The air-gap PAD: a roll-to-roll-compatible fabrication method for paper microfluidics

Autor: Rachel M. Roller, Angela Rea, Marya Lieberman

Publikováno v: Lab on a Chip. 23:1918-1925

The air-gap design enables large-scale roll-to-roll manufacturing of paper microfluidic devices.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f77836deb926a5939e16913bff068785
https://doi.org/10.1039/d2lc01164f

Versatile cationic lipids for siRNA delivery

Autor: Casey Pence, Majed Matar, David Ulkoski, Leslie Wilkinson, Jason G. Fewell, Elaine Brunhoeber, Kirby Wallace, Diane McClure, Gregory Slobodkin, Jennifer Rice, Richard Congo, Angela Rea-Ramsey, Kevin Polach, Jeff Sparks, Khursheed Anwer

Publikováno v: Journal of Controlled Release. 158:269-276

Exploitation of the RNA interference (RNAi) pathway offers the promise of new and effective therapies for a wide variety of diseases. Clinical development of new drugs based on this platform technology is still limited, however, by a lack of safe and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e747ab08c4767a422cd56f84ba579ae4
https://doi.org/10.1016/j.jconrel.2011.11.006

Flow and adhesion of drug carriers in blood vessels depend on their shape: A study using model synthetic microvascular networks

Autor: Balabhaskar Prabhakarpandian, Samir Mitragotri, Kapil Pant, Angela Rea-Ramsey, Nishit Doshi, Shivshankar Sundaram

Publikováno v: Journal of Controlled Release. 146:196-200

Development of novel carriers and optimization of their design parameters has led to significant advances in the field of targeted drug delivery. Since carrier shape has recently been recognized as an important design parameter for drug delivery, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bba267c17e89212b94c051a0f1d3a99
https://doi.org/10.1016/j.jconrel.2010.04.007

Delivery of siRNA to the mouse lung via a functionalized lipopolyamine

Autor: Anke Geick, Kerstin Jahn-Hofmann, Monika Krampert, Jennifer Rice, Andrea Schuster, Khursheed Anwer, Richard Congo, Hans-Peter Vornlocher, Gregory Slobodkin, Jason G. Fewell, Diane McClure, Matthias John, Jeff Sparks, Angela Rea-Ramsey, Kevin Polach, Majed Matar, Elaine Brunhoeber

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy. 20(1)

We have designed a series of versatile lipopolyamines which are amenable to chemical modification for in vivo delivery of small interfering RNA (siRNA). This report focuses on one such lipopolyamine (Staramine), its functionalized derivatives and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4d447681d45dce4a2223b795d8d66a
https://pubmed.ncbi.nlm.nih.gov/21988874

Simian immunodeficiency virus Vpr/Vpx proteins kill bystander noninfected CD4+T-lymphocytes by induction of apoptosis

Autor: Y. Chebloune, Opendra Narayan, Stephanie Villet, Thierry Morin, François Guiguen, Angela Rea, Amel Baya Bouzar, Laurent Genestier, Jean Francois Mornex, Céline Garnier

Publikováno v: Virology
Virology, Elsevier, 2004, 326 (1), pp.47-56. ⟨10.1016/j.virol.2004.05.016⟩
Virology, 2004, 326 (1), pp.47-56. ⟨10.1016/j.virol.2004.05.016⟩

International audience; The depletion of CD4+ T-lymphocytes central to the immunodeficiency in acquired immunodeficiency syndrome (AIDS) is largely mediated by apoptosis of both infected and uninfected cells, but the mechanisms involved and the viral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915640f44266b91061cf551c975a7c7b
https://hal.inrae.fr/hal-02679433