The role of Neanderthal introgression in liver cancer

Autor: Angela M. Taravella Oill, Kenneth H. Buetow, Melissa A. Wilson

Publikováno v: BMC Medical Genomics, Vol 15, Iss 1, Pp 1-15 (2022)

Abstract Background Neanderthal introgressed DNA has been linked to different normal and disease traits including immunity and metabolism—two important functions that are altered in liver cancer. However, there is limited understanding of the relat

Externí odkaz: https://doaj.org/article/a6681f0f943c41d9aff9d6d0be85f15a

Ancient European dog genomes reveal continuity since the Early Neolithic

Autor: Laura R. Botigué, Shiya Song, Amelie Scheu, Shyamalika Gopalan, Amanda L. Pendleton, Matthew Oetjens, Angela M. Taravella, Timo Seregély, Andrea Zeeb-Lanz, Rose-Marie Arbogast, Dean Bobo, Kevin Daly, Martina Unterländer, Joachim Burger, Jeffrey M. Kidd, Krishna R. Veeramah

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

The European continent is thought to have played a major role in the origins of modern dogs. Here, analysing two ancient dog genomes from Germany, the authors find significant genetic continuity throughout the Neolithic period and time dog domesticat

Externí odkaz: https://doaj.org/article/37b08385a8534eb8a9250a2aa627aa7e

Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans.

Autor: Kimberly F McManus, Angela M Taravella, Brenna M Henn, Carlos D Bustamante, Martin Sikora, Omar E Cornejo

Publikováno v: PLoS Genetics, Vol 13, Iss 3, p e1006560 (2017)

The human DARC (Duffy antigen receptor for chemokines) gene encodes a membrane-bound chemokine receptor crucial for the infection of red blood cells by Plasmodium vivax, a major causative agent of malaria. Of the three major allelic classes segregati

Externí odkaz: https://doaj.org/article/a8019be581f548d5ba90a9f82a765938

PopInf: An approach for reproducibly visualizing and assigning population affiliation in genomic samples of uncertain origin

Autor: Melissa A. Wilson, Heini M. Natri, Anagha J. Deshpande, Angela M. Taravella Oill

Publikováno v: J Comput Biol

Germline genetic variation contributes to cancer etiology, but self-reported race is not always consistent with genetic ancestry, and samples may not have identifying ancestry information. Here we describe a flexible computational pipeline, PopInf, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1beda54dd866fb111340d9047f335081
https://doi.org/10.1101/823344

Author Correction: 137 ancient human genomes from across the Eurasian steppes

Autor: Karin Margarita Frei, Vyacheslav Moiyesev, Vladimir I. Bazaliiskii, Thorfinn Sand Korneliussen, Ashyk Alpaslan, Alexander Goryachev, Ruslan Khaskhanov, Andrey Gromov, Nikolay N. Kradin, Amy Goldberg, Bazartseren Boldgiv, Melissa A. Wilson Sayres, Emma Usmanova, Dmitriy Voyakin, Enkhbayar Mijiddorj, Kunbolot Akmatov, Alina Kolbina, Kadicha Tashbaeva, Tereza Štolcová, Zaruhi Khachatryan, Bazartseren Boldbaatar, Karol Pieta, Anders Gorm Pedersen, Nina Lau, Egor Kitov, Levon Yepiskoposyan, Karl-Göran Sjögren, Alexander Tkachev, Simon Rasmussen, Sturla Ellingvåg, Z. Orozbekova, Andrzej W. Weber, Tatyana Hegay, Martin Sikora, Choduraa Dorzhu, Nina Marchi, Valeriy Evdokimov, Gabriel Renaud, Peter de Barros Damgaard, Diimaajav Erdenebaatar, Irina P. Panyushkina, Sainbileg Undrakhbold, Morten E. Allentoft, Gabit Baimbetov, Eske Willerslev, J. Víctor Moreno-Mayar, Viktor K. Mertz, Evgeniy Dmitriev, Ashot Margaryan, Hakon Hakonarson, Bekmukhanbet Nurmukhanbetov, Inga Merkyte, Gulmira Mukhtarova, Irina Shevnina, Kasper Nielsen, Victor Varfolomeev, Nurbol Baimukhanov, Gennady Afanasiev, Arman Beisenov, Evelyne Heyer, Ludovic Orlando, Rasmus Nielsen, Angela M. Taravella, Tabaldiev Kubatbek, Valeriy Loman, Turaly Tulegenov, Václav Smrčka, Lotte Hedeager, Alexey Kukushkin, Michaël Peyrot, Almaz Aldashev, Kristian Kristiansen, Mikkel Winther Pedersen, Rana Dajani, Igor Kukushkin, Andrey Logvin, Ilya V. Mertz

Publikováno v: De Barros Damgaard, P, Marchi, N, Rasmussen, S, Peyrot, M, Renaud, G, Korneliussen, T, Moreno-Mayar, J V, Pedersen, M W, Goldberg, A, Usmanova, E, Baimukhanov, N, Loman, V, Hedeager, L, Pedersen, A G, Nielsen, K, Afanasiev, G, Akmatov, K, Aldashev, A, Alpaslan, A, Baimbetov, G, Bazaliiskii, V I, Beisenov, A, Boldbaatar, B, Boldgiv, B, Dorzhu, C, Ellingvag, S, Erdenebaatar, D, Dajani, R, Dmitriev, E, Evdokimov, V, Frei, K M, Gromov, A, Goryachev, A, Hakonarson, H, Hegay, T, Khachatryan, Z, Khaskhanov, R, Kitov, E, Kolbina, A, Kubatbek, T, Kukushkin, A, Kukushkin, I, Lau, N, Margaryan, A, Merkyte, I, Mertz, I V, Mertz, V K, Mijiddorj, E, Moiyesev, V, Mukhtarova, G, Nurmukhanbetov, B, Orozbekova, Z, Panyushkina, I, Pieta, K, Smrčka, V, Shevnina, I, Logvin, A, Sjögren, K G, Štolcová, T, Taravella, A M, Tashbaeva, K, Tkachev, A, Tulegenov, T, Voyakin, D, Yepiskoposyan, L, Undrakhbold, S, Varfolomeev, V, Weber, A, Sayres, M A W, Kradin, N, Allentoft, M E, Orlando, L, Nielsen, R, Sikora, M, Heyer, E, Kristiansen, K & Willerslev, E 2018, ' Author Correction: 137 ancient human genomes from across the Eurasian steppes ', Nature, vol. 557 . https://doi.org/10.1038/s41586-018-0488-1

In this Article, Angela M. Taravella and Melissa A. Wilson Sayres have been added to the author list (associated with: School of Life Sciences, Center for Evolution and Medicine, The Biodesign Institute, Arizona State University, Tempe, AZ, USA). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9de93a404a1ef1a8c544fea24767d8d
https://doi.org/10.1038/s41586-018-0488-1