Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Angela M. Pierce"'
Autor:
Alexandra Sufit, Alisa B Lee-Sherick, Deborah DeRyckere, Manali Rupji, Bhakti Dwivedi, Marileila Varella-Garcia, Angela M Pierce, Jeanne Kowalski, Xiaodong Wang, Stephen V Frye, H Shelton Earp, Amy K Keating, Douglas K Graham
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165107 (2016)
MER receptor tyrosine kinase (MERTK) is expressed in a variety of malignancies, including glioblastoma multiforme (GBM). Our previous work demonstrated that inhibition of MERTK using RNA interference induced cell death and chemosensitivity in GBM cel
Externí odkaz:
https://doaj.org/article/cc1e6a7a41364cb99820e9c9e5a6c231
Autor:
Allison P Cole, Andrew M Donson, Angela M Pierce, Enrique Grimaldo, Jacob D Calhoun, Andrea M Griesinger, Caroline Sublett, Rosandra N Kaplan, Terry J Fry, Nicholas K Foreman, Anandani Nellan
Publikováno v:
Neuro-Oncology. 24:i44-i44
Trastuzumab-based HER2 CAR-T constructs have demonstrated preclinical efficacy in medulloblastoma and are being evaluated for use in children and young adults with recurrent or refractory CNS tumors. Preliminary results demonstrate immune activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60123c0811f535f83d6b970ebc5e2fd6
https://doi.org/10.1093/neuonc/noac079.162
https://doi.org/10.1093/neuonc/noac079.162
Publikováno v:
Pathology. 33:167-171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c7b8cd26f0994917ee315aa0d45203c
https://doi.org/10.1080/00313020120038773
https://doi.org/10.1080/00313020120038773
Autor:
Sara S. Gaddis, C. Marcelo Aldaz, Angela M. Pierce, David G. Johnson, Aijin Wang, Judson-Kremer Kimberly, Michael C. MacLeod
Publikováno v:
Scopus-Elsevier
Current techniques for analysis of gene expression either monitor one gene at a time, for example northern hybridization or RT-PCR methods, or are designed for the simultaneous analysis of thousands of genes, for example microarray hybridization or s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42755763d6a1e9a406c8b4751d752794
https://doi.org/10.1093/nar/27.23.4609
https://doi.org/10.1093/nar/27.23.4609
Autor:
Angela M. Pierce, Robin Schneider-Broussard, Irma B. Gimenez-Conti, Claudio J. Conti, Jamie Russell, David G. Johnson
Publikováno v:
Molecular and Cellular Biology. 19:6408-6414
Using a transgenic mouse model expressing the E2F1 gene under the control of a keratin 5 (K5) promoter, we previously demonstrated that increased E2F1 activity can promote tumorigenesis by cooperating with either a v-Ha-ras transgene to induce benign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7448dd865e5b27902419be62446ec1
https://doi.org/10.1128/mcb.19.9.6408
https://doi.org/10.1128/mcb.19.9.6408
Publikováno v:
Molecular Carcinogenesis. 22:190-198
Several regulators of E2F transcriptional activity, including the retinoblastoma tumor suppressor (Rb) protein, p16Ink4a, cyclin D1, and cyclin-dependent kinase 4, have been shown to be targets for genetic alterations that underlie the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::341b7ffa3ff2cff878fd96efa11169f1
https://doi.org/10.1002/(sici)1098-2744(199807)22:3<190::aid-mc7>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199807)22:3<190::aid-mc7>3.0.co
Autor:
Claudio J. Conti, Luis Arboledas Martínez, Irma B. Gimenez-Conti, David G. Johnson, Robin Schneider-Broussard, Angela M. Pierce
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(15)
The p16 INK4a -cyclin D–retinoblastoma tumor suppressor pathway is disrupted in most human cancers, and it has been suggested that the subsequent release of E2F transcription factors from inhibitory complexes may be a key event in tumor development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeaedd73b9be9b4c27c57910d032e408
https://pubmed.ncbi.nlm.nih.gov/9671769
https://pubmed.ncbi.nlm.nih.gov/9671769
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development
Publikováno v:
Oncogene. 16(10)
In cell culture studies, overexpression of the E2F1 transcription factor has been shown to stimulate proliferation, induce apoptosis, and cooperate with an activated ras gene to oncogenically transform primary rodent cells. To study the effect of inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654fd7df96c929718a281df275036b17
https://pubmed.ncbi.nlm.nih.gov/9546428
https://pubmed.ncbi.nlm.nih.gov/9546428