Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Angela Koessler"'
Autor:
Anna Kobsar, Karina Koehnlechner, Philipp Klingler, Marius Niklaus, Julia Zeller-Hahn, Angela Koessler, Katja Weber, Markus Boeck, Juergen Koessler
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Storage of platelet concentrates (PC) at cold temperature (CT) is discussed as an alternative to the current standard of storage at room temperature (RT). Recently, we could show that cold-induced attenuation of inhibitory signaling is an im
Externí odkaz:
https://doaj.org/article/a37a7a2b90f941b48887f69956f8c66e
Platelet Toll-Like-Receptor-2 and -4 Mediate Different Immune-Related Responses to Bacterial Ligands
Autor:
Marius Niklaus, Philipp Klingler, Katja Weber, Angela Koessler, Sabine Kuhn, Markus Boeck, Anna Kobsar, Juergen Koessler
Publikováno v:
TH Open, Vol 06, Iss 03, Pp e156-e167 (2022)
Background Like immune cells, platelets express toll-like receptors (TLRs) on their surface membrane. TLR2 and TLR4 are able to recognize bacterial antigens and have the potential to influence hemostatic functions and classical intracellular signalin
Externí odkaz:
https://doaj.org/article/2fe63d6b7ed74d71b88708c1c347d10e
Autor:
Juergen Koessler, Philipp Klingler, Marius Niklaus, Katja Weber, Angela Koessler, Markus Boeck, Anna Kobsar
Publikováno v:
TH Open, Vol 04, Iss 03, Pp e163-e172 (2020)
Introduction Cold storage of platelets is considered to contribute to lower risk of bacterial growth and to more efficient hemostatic capacity. For the optimization of storage strategies, it is required to further elucidate the influence of refrigera
Externí odkaz:
https://doaj.org/article/7adbd640ae4f4db7aaf95b8c90808832
Autor:
Juergen Koessler, Marius Niklaus, Katja Weber, Angela Koessler, Sabine Kuhn, Markus Boeck, Anna Kobsar
Publikováno v:
TH Open, Vol 03, Iss 02, Pp e94-e102 (2019)
Abstract Background Like immune cells, platelets express the repertoire of toll-like receptors (TLR), among them TLR2 and TLR4, which are important for the recognition of bacterial patterns. Receptor-mediated functional effects in platelets have be
Externí odkaz:
https://doaj.org/article/2b83f1be579841749fcf00e8237b1dc8
Autor:
Juergen Koessler, Michaela Schwarz, Katja Weber, Julia Etzel, Angela Koessler, Markus Boeck, Anna Kobsar
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188193 (2017)
Platelets are important for effective hemostasis and considered to be involved in pathophysiological processes, e.g. in cardiovascular diseases. Platelets provided for research or for therapeutic use are frequently separated from citrated whole blood
Externí odkaz:
https://doaj.org/article/ea0bbf1519fe4f2cad87496b1fb9c3d4
Autor:
Juergen Koessler, Stephanie Hermann, Katja Weber, Angela Koessler, Sabine Kuhn, Markus Boeck, Anna Kobsar
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147370 (2016)
BACKGROUND:Washing of platelets is an important procedure commonly used for experimental studies, e.g. in cardiovascular research. As a known phenomenon, responsiveness to adenosine diphosphate (ADP) is reduced in washed platelets, although underlyin
Externí odkaz:
https://doaj.org/article/e07b746bcfa04b6caae252954f93580f
Autor:
Sabine Kuhn, Marius Niklaus, Katja Weber, Angela Koessler, Markus Boeck, Juergen Koessler, Anna Kobsar
Publikováno v:
TH Open: Companion Journal to Thrombosis and Haemostasis
TH Open, Vol 03, Iss 02, Pp e94-e102 (2019)
TH Open, Vol 03, Iss 02, Pp e94-e102 (2019)
Background Like immune cells, platelets express the repertoire of toll-like receptors (TLR), among them TLR2 and TLR4, which are important for the recognition of bacterial patterns. Receptor-mediated functional effects in platelets have been investig
Autor:
Anna Kobsar, Katja Weber, Angela Koessler, Markus Boeck, Juergen Koessler, Valerie-Noelle Trulley, Andrea Bosch
Publikováno v:
Thrombosis Research. 168:40-46
Introduction Adenosine diphosphate (ADP) as physiological activator of human platelets mediates its effects via three purinergic receptors: P2Y1, P2Y12 and P2X1. The inhibition of P2Y12 is used pharmacologically to suppress aggregation underlining th
Autor:
Angela Koessler, Juergen Koessler, Philipp Klingler, Katja Weber, Anna Kobsar, Marius Niklaus, Markus Boeck
Publikováno v:
Vascular Pharmacology. 138:106830
Introduction: Although platelets contain a full proteasome system, its role in platelet function is not completely understood yet. Since the proteasome system may be involved in time-delayed processes, platelet responsiveness was investigated after l
Autor:
Angela Koessler, Juergen Koessler, Markus Boeck, Philipp Klingler, Katja Weber, Marius Niklaus, Anna Kobsar
Publikováno v:
Cellular Signalling. 76:109817
In addition to haemostasis, platelets play an essential role in mechanisms of inflammation and in immunological reactions. Platelets express various toll-like receptors (TLR) on their surface, among them TLR2 and TLR4, which are important for the rec