a mechanism that is poorly understood. In this study
Externí odkaz:
https://doaj.org/article/f44ec1b44af94398a96835d66783b8a3
Autor:
José A. Morais, Tanja Taivassalo, Russell T. Hepple, Angela Rico de Souza, Sarah K. Burke, Trace Thome, Vijayendran Chandran, Carolyn J. Baglole, Alexander John Willms, R. Thomas Jagoe, Jean Bourbeau, Maria-Eleni Anagnostou, Yana Goddard, Kayla Miguez, Liam F. Fitzgerald, Terence E. Ryan
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 589-604 (2022)
Background Chronic obstructive pulmonary disease (COPD) patients exhibit skeletal muscle atrophy, denervation, and reduced mitochondrial oxidative capacity. Whilst chronic tobacco smoke exposure is implicated in COPD muscle impairment, the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61df3176d28d17a03e3ec4c5c1a0ccc9
https://doaj.org/article/56c74ac6a0ff4894a08db077f551a387
https://doaj.org/article/56c74ac6a0ff4894a08db077f551a387
Autor:
Jean Bourbeau, Patricia J. Sime, Michela Zago, Wan C. Tan, M. Obeidat, Parameswaran Nair, Qutayba Hamid, Corry-Anke Brandsma, Annette Robichaud, Benjamin M. Smith, Thomas H. Thatcher, Angela Rico de Souza, Richard P. Phipps, David H. Eidelman, Andrea Benedetti, Don D. Sin, Yohan Bossé, Swati Pareek, Jun Ding, Leora Simon, Necola Guerrina, Carolyn J. Baglole, David C. Nickle, Hussein Traboulsi, Pei Z. Li
Publikováno v:
FASEB J
FASEB Journal, 35(3):21376. FEDERATION AMER SOC EXP BIOL
FASEB Journal, 35(3):21376. FEDERATION AMER SOC EXP BIOL
Emphysema, a component of chronic obstructive pulmonary disease (COPD), is characterized by irreversible alveolar destruction that results in a progressive decline in lung function. This alveolar destruction is caused by cigarette smoke, the most imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f41cd7b9a4e41e4b10bdfe53e22f72
https://doi.org/10.1096/fj.202002350r
https://doi.org/10.1096/fj.202002350r
Autor:
Mylène Aubertin-Leheudre, R. Thomas Jagoe, Jean Bourbeau, Tanja Taivassalo, Paul Rozakis, Vita Sonjak, Daren Elkrief, Sophia Kapchinsky, Russell T. Hepple, Charlotte H. Pion, Kayla Miguez, Angela Rico de Souza, Sudhakar Aare, Carolyn J. Baglole, Norah J. MacMillan, Madhusudanarao Vuda, Jacinthe Baril, José A. Morais
Publikováno v:
The Journal of Physiology. 596:2865-2881
Key points Chronic obstructive pulmonary disease (COPD) is largely caused by smoking, and patient limb muscle exhibits a fast fibre shift and atrophy. We show that this fast fibre shift is associated with type grouping, suggesting recurring cycles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed6462f88adb179df9b9eef04573891f
https://doi.org/10.1113/jp275558
https://doi.org/10.1113/jp275558
Autor:
Carolyn J. Baglole, Angela Rico de Souza, Benoit Allard, Swati Pareek, Hussein Traboulsi, David H. Eidelman
Publikováno v:
Molecular immunology. 114
Inflammation is a response to injury and infection. Although protective under physiological conditions, excessive and persistent inflammation is linked to numerous diseases. As the lungs are continuously exposed to the external environment, the respi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b769524afd0ac447eaeca2d90572308
https://pubmed.ncbi.nlm.nih.gov/31476634
https://pubmed.ncbi.nlm.nih.gov/31476634
Pulmonary and diaphragmatic pathology in collagen type I α1 mutant mice with osteogenesis imperfecta
Autor:
Basil J. Petrof, Hussein Traboulsi, Frank Rauch, Christian Giordano, Carolyn J. Baglole, Angela Rico de Souza, Feng Liang, Josephine T. Tauer
Publikováno v:
Pediatric research. 83(6)
BackgroundOsteogenesis imperfecta (OI) is most often caused by mutations in type I collagen genes. Respiratory complications have been largely attributed to spine and ribcage deformities. We hypothesized that direct involvement of the pulmonary paren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5d2b95560c40c92df55d638d40a260
https://pubmed.ncbi.nlm.nih.gov/29538357
https://pubmed.ncbi.nlm.nih.gov/29538357
Autor:
Alvin Gomez, Angela Rico de Souza, Matthew Iu, Sarah Rogers, Michela Zago, Carolyn J. Baglole, Necola Guerrina, Jason Matthews
Publikováno v:
Scientific Reports
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically known for its toxic responses to man-made pollutants such as dioxin. More recently, the AhR has emerged as a suppressor of inflammation, oxidative stress and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935591cfe5985af1e2256e0f6c21b4d8
Autor:
Matthew Iu, Angela Rico de Souza, Qutayba Hamid, John H. White, Swati Pareek, David H. Eidelman, Carolyn J. Baglole, Manuella Bouttier, Michela Zago
Publikováno v:
Free radical biologymedicine. 108
Chronic obstructive pulmonary disease (COPD) is a chronic and prevalent respiratory disease caused primarily by long term inhalation of cigarette smoke. A major hallmark of COPD is elevated apoptosis of structural lung cells including fibroblasts. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f232059428199e2949f84397ffdefc35
https://pubmed.ncbi.nlm.nih.gov/28254546
https://pubmed.ncbi.nlm.nih.gov/28254546