Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Angela M. Crist"'
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Akademický článek
Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
Autor: Angela M. Crist, Kelly M. Hinkle, Xue Wang, Christina M. Moloney, Billie J. Matchett, Sydney A. Labuzan, Isabelle Frankenhauser, Nkem O. Azu, Amanda M. Liesinger, Elizabeth R. Lesser, Daniel J. Serie, Zachary S. Quicksall, Tulsi A. Patel, Troy P. Carnwath, Michael DeTure, Xiaojia Tang, Ronald C. Petersen, Ranjan Duara, Neill R. Graff-Radford, Mariet Allen, Minerva M. Carrasquillo, Hu Li, Owen A. Ross, Nilüfer Ertekin-Taner, Dennis W. Dickson, Yan W. Asmann, Rickey E. Carter, Melissa E. Murray
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Alzheimer’s disease (AD) is typically associated with hippocampal and cortical pathology, although hippocampal sparing and limbic predominant forms exist. The authors use transcriptomic analysis and neuropathology to identify genes associated with
Externí odkaz: https://doaj.org/article/4cd05f374d8e492f8281dd38dc11f183
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Vascular deficiency of Smad4 causes arteriovenous malformations: a mouse model of Hereditary Hemorrhagic Telangiectasia
Autor: Nehal R. Patel, Amanda R. Lee, Angela M. Crist, Stryder M. Meadows, Dawn E. Westhoff
Publikováno v: Angiogenesis
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder that leads to abnormal connections between arteries and veins termed arteriovenous malformations (AVM). Mutations in TGFβ pathway members ALK1, ENG and SMAD4 lead
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4e923cf58d6b13ce8a438f830200b7
https://doi.org/10.1007/s10456-018-9602-0
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Characterization of arteriovenous identity in the developing neonate mouse retina
Autor: Chandler Young, Angela M. Crist, Stryder M. Meadows
Publikováno v: Gene Expression Patterns. :22-31
The murine retina has become an ideal model to study blood vessel formation. Blood vessels in the retina undergo various processes, including remodeling and differentiation, to form a stereotypical network that consists of precisely patterned arterie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea464f3ec27c063fb08e87c13bd3302
https://doi.org/10.1016/j.gep.2017.01.002
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Annexin A3 is necessary for parallel artery-vein alignment in the mouse retina
Autor: Kelsey Carter, Stryder M. Meadows, Avery Blanks, Ondine Cleaver, Katie Huang, Nehal R. Patel, Angela M. Crist
Publikováno v: Dev Dyn
BACKGROUND: Annexin A3 (Anxa3) is a member of the calcium-regulated, cell membrane-binding family of annexin proteins. We previously confirmed that Anxa3 is expressed in the endothelial lineage in vertebrates and that loss of anxa3 in Xenopus laevis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f2da85e315b0c3e40afeb4650c2e23
https://pubmed.ncbi.nlm.nih.gov/32020697
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Angiopoietin-2 Inhibition Rescues Arteriovenous Malformation in a Smad4 Hereditary Hemorrhagic Telangiectasia Mouse Model
Autor: Janina Thoele, Xingyan Zhou, Stryder M. Meadows, Christian Klein, Amanda R. Lee, Angela M. Crist, Jovanny Zabaleta, Christoph Ullmer, Jone Garai
Background: Hereditary hemorrhagic telangiectasia is an autosomal dominant vascular disorder caused by heterozygous, loss-of-function mutations in 4 transforming growth factor beta (TGFβ) pathway members, including the central transcriptional mediat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e231fadda773c8fa359dbbec8435b00
https://europepmc.org/articles/PMC6478529/
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Aberrant Lipid Metabolism in Anaplastic Thyroid Carcinoma Reveals Stearoyl CoA Desaturase 1 as a Novel Therapeutic Target
Autor: John A. Copland, Robert C. Smallridge, James L. Miller, Han W. Tun, Laura A. Marlow, Angela M. Crist, Christina A. von Roemeling, Anthony B. Pinkerton
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 100:E697-E709
Currently there are no efficacious therapies for patients with anaplastic thyroid carcinoma (ATC) that result in long-term disease stabilization or regression.We sought to identify pathways critical for ATC cell progression and viability in an effort
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86565056b54f70619385f27ed9373a6
https://doi.org/10.1210/jc.2014-2764
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