Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Angela R. Omilian"'
Autor:
Angela R. Omilian, Rikki Cannioto, Lucas Mendicino, Leighton Stein, Wiam Bshara, Bo Qin, Elisa V. Bandera, Nur Zeinomar, Scott I. Abrams, Chi-Chen Hong, Song Yao, Thaer Khoury, Christine B. Ambrosone
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Background Tumor-associated macrophages (TAMs) are a prominent immune subpopulation in the tumor microenvironment that could potentially serve as therapeutic targets for breast cancer. Thus, it is important to characterize this cell populati
Externí odkaz:
https://doaj.org/article/6f527a7fa43b4abe837920ef9add5330
Autor:
Mmadili N. Ilozumba, Song Yao, Adana A. M. Llanos, Angela R. Omilian, Weizhou Zhang, Susmita Datta, Chi-Chen Hong, Warren Davis, Thaer Khoury, Elisa V. Bandera, Michael Higgins, Christine B. Ambrosone, Ting-Yuan David Cheng
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Aberrant activation of the mammalian Target of Rapamycin (mTOR) pathway has been linked to obesity and endocrine therapy resistance, factors that may contribute to Black-White disparities in breast cancer outcomes. We evaluated as
Externí odkaz:
https://doaj.org/article/aa74f73f590449e0b3b90be0c1d170ee
Autor:
Angela R. Omilian, Haiyang Sheng, Chi‐Chen Hong, Elisa V. Bandera, Thaer Khoury, Christine B. Ambrosone, Song Yao
Publikováno v:
Molecular Oncology, Vol 16, Iss 1, Pp 54-68 (2022)
The NanoString GeoMx digital spatial profiling is a new multiplexed platform that quantifies the abundance of tumor‐ and immune‐related proteins in a spatially resolved manner. We performed DSP for the simultaneous assessment of 52 analytes withi
Externí odkaz:
https://doaj.org/article/428d4e276c9f4cafb6ba75ebac302684
Autor:
Ting-Yuan David Cheng, Angela R. Omilian, Song Yao, Weizhou Zhang, Susmita Datta, Wiam Bshara, Rochelle Payne Ondracek, Warren Davis, Song Liu, Chi-Chen Hong, Elisa V. Bandera, Thaer Khoury, Christine B. Ambrosone
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Background The mechanistic target of rapamycin (mTOR) pathway promoted by positive energy imbalance and insulin-like growth factors can be a mechanism by which obesity influences breast cancer risk. We evaluated the associations of body fatn
Externí odkaz:
https://doaj.org/article/998df8435a9742a3bb4e7e2d04cc07c9
Autor:
Yara Abdou, Kristopher Attwood, Ting-Yuan David Cheng, Song Yao, Elisa V. Bandera, Gary R. Zirpoli, Rochelle Payne Ondracek, Leighton Stein, Wiam Bshara, Thaer Khoury, Christine B. Ambrosone, Angela R. Omilian
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background African American/Black women with breast cancer have poorer survival than White women, and this disparity persists even after adjusting for non-biological factors. Differences in tumor immune biology have been reported between Bla
Externí odkaz:
https://doaj.org/article/5521d84d9f534f85b96be86841981b66
Autor:
Adana A. M. Llanos, Yong Lin, Wenjin Chen, Song Yao, Jorden Norin, Marina A. Chekmareva, Coral Omene, Lei Cong, Angela R. Omilian, Thaer Khoury, Chi-Chen Hong, Shridar Ganesan, David J. Foran, Michael Higgins, Christine B. Ambrosone, Elisa V. Bandera, Kitaw Demissie
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-16 (2020)
Abstract Background The molecular mechanisms underlying the association between increased adiposity and aggressive breast cancer phenotypes remain unclear, but likely involve the adipokines, leptin (LEP) and adiponectin (ADIPOQ), and their receptors
Externí odkaz:
https://doaj.org/article/1380d7cb36394a49a6c3cddcb0b2a0d1
Autor:
Jennifer M. Mongiovi, Chi-Chen Hong, Gary R. Zirpoli, Thaer Khoury, Angela R. Omilian, Bo Qin, Elisa V. Bandera, Song Yao, Christine B. Ambrosone, Zhihong Gong
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
COX and ALOX genes are involved in inflammatory processes and that may be related to breast cancer risk differentially between White and Black women. We evaluated distributions of genetic variants involved in COX2 and ALOX-related pathways and examin
Externí odkaz:
https://doaj.org/article/ce1b4c8befe947feb42642249cff0c40
Autor:
Lei Wei, Antonios Papanicolau-Sengos, Song Liu, Jianmin Wang, Jeffrey M. Conroy, Sean T. Glenn, Elizabeth Brese, Qiang Hu, Kiersten Marie Miles, Blake Burgher, Maochun Qin, Karen Head, Angela R. Omilian, Wiam Bshara, John Krolewski, Donald L. Trump, Candace S. Johnson, Carl D. Morrison
Publikováno v:
BMC Medical Genomics, Vol 9, Iss 1, Pp 1-10 (2016)
Abstract Background The rapid adoption of next-generation sequencing provides an efficient system for detecting somatic alterations in neoplasms. The detection of such alterations requires a matched non-neoplastic sample for adequate filtering of non
Externí odkaz:
https://doaj.org/article/b68b8cd9e13241639297e3c8e5073532
Autor:
Joseph A. Wawrzyniak, Anna Bianchi-Smiraglia, Wiam Bshara, Sudha Mannava, Jeff Ackroyd, Archis Bagati, Angela R. Omilian, Michael Im, Natalia Fedtsova, Jeffrey C. Miecznikowski, Kalyana C. Moparthy, Shoshanna N. Zucker, Qianqian Zhu, Nadezhda I. Kozlova, Albert E. Berman, Keith S. Hoek, Andrei V. Gudkov, Donna S. Shewach, Carl D. Morrison, Mikhail A. Nikiforov
Publikováno v:
Cell Reports, Vol 5, Iss 2, Pp 493-507 (2013)
Melanoma is one of the most aggressive types of human cancers, and the mechanisms underlying melanoma invasive phenotype are not completely understood. Here, we report that expression of guanosine monophosphate reductase (GMPR), an enzyme involved in
Externí odkaz:
https://doaj.org/article/778f0726387c4d02b68bac1250ad63c9
Autor:
Henry Garcia, Jeffrey C. Miecznikowski, Alfiya Safina, Mairead Commane, Anja Ruusulehto, Sami Kilpinen, Robert W. Leach, Kristopher Attwood, Yan Li, Seamus Degan, Angela R. Omilian, Olga Guryanova, Olympia Papantonopoulou, Jianmin Wang, Michael Buck, Song Liu, Carl Morrison, Katerina V. Gurova
Publikováno v:
Cell Reports, Vol 4, Iss 1, Pp 159-173 (2013)
The facilitates chromatin transcription (FACT) complex is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT was previously considered to be ubiquitously expressed and not associated with any disease. However, we
Externí odkaz:
https://doaj.org/article/8bd40d907b0c415691d9ba1feb1b2b14