Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Angela Matyas"'
Autor:
Samantha K. Sarkar, Angela Matyas, Ikhuosho Asikhia, Zhenkun Hu, Mia Golder, Kaitlyn Beehler, Tanja Kosenko, Thomas A. Lagace
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a secreted protein that binds and mediates endo-lysosomal degradation of low-density lipoprotein receptor (LDLR), limiting plasma clearance of cholesterol-rich LDL particles in liver. Gain-of-f
Externí odkaz:
https://doaj.org/article/5b011592ba30443bbae7dc2981011534
Autor:
Alexander C.Y. Foo, Ikhuosho Asikhia, Ariela Vergara-Jaque, Samantha K. Sarkar, Angela Matyas, Tanja Kosenko, Thomas A. Lagace, Natalie K. Goto
Publikováno v:
The Journal of Biological Chemistry
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a ligand of low-density lipoprotein (LDL) receptor (LDLR) that promotes LDLR degradation in late endosomes/lysosomes. In human plasma, 30–40% of PCSK9 is bound to LDL particles; however, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481f4569db516fc372524c2a466537e1
https://doi.org/10.1074/jbc.ra119.010221
https://doi.org/10.1074/jbc.ra119.010221
Autor:
Samantha K. Sarkar, Angela Matyas, Thomas A. Lagace, Alexander C.Y. Foo, Natalie K. Goto, Ariela Vergara-Jaque, Tanja Kosenko
SUMMARYProprotein convertase subtilisin/kexin type-9 (PCSK9) is a ligand of low-density lipoprotein receptor (LDLR) that promotes LDLR degradation in late endosomes/lysosomes. In human plasma, 30-40% of PCSK9 is bound to LDL particles; however, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9111aa7a9eb011601eeca9a40d21fa53
