Zobrazeno 1 - 10
of 521
pro vyhledávání: '"Angela M Christiano"'
Autor:
Karl Gledhill, Zongyou Guo, Noriko Umegaki-Arao, Claire A Higgins, Munenari Itoh, Angela M Christiano
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136713 (2015)
The current utility of 3D skin equivalents is limited by the fact that existing models fail to recapitulate the cellular complexity of human skin. They often contain few cell types and no appendages, in part because many cells found in the skin are d
Externí odkaz:
https://doaj.org/article/016db432d57c4c72ba43a986c26c005f
Autor:
Alison G Barber, Mireia Castillo-Martin, Dennis M Bonal, Benjamin A Rybicki, Angela M Christiano, Carlos Cordon-Cardo
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98786 (2014)
The expression of desmogleins (DSGs), which are known to be crucial for establishing and maintaining the cell-cell adhesion required for tissue integrity, has been well characterized in the epidermis and hair follicle; however, their expression in ot
Externí odkaz:
https://doaj.org/article/4a576e25a0a34496b440d69d31576dbc
Autor:
Gina M DeStefano, Mazen Kurban, Kwame Anyane-Yeboa, Claudia Dall'Armi, Gilbert Di Paolo, Heather Feenstra, Nanette Silverberg, Luis Rohena, Larissa D López-Cepeda, Vaidehi Jobanputra, Katherine A Fantauzzo, Maija Kiuru, Marija Tadin-Strapps, Antonio Sobrino, Anna Vitebsky, Dorothy Warburton, Brynn Levy, Julio C Salas-Alanis, Angela M Christiano
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004333 (2014)
Inherited hypertrichoses are rare syndromes characterized by excessive hair growth that does not result from androgen stimulation, and are often associated with additional congenital abnormalities. In this study, we investigated the genetic defect in
Externí odkaz:
https://doaj.org/article/65db4364744e4cf1ad68da21aaf3ce4d
Autor:
Munenari Itoh, Noriko Umegaki-Arao, Zongyou Guo, Liang Liu, Claire A Higgins, Angela M Christiano
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77673 (2013)
Recent generation of patient-specific induced pluripotent stem cells (PS-iPSCs) provides significant advantages for cell- and gene-based therapy. Establishment of iPSC-based therapy for skin diseases requires efficient methodology for differentiating
Externí odkaz:
https://doaj.org/article/b658b103254a4087ace20e188c768ae4
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003002 (2012)
Hereditary hypertrichoses are a group of hair overgrowth syndromes that are extremely rare in humans. We have previously demonstrated that a position effect on TRPS1 is associated with hypertrichosis in humans and mice. To gain insight into the funct
Externí odkaz:
https://doaj.org/article/5596d0cf95a649b589ee654e85959201
Autor:
Hyunmi Kim, Alexandre Casta, Xiuwei Tang, Courtney T Luke, Arianna L Kim, David R Bickers, Mohammad Athar, Angela M Christiano
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39691 (2012)
In order to model squamous cell carcinoma development in vivo, researchers have long preferred hairless mouse models such as SKH-1 mice that have traditionally been classified as 'wild-type' mice irrespective of the genetic factors underlying their h
Externí odkaz:
https://doaj.org/article/5b57d14eff4344a795633e0ac58868fc
Autor:
Yask Gupta, Anna Lara Ernst, Artem Vorobyev, Foteini Beltsiou, Detlef Zillikens, Katja Bieber, Simone Sanna-Cherchi, Angela M. Christiano, Christian D. Sadik, Ralf J. Ludwig, Tanya Sezin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
In this study, 591 mice from an advanced-intercross mouse line were used to provide evidence that fungi are regulated by host genetics, while uncovering a regulatory role of diet on the composition of fungi in the murine gut.
Externí odkaz:
https://doaj.org/article/f9d4b29bc4eb41828406e434b6057330
Autor:
George I. Austin, Heekuk Park, Yoli Meydan, Dwayne Seeram, Tanya Sezin, Yue Clare Lou, Brian A. Firek, Michael J. Morowitz, Jillian F. Banfield, Angela M. Christiano, Itsik Pe’er, Anne-Catrin Uhlemann, Liat Shenhav, Tal Korem
Publikováno v:
Nature Biotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f9a351508e32d073aee60b75242f44
https://doi.org/10.1038/s41587-023-01696-w
https://doi.org/10.1038/s41587-023-01696-w
Publikováno v:
Journal of Investigative Dermatology. 143:527-528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95626658cb30cf61adf247c7a8a93a23
https://doi.org/10.1016/j.jid.2023.01.004
https://doi.org/10.1016/j.jid.2023.01.004
Autor:
Zhenpeng, Dai, Tanya, Sezin, Yuqian, Chang, Eunice Y, Lee, Eddy Hsi Chun, Wang, Angela M, Christiano
Publikováno v:
Frontiers in Immunology. 13
Alopecia areata (AA) is an autoimmune disease caused by T cell-mediated destruction of the hair follicle (HF). Therefore, approaches that effectively disrupt pathogenic T cell responses are predicted to have therapeutic benefit for AA treatment. T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856095e1168f054abe5cfb6c964593fd
https://doi.org/10.3389/fimmu.2022.955038
https://doi.org/10.3389/fimmu.2022.955038