Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Angela R. Garcia"'
Autor:
Miguel Chenlo, Iria A. Rodriguez-Gomez, Ramon Serramito, Angela R. Garcia-Rendueles, Rocío Villar-Taibo, Eva Fernandez-Rodriguez, Sihara Perez-Romero, Maria Suarez-Fariña, Alfredo Garcia-Allut, Jose M. Cabezas-Agricola, Javier Rodriguez-Garcia, Pamela V. Lear, Rosa M. Alvarez-San Martin, Cristina Alvarez-Escola, Ignacio Bernabeu, Clara V. Alvarez
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 537-552 (2019)
Background: Acromegaly is produced by excess growth hormone secreted by a pituitary adenoma of somatotroph cells (ACRO). First-line therapy, surgery and adjuvant therapy with somatostatin analogs, fails in 25% of patients. There is no predictive fact
Externí odkaz:
https://doaj.org/article/18978d90c30642d6a6cfc6c540bef848
Autor:
Amanda J Lea, Andrew G Clark, Andrew W Dahl, Orrin Devinsky, Angela R Garcia, Christopher D Golden, Joseph Kamau, Thomas S Kraft, Yvonne A L Lim, Dino J Martins, Donald Mogoi, Päivi Pajukanta, George H Perry, Herman Pontzer, Benjamin C Trumble, Samuel S Urlacher, Vivek V Venkataraman, Ian J Wallace, Michael Gurven, Daniel E Lieberman, Julien F Ayroles
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002311 (2023)
Noncommunicable diseases (NCDs) are on the rise worldwide. Obesity, cardiovascular disease, and type 2 diabetes are among a long list of "lifestyle" diseases that were rare throughout human history but are now common. The evolutionary mismatch hypoth
Externí odkaz:
https://doaj.org/article/2745ad47e80c435daa7ab7fa5ed0c557
Autor:
Angela R Garcia, Caleb Finch, Margaret Gatz, Thomas Kraft, Daniel Eid Rodriguez, Daniel Cummings, Mia Charifson, Kenneth Buetow, Bret A Beheim, Hooman Allayee, Gregory S Thomas, Jonathan Stieglitz, Michael D Gurven, Hillard Kaplan, Benjamin C Trumble
Publikováno v:
eLife, Vol 10 (2021)
In post-industrial settings, apolipoprotein E4 (APOE4) is associated with increased cardiovascular and neurological disease risk. However, the majority of human evolutionary history occurred in environments with higher pathogenic diversity and low ca
Externí odkaz:
https://doaj.org/article/0a3db5e60d954d4f846826abf855dc08
Autor:
Adrian V Jaeggi, Aaron D Blackwell, Christopher von Rueden, Benjamin C Trumble, Jonathan Stieglitz, Angela R Garcia, Thomas S Kraft, Bret A Beheim, Paul L Hooper, Hillard Kaplan, Michael Gurven
Publikováno v:
eLife, Vol 10 (2021)
In high-income countries, one’s relative socio-economic position and economic inequality may affect health and well-being, arguably via psychosocial stress. We tested this in a small-scale subsistence society, the Tsimane, by associating relative h
Externí odkaz:
https://doaj.org/article/5d23e88c6fbf486e84922e742c0f4217
Autor:
Hillard Kaplan, Paul L. Hooper, Margaret Gatz, Wendy J. Mack, E. Meng Law, Helena C. Chui, M. Linda Sutherland, James D. Sutherland, Christopher J. Rowan, L. Samuel Wann, Adel H. Allam, Randall C. Thompson, David E. Michalik, Guido Lombardi, Michael I. Miyamoto, Daniel Eid Rodriguez, Juan Copajira Adrian, Raul Quispe Gutierrez, Bret A. Beheim, Daniel K. Cummings, Edmond Seabright, Sarah Alami, Angela R. Garcia, Kenneth Buetow, Gregory S. Thomas, Caleb E. Finch, Jonathan Stieglitz, Benjamin C. Trumble, Michael D. Gurven, Andrei Irimia
Little is known about brain aging or dementia in nonindustrialized environments that are similar to how humans lived throughout evolutionary history. This paper examines brain volume (BV) in middle and old age among two indigenous South American popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff668eda17a369831e0ab212ec5b9b1
https://hdl.handle.net/20.500.12866/13357
https://hdl.handle.net/20.500.12866/13357
Autor:
Angela R Garcia, Yih‐Kuang Lu, Margaret Gatz, Daniel Eid Rodriguez, Raul Quispe Gutierrez, Juan J Copajira Adrian, Jesus Bani Cuata, M Linda Sutherland, James D Sutherland, Daniel K Cummings, Thomas Kraft, Wendy J Mack, Helena C Chui, Meng Law, Giuseppe Barisano, Amy R Borenstein, Andrei Irimia, Ellen E Walters, Gregory S Thomas, Randall C Thompson, Michael I Miyamoto, David E Michalik, L Samuel Wann, Adel H Allam, Christopher J Rowan, Heather M Highland, Kari E North, Caleb E Finch, Jonathan Stieglitz, Michael D Gurven, Benjamin C Trumble, Hillard Kaplan, Kenneth Buetow
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Margaret Gatz, Wendy J. Mack, Helena C. Chui, E. Meng Law, Giuseppe Barisano, M. Linda Sutherland, James D. Sutherland, Daniel Eid Rodriguez, Raul Quispe Gutierrez, Juan Copajira Adrian, Jesus Bani Cuata, Amy R. Borenstein, Ellen E. Walters, Andrei Irimia, Christopher J. Rowan, L. Samuel Wann, Adel H. Allam, Randall C. Thompson, Michael I. Miyamoto, David E. Michalik, Daniel K. Cummings, Edmond Seabright, Angela R. Garcia, Paul L. Hooper, Thomas S. Kraft, Caleb E. Finch, Gregory S. Thomas, Jonathan Stieglitz, Benjamin C. Trumble, Michael D. Gurven, Hillard Kaplan
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 19, iss 1
IntroductionWe evaluated the prevalence of dementia and mild cognitive impairment (MCI) in indigenous Tsimane and Moseten, who lead a subsistence lifestyle.MethodsParticipants from population-based samples ≥60 years of age (n=623) were assessed usi
Autor:
Margaret Gatz, Andrei Irimia, Maria Calvillo, Caleb E. Finch, Hillard Kaplan, Adel H. Allam, David J. Robles, Edmond Seabright, Angela R. Garcia, James D. Sutherland, L. Samuel Wann, Wendy J. Mack, Benjamin C. Trumble, Van Anh Ngo, Sarah Alami, Gregory S. Thomas, E. Meng Law, Nahian F. Chowdhury, Randall C. Thompson, Chris J. Rowan, Alexander S. Maher, Kenneth A. Rostowsky, Paul L. Hooper, Daniel K. Cummings, Michael Gurven, M. Linda Sutherland, David E. Michalik, Nikhil N. Chaudhari, Jonathan Stieglitz
Publikováno v:
J Gerontol A Biol Sci Med Sci
The journals of gerontology. Series A, Biological sciences and medical sciences, vol 76, iss 12
The journals of gerontology. Series A, Biological sciences and medical sciences, vol 76, iss 12
Brain atrophy is correlated with risk of cognitive impairment, functional decline, and dementia. Despite a high infectious disease burden, Tsimane forager-horticulturists of Bolivia have the lowest prevalence of coronary atherosclerosis of any studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db9db779b439c31d15fbfb171f37e27
http://iast.fr/pub/125650
http://iast.fr/pub/125650
Autor:
Hillard Kaplan, Kenneth H. Buetow, Thomas S. Kraft, Hooman Allayee, Caleb E. Finch, Michael Gurven, Angela R. Garcia, Bret Alexander Beheim, Mia Charifson, Daniel Cummings, Daniel Eid Rodriguez, Gregory S. Thomas, Benjamin C. Trumble, Margaret Gatz, Jonathan Stieglitz
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2021, pp.1-20. ⟨10.7554/eLife.68231⟩
eLife, Vol 10 (2021)
eLife, eLife Sciences Publication, 2021, pp.1-20. ⟨10.7554/eLife.68231⟩
eLife, Vol 10 (2021)
In post-industrial settings, apolipoprotein E4 (APOE4) is associated with increased cardiovascular and neurological disease risk. However, the majority of human evolutionary history occurred in environments with higher pathogenic diversity and low ca
Autor:
Arnaud Obri, Angela R. Garcia-Rendueles, Giuseppe D'Agostino, Bence Rácz, Iñigo Chivite, Marc Schneeberger, Mehdi Boutagouga Boudjadja, Maria Milà-Guasch, Pau Gama-Perez, Ramon Gomis, Roberta Haddad-Tóvolli, Antonio Zorzano, Maria Teresa Alonso, Jordi Altirriba, Jonathan Rojo-Ruiz, Luis Varela, Tamas L. Horvath, Clara V. Alvarez, Monica Imbernon, Pablo M. Garcia-Roves, Alicia G. Gómez-Valadés, Marc Claret, Elena Eyre, Sara Ramírez, Rubén Nogueiras, Macarena Pozo
Publikováno v:
Cell Metabolism
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Gómez-valadés, A G, Pozo, M, Varela, L, Boudjadja, M B, Ramírez, S, Chivite, I, Eyre, E, Haddad-tóvolli, R, Obri, A, Milà-guasch, M, Altirriba, J, Schneeberger, M, Imbernón, M, Garcia-rendueles, A R, Gama-perez, P, Rojo-ruiz, J, Rácz, B, Alonso, M T, Gomis, R, Zorzano, A, D’agostino, G, Alvarez, C V, Nogueiras, R, Garcia-roves, P M, Horvath, T L & Claret, M 2021, ' Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis ', Cell Metabolism, vol. 33, no. 9, pp. 1820-1835.e9 . https://doi.org/10.1016/j.cmet.2021.07.008
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Gómez-valadés, A G, Pozo, M, Varela, L, Boudjadja, M B, Ramírez, S, Chivite, I, Eyre, E, Haddad-tóvolli, R, Obri, A, Milà-guasch, M, Altirriba, J, Schneeberger, M, Imbernón, M, Garcia-rendueles, A R, Gama-perez, P, Rojo-ruiz, J, Rácz, B, Alonso, M T, Gomis, R, Zorzano, A, D’agostino, G, Alvarez, C V, Nogueiras, R, Garcia-roves, P M, Horvath, T L & Claret, M 2021, ' Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis ', Cell Metabolism, vol. 33, no. 9, pp. 1820-1835.e9 . https://doi.org/10.1016/j.cmet.2021.07.008
Summary Appropriate cristae remodeling is a determinant of mitochondrial function and bioenergetics and thus represents a crucial process for cellular metabolic adaptations. Here, we show that mitochondrial cristae architecture and expression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb60a2466d25edb8839ba2edaabee22
http://hdl.handle.net/2445/180330
http://hdl.handle.net/2445/180330