Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Angela M. Gleason"'
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Akademický článek
Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures
Autor: Aaron D. Schwab, Amy J. Nelson, Angela M. Gleason, Oliver W. Schanze, Todd A. Wyatt, Dhananjay D. Shinde, Peng Xiao, Vinai C. Thomas, Chittibabu Guda, Kristina L. Bailey, Tammy Kielian, Geoffrey M. Thiele, Jill A. Poole
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
BackgroundEnvironmental lipopolysaccharide (LPS) and microbial component-enriched organic dusts cause significant lung disease. These environmental exposures induce the recruitment and activation of distinct lung monocyte/macrophage subpopulations in
Externí odkaz: https://doaj.org/article/086fbe7825ba451eb94481bbeca9982e
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2
Akademický článek
Validation of clinical acceptability of deep-learning-based automated segmentation of organs-at-risk for head-and-neck radiotherapy treatment planning
Autor: J. John Lucido, Todd A. DeWees, Todd R. Leavitt, Aman Anand, Chris J. Beltran, Mark D. Brooke, Justine R. Buroker, Robert L. Foote, Olivia R. Foss, Angela M. Gleason, Teresa L. Hodge, Cían O. Hughes, Ashley E. Hunzeker, Nadia N. Laack, Tamra K. Lenz, Michelle Livne, Megumi Morigami, Douglas J. Moseley, Lisa M. Undahl, Yojan Patel, Erik J. Tryggestad, Megan Z. Walker, Alexei Zverovitch, Samir H. Patel
Publikováno v: Frontiers in Oncology, Vol 13 (2023)
IntroductionOrgan-at-risk segmentation for head and neck cancer radiation therapy is a complex and time-consuming process (requiring up to 42 individual structure, and may delay start of treatment or even limit access to function-preserving care. Fea
Externí odkaz: https://doaj.org/article/b0a186e4d81f46cfb58fca481113cd77
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Myeloid Differentiation Factor 88–Dependent Signaling Is Critical for Acute Organic Dust–Induced Airway Inflammation in Mice
Autor: Todd A. Wyatt, Angela M. Gleason, Jill A. Poole, Debra J. Romberger, Tammy Kielian, Christopher Bauer, William W. West
Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 48:781-789
Organic dust exposure within agricultural environments results in airway diseases. Toll-like receptor 2 (TLR2) and TLR4 only partly account for the innate response to these complex dust exposures. To determine the central pathway in mediating complex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b201fa14b04a64795af5be98cd8e5f
https://doi.org/10.1165/rcmb.2012-0479oc
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Vitamin D Treatment Modulates Organic Dust-Induced Cellular and Airway Inflammatory Consequences
Autor: Debra J. Romberger, Todd A. Wyatt, Jill A. Poole, Angela M. Gleason, Daniel Reiff, Gregory A. Golden, Michael L. McCaskill, Christopher Bauer
Publikováno v: Journal of Biochemical and Molecular Toxicology. 27:77-86
Exposure to organic dusts elicits airway inflammatory diseases. Vitamin D recently has been associated with various airway inflammatory diseases, but its role in agricultural organic dust exposures is unknown. This study investigated whether vitamin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b8c3a7e7010d0a02d36495fa5a2ef4b
https://doi.org/10.1002/jbt.21467
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Chronic Obstructive Pulmonary Disease Patients Have Greater Systemic Responsiveness to Ex Vivo Stimulation with Swine Dust Extract and its Components Versus Healthy Volunteers
Autor: Jill A. Poole, Janel R. Harting, Debra J. Romberger, Angela M. Gleason, Susanna G. Von Essen, Neil E. Alexis, Fang Qiu
Publikováno v: Journal of Toxicology and Environmental Health, Part A. 75:1456-1470
Chronic obstructive pulmonary disease (COPD) is characterized by an airway and systemic inflammatory response. Bioaerosols/organic dusts are important agricultural pollutants that may lead to COPD. These environments are complex, containing a rich so
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2533980a2ba8dc79a19743b1ab0a637
https://doi.org/10.1080/15287394.2012.722186
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Organic dust augments nucleotide-binding oligomerization domain expression via an NF-κB pathway to negatively regulate inflammatory responses
Autor: Jeremy Stone, Angela M. Gleason, Jill A. Poole, Debra J. Romberger, Todd A. Wyatt, William W. West, Kelsey Palm, Tammy Kielian
Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 301:L296-L306
Nucleotide-binding oligomerization domain 2 (NOD2) is involved in innate immune responses to peptidoglycan degradation products. Peptidoglycans are important mediators of organic dust-induced airway diseases in exposed agriculture workers; however, t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49f716b0ec0331e2d293c8e7922d007
https://doi.org/10.1152/ajplung.00086.2011
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Pattern Recognition Scavenger Receptor A/CD204 Regulates Airway Inflammatory Homeostasis Following Organic Dust Extract Exposures
Autor: Angela M. Gleason, William W. West, Todd A. Wyatt, Debra J. Romberger, Jill A. Poole, Leigh Anderson
Exposure to agriculture organic dusts, comprised of a diversity of pathogen-associated molecular patterns, results in chronic airway diseases. The multi-functional class A macrophage scavenger receptor (SRA)/CD204 has emerged as an important class of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a52b93f40dc7edb8695b341149d257
https://europepmc.org/articles/PMC4119855/
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Organic dust, lipopolysaccharide, and peptidoglycan inhalant exposures result in bone loss/disease
Autor: Jill A. Poole, William W. West, Angela M. Gleason, Debra J. Romberger, Michael J. Duryee, Lynell Warren Klassen, Geoffrey M. Thiele, Anand Dusad, Christopher Bauer, Ted R. Mikuls
Publikováno v: American journal of respiratory cell and molecular biology. 49(5)
Skeletal health consequences associated with chronic inflammatory respiratory disease, and particularly chronic obstructive pulmonary disease (COPD), contribute to overall disease morbidity. Agricultural environmental exposures induce significant air
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe647965f4a2765c6618c3aa09977e7
https://pubmed.ncbi.nlm.nih.gov/23782057
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9
Protein kinase C epsilon is important in modulating organic-dust-induced airway inflammation
Autor: Angela M. Gleason, Todd A. Wyatt, Debra J. Romberger, William W. West, Peter J. Oldenburg, Christopher Bauer, Jill A. Poole, Joseph H. Sisson
Publikováno v: Experimental lung research. 38(8)
Organic dust samples from swine confinement facilities elicit pro-inflammatory cytokine/chemokine release from bronchial epithelial cells and monocytes, dependent, in part, upon dust-induced activation of the protein kinase C (PKC) isoform, PKCε. PK
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf000944599cfd74a3ca3d06bfc63c9
https://pubmed.ncbi.nlm.nih.gov/22897707
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αβ T cells and a mixed Th1/Th17 response are important in organic dust-induced airway disease
Autor: Neil E. Alexis, Angela M. Gleason, William W. West, Tammy Kielian, Debra J. Romberger, Stephen J. Reynolds, Christopher Bauer, Jill A. Poole
Background Organic dust exposure in agricultural environments induces an inflammatory response that attenuates over time, yet repetitive dust exposures result in chronic lung diseases. Animal models resembling this chronic lung inflammatory response
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be09709da9b18ba34d690280be82a2b
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