Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Angela L. Linderholm"'
Autor:
Ayodeji Adegunsoye, Chad A. Newton, Justin M. Oldham, Brett Ley, Cathryn T. Lee, Angela L. Linderholm, Jonathan H. Chung, Nicole Garcia, Da Zhang, Rekha Vij, Robert Guzy, Renea Jablonski, Remzi Bag, Rebecca S. Voogt, Shwu-Fan Ma, Anne I. Sperling, Ganesh Raghu, Fernando J. Martinez, Mary E. Strek, Paul J. Wolters, Christine Kim Garcia, Brandon L. Pierce, Imre Noth
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The association of telomere length with age and mortality across racially diverse pulmonary fibrosis populations is unknown. Here, the authors show that leukocyte telomere length associates with chronologic age and is predictive of mortality in pulmo
Externí odkaz:
https://doaj.org/article/0bc191d2efb44548bed2e6c7dc646b0c
Publikováno v:
ERJ Open Research, Vol 5, Iss 1 (2019)
Background Bronchial thermoplasty is a nonpharmacological, device-based treatment option for a specific population of severe asthmatic subjects, but the underlying mechanisms are largely unknown. The purpose of this study is to identify potential alt
Externí odkaz:
https://doaj.org/article/a0b29642a5dc4fe486bb3b10d0671c0f
Autor:
Justin M. Oldham, Richard J Allen, Jose M. Lorenzo-Salazar, Philip L Molyneaux, Shwu-Fan Ma, Chitra Joseph, John S. Kim, Beatriz Guillen-Guio, Tamara Hernández-Beeftink, Jonathan A Kropski, Yong Huang, Cathryn T. Lee, Ayodeji Adegunsoye, Janelle Vu Pugashetti, Angela L Linderholm, Vivian Vo, Mary E. Strek, Jonathan Jou, Adrian Muñoz-Barrera, Luis A. Rubio-Rodriguez, Richard Hubbard, Nik Hirani, Moira K. B. Whyte, Simon Hart, Andrew G Nicholson, Lisa Lancaster, Helen Parfrey, Doris Rassl, William Wallace, Eleanor Valenzi, Yingze Zhang, Josyf Mychaleckyj, Amy Stockwell, Naftali Kaminski, Paul J Wolters, Maria Molina-Molina, Nicholas E Banovich, William A Fahy, Fernando J. Martinez, Ian P. Hall, Martin D Tobin, Toby M. Maher, Timothy S Blackwell, Brian L Yaspan, R Gisli Jenkins, Carlos Flores, Louise V Wain, Imre Noth
RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by limited treatment options and high mortality. A better understanding of the molecular drivers of IPF progression is needed. OBJECTIVE: To identify and validate m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0e3cc75b707b757226ca9a6d4c4575
http://hdl.handle.net/10044/1/102163
http://hdl.handle.net/10044/1/102163
Autor:
Anna L. Peljto, Rachel Z. Blumhagen, Avram D. Walts, Jonathan Cardwell, Julia Powers, Tamera J. Corte, Joanne L. Dickinson, Ian Glaspole, Yuben P. Moodley, Martina Koziar Vasakova, Elisabeth Bendstrup, Jesper R. Davidsen, Raphael Borie, Bruno Crestani, Philippe Dieude, Francesco Bonella, Ulrich Costabel, Gunnar Gudmundsson, Seamas C. Donnelly, Jim Egan, Michael T. Henry, Michael P. Keane, Marcus P. Kennedy, Cormac McCarthy, Aoife N. McElroy, Joshua A. Olaniyi, Katherine M. A. O’Reilly, Luca Richeldi, Paolo M. Leone, Venerino Poletti, Francesco Puppo, Sara Tomassetti, Valentina Luzzi, Nurdan Kokturk, Nesrin Mogulkoc, Christine A. Fiddler, Nikhil Hirani, R. Gisli Jenkins, Toby M. Maher, Philip L. Molyneaux, Helen Parfrey, Rebecca Braybrooke, Timothy S. Blackwell, Peter D. Jackson, Steven D. Nathan, Mary K. Porteous, Kevin K. Brown, Jason D. Christie, Harold R. Collard, Oliver Eickelberg, Elena E. Foster, Kevin F. Gibson, Marilyn Glassberg, Daniel J. Kass, Jonathan A. Kropski, David Lederer, Angela L. Linderholm, Jim Loyd, Susan K. Mathai, Sydney B. Montesi, Imre Noth, Justin M. Oldham, Amy J. Palmisciano, Cristina A. Reichner, Mauricio Rojas, Jesse Roman, Neil Schluger, Barry S. Shea, Jeffrey J. Swigris, Paul J. Wolters, Yingze Zhang, Cecilia M. A. Prele, Juan I. Enghelmayer, Maria Otaola, Christopher J. Ryerson, Mauricio Salinas, Martina Sterclova, Tewodros H. Gebremariam, Marjukka Myllärniemi, Roberto G. Carbone, Haruhiko Furusawa, Masaki Hirose, Yoshikazu Inoue, Yasunari Miyazaki, Ken Ohta, Shin Ohta, Tsukasa Okamoto, Dong Soon Kim, Annie Pardo, Moises Selman, Alvaro U. Aranda, Moo Suk Park, Jong Sun Park, Jin Woo Song, Maria Molina-Molina, Lurdes Planas-Cerezales, Gunilla Westergren-Thorsson, Albert V. Smith, Ani W. Manichaikul, John S. Kim, Stephen S. Rich, Elizabeth C. Oelsner, R. Graham Barr, Jerome I. Rotter, Josee Dupuis, George O’Connor, Ramachandran S. Vasan, Michael H. Cho, Edwin K. Silverman, Marvin I. Schwarz, Mark P. Steele, Joyce S. Lee, Ivana V. Yang, Tasha E. Fingerlin, David A. Schwartz
Rationale: Idiopathic pulmonary fibrosis is a rare, irreversible, and progressive disease of the lungs. Common genetic variants, in addition to non-genetic factors, have been consistently associated with IPF. Rare variants identified by candidate gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0670c24aedc8efa23979477ed15d39b
http://hdl.handle.net/10044/1/101620
http://hdl.handle.net/10044/1/101620
Autor:
Angela L. Linderholm, Laura A. Cagle, Lisa M. Franzi, Beate Illek, Richart W Harper, Sabrina N. Hoehne, Nicholas J. Kenyon
Publikováno v:
Am J Respir Cell Mol Biol
Positive-pressure ventilation results in ventilator-induced lung injury, and few therapeutic modalities have been successful at limiting the degree of injury to the lungs. Understanding the primary drivers of ventilator-induced lung injury will aid i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd040da3be516b83f482de311033e01f
https://doi.org/10.1165/rcmb.2020-0197oc
https://doi.org/10.1165/rcmb.2020-0197oc
Autor:
Justin M. Oldham, Richard J. Allen, Jose M. Lorenzo-Salazar, Philip L. Molyneaux, Shwu-Fan Ma, Chitra Joseph, John S. Kim, Beatriz Guillen-Guio, Tamara Hernández-Beeftink, Jonathan A. Kropski, Yong Huang, Cathryn T. Lee, Ayodeji Adegunsoye, Janelle Vu Pugashetti, Angela L. Linderholm, Vivian Vo, Mary E. Strek, Jonathan Jou, Adrian Muñoz-Barrera, Luis A. Rubio-Rodriguez, Richard Hubbard, Nik Hirani, Moira K.B. Whyte, Simon Hart, Andrew G. Nicholson, Lisa Lancaster, Helen Parfrey, Doris Rassl, William Wallace, Eleanor Valenzi, Yingze Zhang, Josyf Mychaleckyj, Amy Stockwell, Naftali Kaminski, Paul J. Wolters, Maria Molina-Molina, William A. Fahy, Fernando J. Martinez, Ian P. Hall, Martin D. Tobin, Toby M. Maher, Timothy S. Blackwell, Brian L. Yaspan, R Gisli Jenkins, Carlos Flores, Louise V Wain, Imre Noth
RationaleIdiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by limited treatment options and high mortality. Novel therapies and prognostic biomarkers are needed.ObjectiveTo identify and validate molecular determinants of IPF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b0f3a547d5e4607bcc8677ea597511
https://doi.org/10.1101/2022.05.06.22274705
https://doi.org/10.1101/2022.05.06.22274705
Autor:
Claire Cutting, Mary E. Strek, Angela L. Linderholm, Cara L. Hrusch, Anne I. Sperling, Shwu Fan Ma, Justin M. Oldham, Ayodeji Adegunsoye, Shehabaldin Alqalyoobi, Imre Noth
Publikováno v:
Am J Respir Crit Care Med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e99251e5584f172a8521d1313c86cc8
https://doi.org/10.1164/rccm.201907-1343le
https://doi.org/10.1164/rccm.201907-1343le
S65 Genome-wide association study of survival times after diagnosis of idiopathic pulmonary fibrosis
Autor:
William Wallace, Tamara Hernández-Beeftink, Justin M. Oldham, John S. Kim, Maria Molina-Molina, Yvonne J. Huang, Naftali Kaminski, Yingze Zhang, Beatriz Guillen-Guio, Nik Hirani, Ayodeji Adegunsoye, Simon P. Hart, Richard J. Allen, Angela L. Linderholm, Richard Hubbard, JM Lorenzo-Salazar, Imre Noth, Chitra Joseph, Helen Parfrey, Cathryn Lee, PL Molyneaux, V Vo, Andrew G. Nicholson, Timothy S. Blackwell, Mary E. Strek, Brian L. Yaspan, Doris Rassl, A Stockwell, Tobin, S.F. Ma, Paul J. Wolters, Carlos Flores, Mkb Whyte, RG Jenkins, Fernando J. Martinez, William A. Fahy, Janelle Vu Pugashetti, Jonathan A. Kropski, Ian P. Hall, Eleanor Valenzi, Louise V. Wain, Toby M. Maher
Publikováno v:
What’s in a genotype? Unpicking genetic links in complex disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c657148295dff7cd8d79adfd6f8f951
https://doi.org/10.1136/thorax-2021-btsabstracts.71
https://doi.org/10.1136/thorax-2021-btsabstracts.71
Autor:
Angela L. Linderholm, Justin M. Oldham, Genevieve Montas, Claude Jourdan Le Saux, Nancy K. Hills, Scott M. Turner, Kirk D. Jones, Paul J. Wolters, Prerna Kotak, Jeffrey A. Golden, B. Trinh, Darren Leong, Ying Wei, Martin Decaris, Harold A. Chapman, Jin-Woo Song, Elena Foster
Publikováno v:
N Engl J Med
EGCG and Pulmonary Fibrosis Nine patients who were scheduled to undergo lung biopsy for pulmonary fibrosis were given epigallocatechin gallate (EGCG) for 2 weeks. Levels of fibrotic markers in lung...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09f5db7da8f226fd1fd03bd51a6c98e
https://doi.org/10.1056/nejmc1915189
https://doi.org/10.1056/nejmc1915189
Publikováno v:
ERJ Open Research
ERJ open research, vol 5, iss 1
ERJ Open Research, Vol 5, Iss 1 (2019)
ERJ open research, vol 5, iss 1
ERJ Open Research, Vol 5, Iss 1 (2019)
Background Bronchial thermoplasty is a nonpharmacological, device-based treatment option for a specific population of severe asthmatic subjects, but the underlying mechanisms are largely unknown. The purpose of this study is to identify potential alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed0dfa267393a5862349ac056df7bf8
https://doi.org/10.1183/23120541.00123-2018
https://doi.org/10.1183/23120541.00123-2018