Výsledky vyhledávání - "Angela Rankin"

PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways

Autor: Chris I. Jones, Willem H. Ouwehand, William J. Kaiser, Alison H. Goodall, Angela Rankin, Jonathan M. Gibbins, Leonardo A. Moraes, Stephen F. Garner

Publikováno v: Febs Letters

Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits platelet response to collagen and may also inhibit two other major platelet agonists ADP and thrombin although this has been less well explored. We hypothesized that the combined effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcb5142cd3ffde78f033b0b3656cdab
https://doi.org/10.1016/j.febslet.2009.10.037

Zobrazit plný text záznamu

Alloantibodies against low-frequency human platelet antigens do not account for a significant proportion of cases of fetomaternal alloimmune thrombocytopenia: evidence from 1054 cases

Autor: Deborah J. Smyth, Elly Huiskes, Sarah Nutland, Cedric Ghevaert, L. Porcelijn, Graham A. Smith, Kaija Javela, Tamam Bakchoul, Sentot Santoso, Angela Rankin, Simon McBride, Nicholas A. Watkins, Willem H. Ouwehand, Riitta Kekomäki

Publikováno v: Transfusion. 49:2084-2089

BACKGROUND: Maternal alloantibodies against the five common human platelet antigen (HPA) systems (HPA-1 to -3, -5, and -15) are found in only 20% of cases referred for fetal and neonatal thrombocytopenia (FMAIT) investigations. The question asked was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f81be3fae5960bd7ea0fd661cd5047
https://doi.org/10.1111/j.1537-2995.2009.02246.x

Zobrazit plný text záznamu

Severe fetomaternal alloimmune thrombocytopenia due to anti-human platelet antigen (HPA)-1a in a mother with a rare and silenced ITGB3*0101 (GPIIIa) allele

Autor: C. Cheetham-Wilkinson, Graham A. Smith, Angela Rankin, E. Ranasinghe, Nicholas A. Watkins, C. Riddle, Willem H. Ouwehand

Publikováno v: Vox Sanguinis. 93:325-330

Background and Objectives Fetomaternal alloimmune thrombocytopenia (FMAIT) is caused by maternal antibodies against a human platelet antigen (HPA) present on fetal, but absent from maternal platelets. We identified and characterized a case of FMAIT d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6b22b2cdd189b52053c0f1a521b5e06
https://doi.org/10.1111/j.1423-0410.2007.00968.x

Zobrazit plný text záznamu

Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus

Autor: Alison H. Goodall, Stephen F. Garner, Frank Dudbridge, John Hogwood, Chris I. Jones, Brian D. M. Tom, J. Walton, Richard W. Farndale, Angela Rankin, Carlo Berzuini, W. Angenent, Jonathan Stephens, Willem H. Ouwehand, Philippa Burns, A. Bernard

Publikováno v: Journal of Thrombosis and Haemostasis. 5:1756-1765

BACKGROUND: Evidence suggests the wide variation in platelet response within the population is genetically controlled. Unraveling the complex relationship between sequence variation and platelet phenotype requires accurate and reproducible measuremen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcdad6b425256ac747db148c6d13d91
https://doi.org/10.1111/j.1538-7836.2007.02632.x

Zobrazit plný text záznamu

A naturally occurring Leu33Val mutation in beta3-integrin impairs the HPA-1a epitope: the third allele of HPA-1

Autor: Hartmut Kroll, Evelyne Kretzschmar, Willem H. Ouwehand, Cornelia L. Andrei-Selmer, Sentot Santoso, Angela Rankin, Ines Socher, Nicholas A. Watkins

Publikováno v: Transfusion. 46:790-799

BACKGROUND: Single-amino-acid substitution Leu33Pro in the β3-integrin is responsible for the formation of the human platelet antigen (HPA)-1. Alloimmunization against HPA-1a (β3-Leu33) is the most frequent cause of neonatal alloimmune thrombocytop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c408aca5a3d5a5974f83dd5088f5800
https://doi.org/10.1111/j.1537-2995.2006.00797.x

Zobrazit plný text záznamu

How do you reward your long-standing aesthetic clients?

Autor: Samantha Scott, Deborah Vine, Jan Birch, Angela Rankin, Marcelle Schulz

Publikováno v: Journal of Aesthetic Nursing. 5:204-205

Every sector caters to people with different needs, requiring business owners to know as much as possible about their target audience and make a concerted effort to not only meet, but also exceed their expectations. In the third instalment of this pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65ceb9b657aedc5fe56f87c5a44ab7a7
https://doi.org/10.12968/joan.2016.5.4.204

Zobrazit plný text záznamu

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression

Autor: Catherine M. Onley, Nicholas A. Watkins, Richard W. Farndale, Peter A. Smethurst, Lotta Joutsi-Korhonen, Willem H. Ouwehand, Elaine Gray, Philip G. de Groot, Lorna M. Williamson, Alison H. Goodall, Angela Rankin, Martin J. W. IJsseldijk

Publikováno v: Blood. 101:4372-4379

Interaction of platelets with collagen under conditions of blood flow is a multi-step process with tethering via glycoprotein IbIXV (GPIbIXV) over von Willebrand factor, adhesion by direct interaction with the integrin GPIaIIa, and signaling via GPVI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeb6440c8dc830656f469e59b53a221
https://doi.org/10.1182/blood-2002-08-2591

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání