Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Angela Leo"'
Combination immunotherapy using G-CSF and oncolytic virotherapy reduces tumor growth in osteosarcoma
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Osteosarcoma is the most common malignant solid tumor that affects bones, however, survival rates of patients with relapsed osteosarcoma have not improved in the last 30 years. Oncolytic virotherapy, which uses viruses designed to selectiv
Externí odkaz:
https://doaj.org/article/3b8f004cf8c74124b047b48a25e72609
Autor:
Laura Pietrovito, Angela Leo, Valentina Gori, Matteo Lulli, Matteo Parri, Valentina Becherucci, Luisa Piccini, Franco Bambi, Maria Letizia Taddei, Paola Chiarugi
Publikováno v:
Molecular Oncology, Vol 12, Iss 5, Pp 659-676 (2018)
There is growing evidence to suggest that bone marrow‐derived mesenchymal stem cells (BM‐MSCs) are key players in tumour stroma. Here, we investigated the cross‐talk between BM‐MSCs and osteosarcoma (OS) cells. We revealed a strong tropism of
Externí odkaz:
https://doaj.org/article/b700f289a2f24f0f80303249a1238d2e
Autor:
Helmut Klocker, Gabri Van der Pluijm, Zoran Culig, Iris Eder, Isabel Heidegger, Angela Leo, Jan Kroon, Georg Schaefer, Florian Handle, Christian Ploner, Andrea Eigentler, Julia Hoefer, Martin Puhr
(A) Western blot analysis of GR and AR protein expression in different passages of long-term vehicle-ctrl treated LNCaPabl cells before and during (>10 mo) cultivation in the presence of EtOH.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793fe0622186bcdaa73edfec1078efc6
https://doi.org/10.1158/1078-0432.22465323.v1
https://doi.org/10.1158/1078-0432.22465323.v1
Autor:
Helmut Klocker, Gabri Van der Pluijm, Zoran Culig, Iris Eder, Isabel Heidegger, Angela Leo, Jan Kroon, Georg Schaefer, Florian Handle, Christian Ploner, Andrea Eigentler, Julia Hoefer, Martin Puhr
Suppl Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f392cfa31457bf94efa0a33b22e18cf
https://doi.org/10.1158/1078-0432.22465320
https://doi.org/10.1158/1078-0432.22465320
Autor:
Helmut Klocker, Gabri Van der Pluijm, Zoran Culig, Iris Eder, Isabel Heidegger, Angela Leo, Jan Kroon, Georg Schaefer, Florian Handle, Christian Ploner, Andrea Eigentler, Julia Hoefer, Martin Puhr
Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504c81cc643d9503c94d177934153c46
https://doi.org/10.1158/1078-0432.22465317.v1
https://doi.org/10.1158/1078-0432.22465317.v1
Autor:
Helmut Klocker, Gabri Van der Pluijm, Zoran Culig, Iris Eder, Isabel Heidegger, Angela Leo, Jan Kroon, Georg Schaefer, Florian Handle, Christian Ploner, Andrea Eigentler, Julia Hoefer, Martin Puhr
Purpose: The major obstacle in the management of advanced prostate cancer is the occurrence of resistance to endocrine therapy. Although the androgen receptor (AR) has been linked to therapy failure, the underlying escape mechanisms have not been ful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d754fc3d5aff54c0e32a43132d439d9
https://doi.org/10.1158/1078-0432.c.6525993
https://doi.org/10.1158/1078-0432.c.6525993
Publikováno v:
Cells, Vol 9, Iss 2, p 510 (2020)
Sarcomas are rare and heterogeneous malignant tumors relatively resistant to radio- and chemotherapy. Sarcoma progression is deeply dependent on environmental conditions that sustain both cancer growth and invasive abilities. Sarcoma microenvironment
Externí odkaz:
https://doaj.org/article/2335aaaf74de4e01bc9e93a29fd69c64
Autor:
Amelia McCartney, Chiara Biagioni, Bingshu Chen, Lois Shepherd, Karen Gelmon, Anil A. Joy, Wendy Parulekar, Mattias Bergqvist, Ilenia Migliaccio, Angela Leo, Matteo Benelli, Emanuela Risi, Erica Moretti, Luca Livraghi, Laura Biganzoli, Luca Malorni
Publikováno v:
Cancer Research. 83:P5-02
Background: Thymidine kinase-1 is a cell proliferation marker downstream of the CDK4/6 pathway, whose activity can be measured in serum to reflect tumor proliferation. The CDK4/6 inhibitor palbociclib (P) is approved for the treatment of patients (pt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f220a516207ca63765f0c926ea85bcd7
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-27
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-27
Autor:
Luca Malorni, Matteo Benelli, Yuan Liu, Shibing Deng, Zhe Zhang, Cristina Guarducci, Angela Leo, Agostina Nardone, Francesca Galardi, Emanuela Risi, Erica Moretti, Dario Romagnoli, Chiara Biagioni, Marta Paoli, Laura Biganzoli, Ilenia Migliaccio
Publikováno v:
Cancer Research. 83:P5-02
Background: We have previously identified two potentially predictive signatures of palbociclib resistance: the RBsig, composed of E2F1/E2F2 dependent genes, which is correlated with genetic loss of RB1, and the ratio between the gene expression level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d5f36eebee580a9b46b7cda4cb962fb
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-17
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-17
Autor:
Grant Hogg, Qian Zeng, Heidi M Hoffman, Eric A. Severson, Li Cai, Wenjie Chen, Sabrina Gardner, Kimberly A Holden, Lax Iyer, Angela Leo Kenyon, Deborah Boles, Scott Parker, Stanley Letovsky, Henry Dong, Narasimhan Nagan, Shakti Ramkissoon, Marcia Eisenberg, Anjen Chenn, Taylor J Jensen
Publikováno v:
Blood. 140:9783
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6841073458f4c60344e817493ad5edb
https://doi.org/10.1182/blood-2022-160424
https://doi.org/10.1182/blood-2022-160424