Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans.

Autor: Kimberly F McManus, Angela M Taravella, Brenna M Henn, Carlos D Bustamante, Martin Sikora, Omar E Cornejo

Publikováno v: PLoS Genetics, Vol 13, Iss 3, p e1006560 (2017)

The human DARC (Duffy antigen receptor for chemokines) gene encodes a membrane-bound chemokine receptor crucial for the infection of red blood cells by Plasmodium vivax, a major causative agent of malaria. Of the three major allelic classes segregati

Externí odkaz: https://doaj.org/article/a8019be581f548d5ba90a9f82a765938

Ancient European dog genomes reveal continuity since the Early Neolithic

Autor: Laura R. Botigué, Shiya Song, Amelie Scheu, Shyamalika Gopalan, Amanda L. Pendleton, Matthew Oetjens, Angela M. Taravella, Timo Seregély, Andrea Zeeb-Lanz, Rose-Marie Arbogast, Dean Bobo, Kevin Daly, Martina Unterländer, Joachim Burger, Jeffrey M. Kidd, Krishna R. Veeramah

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

The European continent is thought to have played a major role in the origins of modern dogs. Here, analysing two ancient dog genomes from Germany, the authors find significant genetic continuity throughout the Neolithic period and time dog domesticat

Externí odkaz: https://doaj.org/article/37b08385a8534eb8a9250a2aa627aa7e

Comparison of village dog and wolf genomes highlights the role of the neural crest in dog domestication

Autor: Krishna R. Veeramah, Feichen Shen, Adam R. Boyko, Angela M. Taravella, Jeffrey M. Kidd, S. Emery, Amanda L. Pendleton

Publikováno v: BMC Biology, Vol 16, Iss 1, Pp 1-21 (2018)
BMC Biology

Background Domesticated from gray wolves between 10 and 40 kya in Eurasia, dogs display a vast array of phenotypes that differ from their ancestors, yet mirror other domesticated animal species, a phenomenon known as the domestication syndrome. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c49818ff5f3b562ab52288aa95473d1
http://link.springer.com/article/10.1186/s12915-018-0535-2

137 ancient human genomes from across the Eurasian steppes

Autor: Karl-Göran Sjögren, Nina Lau, Nikolay N. Kradin, Igor Kukushkin, Arman Beisenov, Kadicha Tashbaeva, Andrey Logvin, Peter de Barros Damgaard, Irina Shevnina, Viktor K. Mertz, Ilya V. Mertz, Alexander Tkachev, Amy Goldberg, Zaruhi Khachatryan, Vyacheslav Moiyesev, Nina Marchi, Valeriy Evdokimov, Gabit Baimbetov, Valeriy Loman, Turaly Tulegenov, Evgeniy Dmitriev, Kasper Nielsen, Diimaajav Erdenebaatar, Lotte Hedeager, Levon Yepiskoposyan, Almaz Aldashev, Egor Kitov, Evelyne Heyer, Kristian Kristiansen, Victor Varfolomeev, Nurbol Baimukhanov, Enkhbayar Mijiddorj, Tereza Štolcová, Melissa A. Wilson Sayres, Sturla Ellingvåg, Dmitriy Voyakin, Gennady Afanasiev, Simon Rasmussen, Anders Gorm Pedersen, Ashyk Alpaslan, Mikkel Winther Pedersen, Ashot Margaryan, Sainbileg Undrakhbold, Z. Orozbekova, Bekmukhanbet Nurmukhanbetov, Tabaldiev Kubatbek, Eske Willerslev, Andrey Gromov, Ruslan Khaskhanov, Hakon Hakonarson, Alina Kolbina, Václav Smrčka, Rasmus Nielsen, Morten E. Allentoft, Gulmira Mukhtarova, Martin Sikora, Gabriel Renaud, J. Víctor Moreno-Mayar, Bazartseren Boldgiv, Angela M. Taravella, Tatyana Hegay, Choduraa Dorzhu, Emma Usmanova, Karol Pieta, Inga Merkyte, Alexey Kukushkin, Michaël Peyrot, Kunbolot Akmatov, Karin Margarita Frei, Vladimir I. Bazaliiskii, Thorfinn Sand Korneliussen, Alexander Goryachev, Ludovic Orlando, Andrzej W. Weber, Irina P. Panyushkina, Rana Dajani, Bazartseren Boldbaatar

Publikováno v: Nature
Nature, Nature Publishing Group, 2018, 557 (7705), pp.369-374. ⟨10.1038/s41586-018-0094-2⟩
Damgaard, P D B, Marchi, N, Rasmussen, S, Frei, K M & Willerslev, E 2018, ' 137 ancient human genomes from across the Eurasian steppes ', Nature, vol. 557, pp. 369-374 . https://doi.org/10.1038/s41586-018-0094-2
Nature, 557, 369-374

For thousands of years the Eurasian steppes have been a centre of human migrations and cultural change. Here we sequence the genomes of 137 ancient humans (about 1× average coverage), covering a period of 4,000 years, to understand the population hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb3417d5c765686402cd4900f134874
https://hal.archives-ouvertes.fr/hal-02277549

Comparison of village dog and wolf genomes highlights the pivotal role of the neural crest in dog domestication

Autor: Adam R. Boyko, Krishna R. Veeramah, Feichen Shen, Jeffrey M. Kidd, S. Emery, Angela M. Taravella, Amanda L. Pendleton

BackgroundDogs (Canis lupus familiaris) were domesticated from gray wolves between 10-40 kya in Eurasia, yet details surrounding the process of domestication remain unclear. The vast array of phenotypes exhibited by dogs mirror other domesticated ani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0769cd1cbbf9d60490075c85bae7cf
https://doi.org/10.1101/118794