Zobrazeno 1 - 2
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pro vyhledávání: '"Angela Northey"'
Autor:
Kathleen M. Metters, Maria Cirino, Chi-Chung Chan, François Nantel, Robert Gordon, Angela Northey, Danielle Denis
Publikováno v:
British Journal of Pharmacology. 128:853-859
1 We characterized the regulation of cyclooxygenase-2 (COX-2) at the mRNA, protein and mediator level in two rat models of acute inflammation, carrageenan-induced paw oedema and mechanical hyperalgesia. 2 Carrageenan was injected in the hind paw of r
Publikováno v:
Prostaglandinsother lipid mediators. 62(2)
The inhibition of PGE 2 synthesis resulting from sustained NSAIDs therapy has been linked to gastrointestinal irritations and ulceration. The multiple physiological effects of PGE 2 in the gut are mediated through the activation of four receptors ter