Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Angela M. Farrell"'
Autor:
Angela M. Farrell, Yoshikazu Uchida, M. Marek Nagiec, Ian R. Harris, Robert C. Dickson, Peter M. Elias, Walter M. Holleran
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 10, Pp 2031-2038 (1998)
The enzyme serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the first committed and rate-limiting step in sphingolipid synthesis, is up-regulated in the epidermis as part of the homeostatic repair in response to permeability barrier pe
Externí odkaz:
https://doaj.org/article/9e0311ba698e4f2190c3b08bdbd9401a
Autor:
Ian R. Harris, Angela M. Farrell, Walter M. Holleran, Simon Jackson, Carl Grunfeld, Peter M. Elias, Kenneth R. Feingold
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 2, Pp 412-422 (1998)
After permeability barrier perturbation there is an increase in the mRNA levels for key enzymes necessary for lipid synthesis in the epidermis. The mechanism(s) responsible for this regulation is unknown. Sterol regulatory element binding proteins-1a
Externí odkaz:
https://doaj.org/article/63b35a2fe85c4420bf4d2739943e9450
Autor:
Verena Pollmann, Marie-France Martin-Eauclaire, Angela M. Farrell, Hervé Darbon, Christian Legros, Olaf Pongs, Hans-Günther Knaus, Pierre E. Bougis
Publikováno v:
Journal of Biological Chemistry. 275:16918-16924
The crystal structure of the bacterial K(+) channel, KcsA (Doyle, D. A., Morais, C. J., Pfuetzner, R. A., Kuo, A., Gulbis, J. M., Cohen, S. L., Chait, B. T., and MacKinnon, R. (1998) Science 280, 69-77), and subsequent mutagenesis have revealed a hig
Publikováno v:
Microbiology. 146:1419-1427
The identification and molecular characterization of a previously unidentified lipase, gehD, from the human cutaneous commensal Staphylococcus epidermidis is reported. A lipase-GehC-deficient but otherwise isogenic mutant of S. epidermidis 9 was cons
Publikováno v:
Journal of Investigative Dermatology. 114(1):83-87
Synthesis of cholesterol, via the isoprenoid/mevalonate pathway, is required for keratinocyte growth and differentiation, and maintenance of the stratum corneum lipid lamellae. 3-hydroxy-3-methylglutaryl coenzyme A synthase catalyzes the first step i
Autor:
M. Marek Nagiec, Angela M. Farrell, Ian R. Harris, Robert C. Dickson, Walter M. Holleran, Yoshikazu Uchida, Peter M. Elias
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 10, Pp 2031-2038 (1998)
The enzyme serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the first committed and rate-limiting step in sphingolipid synthesis, is up-regulated in the epidermis as part of the homeostatic repair in response to permeability barrier pe
Autor:
Carl Grunfeld, Simon M. Jackson, Kenneth R. Feingold, Peter M. Elias, Walter M. Holleran, Angela M. Farrell, Ian Ross Harris
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 2, Pp 412-422 (1998)
After permeability barrier perturbation there is an increase in the mRNA levels for key enzymes necessary for lipid synthesis in the epidermis. The mechanism(s) responsi- ble for this regulation is unknown. Sterol regulatory element binding proteins-
Publikováno v:
Microbiology. 143:1745-1755
Five independent clones of thePropionibacterium acnesP-37 lipase gene (gehA) were obtained inEscherichia coli,and the gene was localized to a 2.75 kbXholfragment by subcloning. The five clones were shown to contain the same gene by Southern blotting
Publikováno v:
FEMS Microbiology Letters. 130:81-85
The Staphylococcus aureus 8325-4 hyaluronate lyase gene (hysA) was identified after detecting hyaluronate lyase activity expressed by phages from a genomic library. The hysA open reading frame, capable of encoding a protein of 91 980 Da, was identifi
Publikováno v:
FEMS Microbiology Letters. 130:81-85