Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Angela M Mitchell"'
Autor:
Ashutosh K Rai, Katsuhiro Sawasato, Haley C Bennett, Anastasiia Kozlova, Genevieve C Sparagna, Mikhail Bogdanov, Angela M Mitchell
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011335 (2024)
The outer membrane of gram-negative bacteria is a barrier to chemical and physical stress. Phospholipid transport between the inner and outer membranes has been an area of intense investigation and, in E. coli K-12, it has recently been shown to be m
Externí odkaz:
https://doaj.org/article/f094dc55d44c4f668d60480e3006a7e3
Publikováno v:
eLife, Vol 5 (2016)
Lipoprotein RcsF is the OM component of the Rcs envelope stress response. RcsF exists in complexes with β-barrel proteins (OMPs) allowing it to adopt a transmembrane orientation with a lipidated N-terminal domain on the cell surface and a periplasmi
Externí odkaz:
https://doaj.org/article/834ce531e7524653baca43f47d050b4b
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT The Gram-negative cell envelope is a complex structure delineating the cell from its environment. Recently, we found that enterobacterial common antigen (ECA) plays a role maintaining the outer membrane (OM) permeability barrier, which exclu
Externí odkaz:
https://doaj.org/article/d3ff950bec1642f5a3b588f7bb6b94bc
Autor:
Ashutosh K. Rai, Angela M. Mitchell
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT The outer membrane (OM) of Gram-negative bacteria poses a barrier to antibiotic entry due to its high impermeability. Thus, there is an urgent need to study the function and biogenesis of the OM. In Enterobacterales, an order of bacteria wit
Externí odkaz:
https://doaj.org/article/4401524eec57486abdb363f1d348479a
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Gram-negative bacteria produce lipid-anchored lipoproteins that are trafficked to their outer membrane (OM). These lipoproteins are essential components in each of the molecular machines that build the OM, including the Bam machine that asse
Externí odkaz:
https://doaj.org/article/7cbc509f760b4c7ea83e858cf69fcb8c
Autor:
Kinsey N. Morris, Angela M. Mitchell
Publikováno v:
Journal of Bacteriology. 205
The gram-negative outer membrane (OM) is an asymmetric bilayer with phospholipids in its inner leaflet and mainly lipopolysaccharide (LPS) in its outer leaflet and is largely impermeable to many antibiotics. InEnterobacterales(e.g.,Escherichia, Salmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be8c6611a63c588e639b8c9b8c3558f
https://doi.org/10.1128/jb.00403-22
https://doi.org/10.1128/jb.00403-22
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Gram-negative bacteria have an outer membrane (OM) impermeable to many toxic compounds that can be further strengthened during stress. In Enterobacteriaceae, the envelope contains enterobacterial common antigen (ECA), a carbohydrate-derived
Externí odkaz:
https://doaj.org/article/01a1c4071d6746baba160c568f8e5273
Autor:
Angela M. Mitchell, Erin E. Baschal, Kristen A. McDaniel, Kimber M. Simmons, Laura Pyle, Kathleen Waugh, Andrea K. Steck, Liping Yu, Peter A. Gottlieb, Marian J. Rewers, Maki Nakayama, Aaron W. Michels
Publikováno v:
JCI Insight. 7
T cell receptor (TCR) sequences are exceptionally diverse and can now be comprehensively measured with next-generation sequencing technologies. However, a thorough investigation of longitudinal TCR repertoires throughout childhood in health and durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54bcbb5a43dd57d0f113a54037dc942
https://doi.org/10.1172/jci.insight.161885
https://doi.org/10.1172/jci.insight.161885
Autor:
ANGELA M. MITCHELL, ERIN E. BASCHAL, KRISTEN MCDANIEL, LAURA PYLE, KATHLEEN WAUGH, ANDREA STECK, LIPING YU, PETER GOTTLIEB, MARIAN REWERS, MAKI NAKAYAMA, AARON W. MICHELS
Publikováno v:
Diabetes. 71
In type 1 diabetes (T1D) , T cells target and destroy pancreatic beta cells. T cells express T cell receptors (TCRs) which recognize peptide antigens, and each TCR is unique to a given T cell. To understand the TCR repertoire during T1D development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc37d7676dd554cd6ddb34979404c79
https://doi.org/10.2337/db22-185-or
https://doi.org/10.2337/db22-185-or
Autor:
Taylor K. Armstrong, Kimber M. Simmons, Angela M. Mitchell, Aimon A. Alkanani, Erin E. Baschal, Kristen A. McDaniel, Liping Yu, Aaron W. Michels, Laura Pyle
Publikováno v:
Diabetes. 69:1763-1769
Certain HLA class II genes increase the risk for type 1 diabetes (T1D) development while others provide protection from disease development. HLA class II alleles encode MHC proteins on antigen-presenting cells, which function to present peptides and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b59ac7340c68898072616b4857f85de
https://doi.org/10.2337/db20-0038
https://doi.org/10.2337/db20-0038