Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Angela Palummo"'
Autor:
Anna Grazia Recchia, Nadia Caruso, Sabrina Bossio, Mariavaleria Pellicanò, Laura De Stefano, Stefania Franzese, Angela Palummo, Vincenzo Abbadessa, Eugenio Lucia, Massimo Gentile, Ernesto Vigna, Clementina Caracciolo, Antolino Agostino, Sara Galimberti, Luciano Levato, Fabio Stagno, Stefano Molica, Bruno Martino, Paolo Vigneri, Francesco Di Raimondo, Fortunato Morabito
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130360 (2015)
Chronic Myeloid Leukemia (CML) is characterized by a balanced translocation juxtaposing the Abelson (ABL) and breakpoint cluster region (BCR) genes. The resulting BCR-ABL1 oncogene leads to increased proliferation and survival of leukemic cells. Succ
Externí odkaz:
https://doaj.org/article/39f341d4d75e491496e8abd569aa7e72
Autor:
Rosanna Massara, Ernesto Vigna, Alessandro Gulino, Adalberto Ibatici, Martina Cardillo, Fortunato Morabito, Carlotta Massucco, Marina Fabbi, Anna Grazia Recchia, Franco Fais, Daniele Reverberi, Mariavaleria Pellicanò, Sabrina Bossio, Simona Boccardo, Silvano Ferrini, Monica Colombo, Sandra Salvi, Serena Matis, Giannamaria Cerruti, Martina Manzoni, Massimo Gentile, Antonino Neri, Laura Emionite, Sabina Sangaletti, Claudio Tripodo, Simonetta Zupo, Giovanna Cutrona, Daniela de Totero, Laura De Stefano, Sonia Fabris, Angela Palummo, Francesca Valdora, Michele Cilli, Irma Airoldi, Giovanni Iaquinta, Manlio Ferrarini
Although the progression of chronic lymphocytic leukemia (CLL) requires the cooperation of the microenvironment, the exact cellular and molecular mechanisms involved are still unclear. We investigated the interleukin (IL)-23 receptor (IL-23R)/IL-23 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652a37485c0dc625c24594451a257319
http://hdl.handle.net/10447/277163
http://hdl.handle.net/10447/277163
Autor:
Angela Palummo, Nadia Caruso, Giuseppina Uccello, Massimo Gentile, Annamaria Petrungaro, Ernesto Vigna, Fortunato Morabito, Anna Grazia Recchia, Laura De Stefano, Sabrina Bossio, Francesca Storino, Massimo Martino
Publikováno v:
Expert opinion on investigational drugs. 26(11)
Venetoclax, an orally bioavailable inhibitor of BCL-2, was approved in 2016 by the United States Food and Drug Administration (FDA) for the treatment of chronic lymphocytic leukemia (CLL) patients with 17p deletion [del(17p)], who have received at le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9972aec6643a959cab4fe88f1cf5b993
https://pubmed.ncbi.nlm.nih.gov/28972395
https://pubmed.ncbi.nlm.nih.gov/28972395
Autor:
Sabrina Bossio, Anna Grazia Recchia, Angela Palummo, Giuseppina Uccello, Massimo Gentile, Rosellina Morelli, Ernesto Vigna, Carla Mazzone, Rosa Greco, Fortunato Morabito, Caterina Musolino, Annamaria Petrungaro, Laura De Stefano
We describe the case of a patient with Philadelphia-positive acute lymphoblastic leukemia treated with dasatinib plus steroids as first-line therapy, who achieved a major molecular response (MMR) before undergoing matched, unrelated donor allogeneic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8bdbbd0ec55cefd1f4dfb0c6386820
http://hdl.handle.net/11570/3119842
http://hdl.handle.net/11570/3119842
Autor:
Laura De Stefano, Fortunato Morabito, Eugenio Lucia, Massimo Martino, Massimo Gentile, Ernesto Vigna, Anna Grazia Recchia, Carla Mazzone, Sabrina Bossio, Lucio Morabito, Teresa Granata, Angela Palummo
Publikováno v:
Expert Opinion on Pharmacotherapy. 14:2263-2280
Bendamustine is a unique bifunctional alkylating agent with promising activity in multiple myeloma (MM). It is currently licensed in Europe for use as frontline treatment with prednisolone for patients with MM who are unsuitable for transplantation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10ae301bf5a065704047c413367e73f
https://doi.org/10.1517/14656566.2013.837885
https://doi.org/10.1517/14656566.2013.837885
Autor:
Renato V. Iozzo, Jiri Jiracek, Andrea Morrione, Angela Palummo, Andrzej M. Brzozowski, Emília Kletvíková, Antonino Belfiore, Alaide Morcavallo, Marco Genua
Publikováno v:
Journal of Biological Chemistry. 287:11422-11436
The insulin receptor isoform A (IR-A) binds both insulin and insulin-like growth factor (IGF)-II, although the affinity for IGF-II is 3-10-fold lower than insulin depending on a cell and tissue context. Notably, in mouse embryonic fibroblasts lacking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b770ef2a7650b9f76cf41e0edf92a6f
https://doi.org/10.1074/jbc.m111.252478
https://doi.org/10.1074/jbc.m111.252478
Autor:
Ernesto Vigna, Sara Galimberti, Angela Palummo, Fortunato Morabito, Massimo Gentile, Clementina Caracciolo, Luciano Levato, Paolo Vigneri, Stefano Molica, Eugenio Lucia, Nadia Caruso, Anna Grazia Recchia, Bruno Martino, Vincenzo Abbadessa, Antolino Agostino, Francesco Di Raimondo, Stefania Franzese, Mariavaleria Pellicanò, Sabrina Bossio, Fabio Stagno, Laura De Stefano
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0130360 (2015)
PLoS ONE, Vol 10, Iss 6, p e0130360 (2015)
Chronic Myeloid Leukemia (CML) is characterized by a balanced translocation juxtaposing the Abelson (ABL) and breakpoint cluster region (BCR) genes. The resulting BCR-ABL1 oncogene leads to increased proliferation and survival of leukemic cells. Succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c7a0304ad8de0f0b4bc66ab4d8bc98
http://europepmc.org/articles/PMC4482505
http://europepmc.org/articles/PMC4482505
Autor:
Anna Grazia Recchia, Fortunato Morabito, Mariavaleria Pellicanò, Sabrina Bossio, Francesca Storino, Massimo Gentile, Angela Palummo, Ernesto Vigna, Nadia Caruso, Laura De Stefano, Lucio Morabito
Publikováno v:
Expert opinion on investigational drugs. 24(6)
The combination schedule of fludarabine, cyclophosphamide and rituximab is the gold standard of therapy for younger, physically fit chronic lymphocytic leukemia (CLL) patients; it allows achieving high and durable complete response rates. Although tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce9ef81218b0ae6bf7d8ea560b55695
https://pubmed.ncbi.nlm.nih.gov/25728009
https://pubmed.ncbi.nlm.nih.gov/25728009
Autor:
Annamaria Petrungaro, Nadia Caruso, Antonino Neri, Laura De Stefano, Rosa Greco, Francesca Storino, Ernesto Vigna, Anna Grazia Recchia, Angela Palummo, Fortunato Morabito, Sabrina Bossio, Giovanni Iaquinta, Massimo Gentile
Publikováno v:
Blood. 128:5204-5204
Background: Older patients (pts) with acute myeloid leukemia (AML) have a particularly dismal outcome, because of adverse features of AML in the elderly and frailty. The median duration of complete remission (CR) last less than 1 year. The optimal ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3b745c1f3a4777b9216b7a625cd3dc7
https://doi.org/10.1182/blood.v128.22.5204.5204
https://doi.org/10.1182/blood.v128.22.5204.5204
Autor:
Marco Gaspari, Alaide Morcavallo, Riccardo Vigneri, Giovanni Cuda, Giuseppe Pandini, Martin R. Larsen, Angela Palummo, Antonino Belfiore
Publikováno v:
Morcavallo, A, Gaspari, M, Pandini, G, Palummo, A, Cuda, G, Larsen, M R, Vigneri, R & Belfiore, A 2011, ' Research resource: new and diverse substrates for the insulin receptor isoform a revealed by quantitative proteomics after stimulation with igf-ii or insulin ', Molecular endocrinology (Baltimore, Md.), vol. 25, no. 8, pp. 1456-68 . https://doi.org/10.1210/me.2010-0484
The isoform A of the insulin receptor (IR) (IR-A) is a bifunctional receptor, because it binds both insulin and IGF-II. IR-A activation by IGF-II plays a role in development, but its physiological role in adults is unknown. IGF-II signaling through I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae068fe0bf9a809c5fef2d9e6a4b6995
http://hdl.handle.net/20.500.11769/318449
http://hdl.handle.net/20.500.11769/318449