Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Angela L Meunier"'
Publikováno v:
Neurobiology of Disease, Vol 172, Iss , Pp 105816- (2022)
Early cognitive impairment in Alzheimer's disease may result in part from synaptic dysfunction caused by the accumulation oligomeric assemblies of amyloid β-protein (Aβ). Changes in hippocampal function seem critical for cognitive impairment in ear
Externí odkaz:
https://doaj.org/article/f1d6a1b9627d48f6b61e0a23fbabe965
Autor:
Andrew M. Stern, Yang Yang, Shanxue Jin, Keitaro Yamashita, Angela L. Meunier, Wen Liu, Yuqi Cai, Maria Ericsson, Lei Liu, Michel Goedert, Sjors H.W. Scheres, Dennis J. Selkoe
Publikováno v:
Neuron.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bee192f223d3da67d3b78db17c6fff2
https://doi.org/10.1016/j.neuron.2023.04.007
https://doi.org/10.1016/j.neuron.2023.04.007
Autor:
Andrew M. Stern, Dennis J. Selkoe, Yifan Dang, Lei Liu, Shan-Xue Jin, Alison C. Pietras, Trebor L. Lawton, Angela L. Meunier, Hyunchang Kwak, Beth L. Ostaszewski
Publikováno v:
Alzheimers Dement
INTRODUCTION Evidence strongly suggests that soluble oligomers of amyloid beta protein (oAβ) help initiate the pathogenic cascade of Alzheimer's disease (AD). To date, there have been no validated assays specific for detecting and quantifying oAβ i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0351c5ec76f6908272536abab26f90
https://doi.org/10.1002/alz.12457
https://doi.org/10.1002/alz.12457
Autor:
Andrew M. Stern, Yang Yang, Angela L. Meunier, Wen Liu, Yuqi Cai, Maria Ericsson, Lei Liu, Michel Goedert, Sjors H. W. Scheres, Dennis J. Selkoe
Soluble aggregates of amyloid-β (Aβ), often called oligomers, are believed to be principal drivers of neurotoxicity, spreading of pathology, and symptoms in Alzheimer’s disease (AD), but little is known about their structures in human brain. Aβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59aaab59e8edc115f7d5be7795f2eb6f
https://doi.org/10.1101/2022.10.18.512754
https://doi.org/10.1101/2022.10.18.512754
Publikováno v:
Biochemical and biophysical research communications. 611
Evidence suggests that plasma levels of tau protein phosphorylated at specific residues such as p-T181, p-T217, and p-T231 can be used as biomarkers for Alzheimer's disease (AD) diagnosis and prognosis. Accurate tools to calibrate immunoassays (calib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f10c31215c2129e1f16b6f49f0c59e
https://pubmed.ncbi.nlm.nih.gov/35483223
https://pubmed.ncbi.nlm.nih.gov/35483223
Autor:
Andrew M Stern, Lei Liu, Shanxue Jin, Wen Liu, Angela L Meunier, Maria Ericsson, Michael B Miller, Megan Batson, Tingwan Sun, Sagar Kathuria, David Reczek, Laurent Pradier, Dennis J Selkoe
Publikováno v:
Brain : a journal of neurology. 145(7)
Aqueously soluble oligomers of amyloid-β peptide may be the principal neurotoxic forms of amyloid-β in Alzheimer’s disease, initiating downstream events that include tau hyperphosphorylation, neuritic/synaptic injury, microgliosis and neuron loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37befc246416cd0360b7a28063891ef
https://pubmed.ncbi.nlm.nih.gov/35084489
https://pubmed.ncbi.nlm.nih.gov/35084489