Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Angela R. Parrish"'
Autor:
Angela R. Parrish, Yuguo Ma, Vanessa K. Lacey, Steven P. Briggs, Shuliang Han, Zhouxin Shen, Lei Wang
Publikováno v:
Angewandte Chemie International Edition. 50:8692-8696
The ability to monitor phosphorylation events can provide valuable information pertaining to signal transduction regulation and for developing effective therapeutics targeted at aberrant kinase activities.[1] Kinase activity can be optically reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971396e209f22051fb6ed5d6fbdffeda
https://doi.org/10.1002/anie.201102923
https://doi.org/10.1002/anie.201102923
Publikováno v:
Carcinogenesis. 31:1124-1131
Deregulated estrogen signaling is evidently linked to breast cancer pathophysiology, although the role of signal transducer and activator of transcription (Stat)5a, integral to normal mammary gland development, is less clear. A mouse model of mammary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33558a7ebebb03794bc82a9e77c5c211
https://doi.org/10.1093/carcin/bgq048
https://doi.org/10.1093/carcin/bgq048
Autor:
Xingyu She, Steven P. Briggs, Irene Coin, Andrew Dillin, Zhouxin Shen, Lei Wang, Angela R. Parrish, Zheng Xiang
Publikováno v:
ACS chemical biology. 7(7)
The genetic code specifies 20 common amino acids and is largely preserved in both single and multicellular organisms. Unnatural amino acids (Uaas) have been genetically incorporated into proteins by using engineered orthogonal tRNA/aminoacyl-tRNA syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa9d1df4ee13b2e8a6f8ba5d981576e
https://pubmed.ncbi.nlm.nih.gov/22554080
https://pubmed.ncbi.nlm.nih.gov/22554080
Autor:
Lei Wang, Angela R. Parrish
Co-opting endogenous protein translational machinery and introducing an orthogonal tRNA/aminoacyl-tRNA synthetase pair that recognizes a unique codon enables the site-specific incorporation of unnatural amino acids into proteins in live cells with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6e6e58be6156a958c715857865b497
https://doi.org/10.1016/b978-008045382-8.00694-8
https://doi.org/10.1016/b978-008045382-8.00694-8
Publikováno v:
Chemistrybiology. 16(3)
SummaryUsing an orthogonal tRNA-synthetase pair, unnatural amino acids can be genetically encoded with high efficiency and fidelity, and over 40 unnatural amino acids have been site-specifically incorporated into proteins in Escherichia coli, yeast,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b156a3aec4d7ec4fabd0f95cb8d426b
https://pubmed.ncbi.nlm.nih.gov/19318213
https://pubmed.ncbi.nlm.nih.gov/19318213
Autor:
Michael D. Johnson, Maddalena T. Tilli, Ion Cotarla, Angela R. Parrish, Priscilla A. Furth, Laundette P. Jones
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 21 (2008)
BMC Cancer
BMC Cancer
Background Genetically engineered mouse models of mammary gland cancer enable the in vivo study of molecular mechanisms and signaling during development and cancer pathophysiology. However, traditional whole mount and histological imaging modalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80eb8e0eb95906945db4fb1d43047d4b
http://www.biomedcentral.com/1471-2407/8/21
http://www.biomedcentral.com/1471-2407/8/21
Autor:
M Carla Cabrera, Mary K. Sidawy, Priscilla A. Furth, Angela R. Parrish, Ann L. Gallagher, Maddalena T. Tilli, Kathleen M. Torre, Erini Makariou, Minetta C. Liu, Sandra A. Polin
Publikováno v:
Journal of biomedical optics. 12(5)
Real-time technologies can increase the efficiency of obtaining informative biopsies and accelerate interpretation of biopsy pathological review. Cellular aberrations inherent to cancer cells, including nuclear size, can currently be detected, but fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d2dce560c441a40ca734e6a39e9476
https://pubmed.ncbi.nlm.nih.gov/17994884
https://pubmed.ncbi.nlm.nih.gov/17994884
Autor:
Laundette P. Jones, Ewa D. Halama, Maddalena T. Tilli, Eliot M. Rosen, S Assefnia, Kathleen M. Torre, Angela R. Parrish, Priscilla A. Furth
BRCA1 can regulate estrogen receptor-alpha (ERalpha) activity. This study tested the hypotheses that Brca1 loss in mammary epithelium alters the estrogenic growth response and that exposure to increased estrogen or ERalpha collaborates with Brca1 def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c018ff17cbd9f960feb0f5ba6ca031
https://europepmc.org/articles/PMC3045705/
https://europepmc.org/articles/PMC3045705/
Publikováno v:
Current opinion in neurobiology. 16(5)
The design and manipulation of proteins has created many tools that have become popular in neurobiological studies, and new developments in protein science will be the fuel for future research. Genetically encoded protein-based biosensors have been d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f752d2e80a6784468f5645c7c5f0a55c
https://pubmed.ncbi.nlm.nih.gov/16956756
https://pubmed.ncbi.nlm.nih.gov/16956756
Autor:
Maddalena T. Tilli, M. Carla Cabrera, Angela R. Parrish, Kathleen M. Torre, Mary K. Sidawy, Ann L. Gallagher, Erini Makariou, Sandra A. Polin, Minetta C. Liu, Priscilla A. Furth
Publikováno v:
Journal of Biomedical Optics; Sep2007, Vol. 12 Issue 5, p05190-05190, 1p