Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Angela Pettinicchio"'
1
Akademický článek
Gut microbiota composition in colorectal cancer patients is genetically regulated
Autor: Francesca Colombo, Oscar Illescas, Sara Noci, Francesca Minnai, Giulia Pintarelli, Angela Pettinicchio, Alberto Vannelli, Luca Sorrentino, Luigi Battaglia, Maurizio Cosimelli, Tommaso A. Dragani, Manuela Gariboldi
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The risk of colorectal cancer (CRC) depends on environmental and genetic factors. Among environmental factors, an imbalance in the gut microbiota can increase CRC risk. Also, microbiota is influenced by host genetics. However, it is not know
Externí odkaz: https://doaj.org/article/f1e84126118f48a79e77286d07af34f2
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2
Akademický článek
Mouse pulmonary adenoma susceptibility 1 locus is an expression QTL modulating Kras-4A.
Autor: Alice Dassano, Francesca Colombo, Gaia Trincucci, Elisa Frullanti, Antonella Galvan, Angela Pettinicchio, Loris De Cecco, Andrea Borrego, Olga Célia Martinez Ibañez, Tommaso A Dragani, Giacomo Manenti
Publikováno v: PLoS Genetics, Vol 10, Iss 4, p e1004307 (2014)
Pulmonary adenoma susceptibility 1 (Pas1) is the major locus responsible for lung tumor susceptibility in mice; among the six genes mapping in this locus, Kras is considered the best candidate for Pas1 function although how it determines tumor suscep
Externí odkaz: https://doaj.org/article/94dc640eaf5c413589929d533828b21e
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3
Akademický článek
Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci.
Autor: Giacomo Manenti, Antonella Galvan, Angela Pettinicchio, Gaia Trincucci, Elena Spada, Anna Zolin, Silvano Milani, Anna Gonzalez-Neira, Tommaso A Dragani
Publikováno v: PLoS Genetics, Vol 5, Iss 1, p e1000331 (2009)
We carried out genome-wide association (GWA) studies in inbred mouse strains characterized for their lung tumor susceptibility phenotypes (spontaneous or urethane-induced) with panels of 12,959 (13K) or 138,793 (140K) single-nucleotide polymorphisms
Externí odkaz: https://doaj.org/article/e8568445cf6046c6a27ff2e8e1f08343
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4
Germline control of somatic Kras mutations in mouse lung tumors
Autor: Tommaso A. Dragani, Angela Pettinicchio, José Ricardo Jensen, Orlando Garcia Ribeiro, Andrea Borrego, Wafa Hanna Koury Cabrera, Olga M. Ibañez, Marcelo De Franco, Mara A Correa, Giacomo Manenti, Nancy Starobinas
Publikováno v: Molecular Carcinogenesis. 57:745-751
Somatic KRAS mutations are common in human lung adenocarcinomas and are associated with worse prognosis. In mice, Kras is frequently mutated in both spontaneous and experimentally induced lung tumors, although the pattern of mutation varies among str
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c61eae69671d2a0fbe3eaafa084b35
https://doi.org/10.1002/mc.22796
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5
Cigarette smoke alters the transcriptome of non-involved lung tissue in lung adenocarcinoma patients
Autor: Davide Maspero, Sara Noci, Matteo Incarbone, Loris De Cecco, Davide Tosi, Angela Pettinicchio, Luigi Santambrogio, Giulia Pintarelli, Tommaso A. Dragani, Matteo Dugo, Francesca Colombo
Publikováno v: Scientific reports (Nature Publishing Group) 9 (2019). doi:10.1038/s41598-019-49648-2
info:cnr-pdr/source/autori:Pintarelli, Giulia; Noci, Sara; Maspero, Davide; Pettinicchio, Angela; Dugo, Matteo; De Cecco, Loris; Incarbone, Matteo; Tosi, Davide; Santambrogio, Luigi; Dragani, Tommaso A.; Colombo, Francesca/titolo:Cigarette smoke alters the transcriptome of non-involved lung tissue in lung adenocarcinoma patients/doi:10.1038%2Fs41598-019-49648-2/rivista:Scientific reports (Nature Publishing Group)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Alterations in the gene expression of organs in contact with the environment may signal exposure to toxins. To identify genes in lung tissue whose expression levels are altered by cigarette smoking, we compared the transcriptomes of lung tissue betwe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a17f8245a6e225de062a20d9d0ae654
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6
Expression quantitative trait analysis reveals fine germline transcript regulation in mouse lung tumors
Autor: Angela Pettinicchio, Tommaso A. Dragani, Francesca Colombo, Loris De Cecco, Daniele Lecis, Alice Dassano, Giacomo Manenti, Matteo Dugo, Chiara E. Cotroneo
Publikováno v: Cancer letters
375 (2016): 221–230. doi:10.1016/j.canlet.2016.02.054
info:cnr-pdr/source/autori:Cotroneo, Chiara E.; Dassano, Alice; Colombo, Francesca; Pettinicchio, Angela; Lecis, Daniele; Dugo, Matteo; De Cecco, Loris; Dragani, Tommaso A.; Manenti, Giacomo/titolo:Expression quantitative trait analysis reveals fine germline transcript regulation in mouse lung tumors/doi:10.1016%2Fj.canlet.2016.02.054/rivista:Cancer letters (Print)/anno:2016/pagina_da:221/pagina_a:230/intervallo_pagine:221–230/volume:375
Gene expression modulates cellular functions in both physiologic and pathologic conditions. Herein, we carried out a genetic linkage study on the transcriptome of lung tumors induced by urethane in an (A/J x C57BL/6)F4 intercross population, whose in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa07d3a7e922f8619c1107a632ccc04
https://doi.org/10.1016/j.canlet.2016.02.054
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7
Elektronická kniha
Auditing Teams : Dynamics and Efficiency
Autor: Mara Cameran, Angelo Ditillo, Angela Pettinicchio
The recent audit failures which have rocked financial markets worldwide have accentuated the need for a better understanding of the link between risk, control and audit quality; as well as emphasising the need to open the'black box'of the ways auditi
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