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pro vyhledávání: '"Angela Kj Park"'
Publikováno v:
Biochemical and Biophysical Research Communications. 503:710-714
The emergence of the T790M gatekeeper mutation in the Epidermal Growth Factor Receptor (EGFR) gene is an important mechanism that can lead to the acquired resistance to EGFR-targeted tyrosine kinase inhibitors such as erlotinib or gefitinib. These dr
Publikováno v:
Cancer Research. 79:1281-1281
The emergence of the T790M gatekeeper mutation in the Epidermal Growth Factor Receptor (EGFR) gene is an important mechanism that can lead to the acquired resistance to EGFR-targeted tyrosine kinase inhibitors used in a subset of non-small cell lung
Autor:
Kyoung-Mee Kim, Yoon-La Choi, J. O. Park, Angela Kj Park, Keunchil Park, Meraj Aziz, Ahye Cho, Nayoung K.D. Kim, Joshua M. Francis, Joon Seol Bae, Hongwei Holly Yin, Soomin Ahn, Michelle Kassner, Myung-Ju Ahn, Hideo Watanabe, Jeonghee Cho, Je-Gun Joung, Woong-Yang Park
Publikováno v:
Cancer Research. 76:2931-2931
Therapies targeting the tyrosine kinase activity of Epidermal Growth Factor Receptor (EGFR) have been proven to be effective in treating a subset of non-small cell lung cancer (NSCLC) patients harboring activating EGFR mutations. Inevitably these pat