Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Angela M. Tuckowski"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Caenorhabditis elegans is an instrumental model in aging research due to its large brood size, short lifespan, and malleable genetics. However, maintaining a synchronous nematode population for longevity studies is challenging and time consuming due
Externí odkaz:
https://doaj.org/article/2285e66cb797468db6b807c205e7cc59
Autor:
Hyo Sub Choi, Ajay Bhat, Marshall B. Howington, Megan L. Schaller, Rebecca L. Cox, Shijiao Huang, Safa Beydoun, Hillary A. Miller, Angela M. Tuckowski, Joy Mecano, Elizabeth S. Dean, Lindy Jensen, Daniel A. Beard, Charles R. Evans, Scott F. Leiser
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Flavin containing monooxygenase 2 (FMO-2) is known to increase lifespan under dietary restriction through incompletely understood mechanisms. Here the authors report that FMO-2 modifies tryptophan and methionine metabolic pathways to enhance stress r
Externí odkaz:
https://doaj.org/article/2e4a51166bab49ee8b478a87ad3ac370
Autor:
Hillary A. Miller, Shijiao Huang, Elizabeth S. Dean, Megan L. Schaller, Angela M. Tuckowski, Allyson S. Munneke, Safa Beydoun, Scott D. Pletcher, Scott F. Leiser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
This report finds that dietary restriction, the most extensively studied anti-aging intervention, can be mimicked by blocking food odour signaling and identifies a neural network of food perception that functions through serotonin and dopamine.
Externí odkaz:
https://doaj.org/article/3c3039c8eb084652ba7863dcb8723819
Autor:
Sarah A. Sacco, Angela M. Tuckowski, Irina Trenary, Lauren Kraft, Michael J. Betenbaugh, Jamey D. Young, Kevin D. Smith
Publikováno v:
Biotechnology and Bioengineering. 119:1712-1727
The glutamine synthetase (GS) expression system is commonly used to ensure stable transgene integration and amplification in Chinese hamster ovary (CHO) host lines. Transfected cell populations are typically grown in the presence of the GS inhibitor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65bde9b19de5462069469784864a621
https://doi.org/10.1002/bit.28084
https://doi.org/10.1002/bit.28084