Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Angela Ogden"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Centrosome amplification (CA) is a hallmark of cancer, observable in ≥75% of breast tumors. CA drives aggressive cellular phenotypes such as chromosomal instability (CIN) and invasiveness. Thus, assessment of CA may offer insights into the
Externí odkaz:
https://doaj.org/article/af3e01983a1a4d65aef64bb6f7c66452
Autor:
Angela Ogden, Ritu Aneja, Mohammed A. Aleskandarany, Uma Krishnamurti, Carlos S. Moreno, Xiaoxian Bill Li, Emiel A. M. Janssen, Padmashree C.G. Rida, Sonal Pattni, Emad A. Rakha, Kristin Jonsdottir, Ian O. Ellis, Bikram Sahoo, Nigel P. Mongan, Shristi Bhattarai, Mansour Alsaleem, Andrew R. Green
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC) biomarkers. Reduced EGFR levels can be compensated by increases in HER3; thus, assaying EGFR an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9773091fc1491adda3a2f6c8babf1bce
http://link.springer.com/article/10.1038/s41598-020-59514-1
http://link.springer.com/article/10.1038/s41598-020-59514-1
Autor:
Angela Ogden, Lauren E. McCullough, Ritu Aneja, Mylin A. Torres, Geetanjali Saini, Padmashree C.G. Rida
Publikováno v:
Cancer Causes Control
Neighborhoods encompass complex environments comprised of unique economic, physical, and social characteristics that have a profound impact on the residing individual's health and, collectively, on the community's wellbeing. Neighborhood disadvantage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04ef537b6d63282481bb50aa3ae2828
https://doi.org/10.1007/s10552-019-01180-4
https://doi.org/10.1007/s10552-019-01180-4
Autor:
Emad A. Rakha, Sara Raafat, Graham Ball, Angela Ogden, Mansour Alsaleem, Andrew R. Green, Mohammed A. Aleskandarany, Melissa Davis, Michael S. Toss, Shristi Bhattarai, Ritu Aneja, Olivier Elemento, Ian O. Ellis, Padmashree C.G. Rida, Nigel P. Mongan, Chitra Joseph, Francesca Khani
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 33(11)
The absence of a robust risk stratification tool for triple negative breast cancer (TNBC) underlies imprecise and nonselective treatment of these patients with cytotoxic chemotherapy. This study aimed to interrogate transcriptomes of TNBC resected sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016f64a1c083056d9ab5a9ca960efd29
https://pubmed.ncbi.nlm.nih.gov/32404959
https://pubmed.ncbi.nlm.nih.gov/32404959
Autor:
Michael S. Toss, Emad A. Rakha, Chitra Joseph, Padmashree C.G. Rida, Andrew R. Green, Ian O. Ellis, Nigel P. Mongan, Mohammed A. Aleskandarany, Ibrahim Alshankyty, Mansour Alsaleem, Sasagu Kurozumi, Angela Ogden, Ritu Aneja
E-cadherin is a tumor suppressor gene in invasive lobular breast cancer. However, a proportion of high-grade ductal carcinoma shows reduced/loss of E-cadherin. In this study, we assessed the underlying mechanisms and molecular implications of E-cadhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4fd096ae4d5a4d6360edf9b34a9f20
https://clok.uclan.ac.uk/34530/1/34530.pdf
https://clok.uclan.ac.uk/34530/1/34530.pdf
Publikováno v:
Pharmacology & Therapeutics. 164:120-125
Histone deacetylase 6 (HDAC6), a cytoplasmic enzyme important for many biological processes, has recently emerged as a critical regulator of viral infection. HDAC6 exerts this function either directly, via orchestrating various stages of the viral li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f3defbd77a4278d35166cc9d80c9ca
https://doi.org/10.1016/j.pharmthera.2016.04.005
https://doi.org/10.1016/j.pharmthera.2016.04.005
Autor:
Carlos Caldas, Sultan N Sonbul, Sasagu Kurozumi, Ibraheem Ashankyty, Yousif A Kariri, Leslie W Dalton, Abrar I. Aljohani, Takaaki Fujii, Andrew R. Green, Ian O. Ellis, Sami Alsaeed, Emad A. Rakha, Ken Shirabe, Sara Raafat, Chitra Joseph, Mohammed A. Aleskandarany, Simon J Johnston, Angela Ogden, Mansour Alsaleem, Nigel P. Mongan, Christine Desmedt
Publikováno v:
British Journal of Cancer
BACKGROUND: Lymphovascular invasion (LVI) is associated with the development of metastasis in invasive breast cancer (BC). However, the complex molecular mechanisms of LVI, which overlap with other oncogenic pathways, remain unclear. This study, usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b919514006551e3a3f45dcfdca8d0061
https://pubmed.ncbi.nlm.nih.gov/31114020
https://pubmed.ncbi.nlm.nih.gov/31114020
Autor:
Mylin A. Torres, Padmashree C.G. Rida, Emad A. Rakha, Angela Ogden, Brian D. Lehmann, Julie R. Palmer, Tiffany A. Traina, Ritu Aneja, Zsuzsanna Varga, Christine B. Ambrosone, Ian O. Ellis, Otis W. Brawley, Christos Hatzis, Antonio C. Wolff, Rita Nanda, Valerie Montgomery Rice
Recently, Georgia State University's Centennial Hall was the premier location for the 2017 International Conference on Triple Negative Breast Cancer (TNBC): Illuminating Actionable Biology, which was held from Sept. 18 to 20, 2017, in Atlanta, USA. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d0bd5818d68acb6f8a3a66de52c698
https://doi.org/10.5167/uzh-149647
https://doi.org/10.5167/uzh-149647
Autor:
Angela Ogden, David Pearson, Anand Pillai, Youri Peter Alexander Tan, Amanda Brooks, Jason Wong, Adam J Reid
Publikováno v:
Injury. 50:223-224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a45b958eceb68a9ef513def271efe427
https://doi.org/10.1016/j.injury.2018.11.051
https://doi.org/10.1016/j.injury.2018.11.051
Publikováno v:
Medicinal Research Reviews. 36:300-312
Microtubules, tirelessly animated and highly dynamic structures, are vital for most cellular processes and their intricacies are still being revealed even after a century since their discovery. The importance of microtubules as chemotherapeutic targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f8f1fd41f65c609d5e4fbafae0400a4
https://doi.org/10.1002/med.21378
https://doi.org/10.1002/med.21378