Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Angela K, Walker"'
Autor:
Qiang-Qiang Xia, Angela K Walker, Chenghui Song, Jing Wang, Anju Singh, James A Mobley, Zhong X Xuan, Jeffrey D Singer, Craig M Powell
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0283299 (2023)
Autism Spectrum Disorder (ASD) is a developmental disorder in which children display repetitive behavior, restricted range of interests, and atypical social interaction and communication. CUL3, coding for a Cullin family scaffold protein mediating as
Externí odkaz:
https://doaj.org/article/3822b5b797b9457ab8bef3f0813fc6a5
Autor:
Weihua Zhou, Yangyang Yao, Andrew J. Scott, Kari Wilder-Romans, Joseph J. Dresser, Christian K. Werner, Hanshi Sun, Drew Pratt, Peter Sajjakulnukit, Shuang G. Zhao, Mary Davis, Barbara S. Nelson, Christopher J. Halbrook, Li Zhang, Francesco Gatto, Yoshie Umemura, Angela K. Walker, Maureen Kachman, Jann N. Sarkaria, Jianping Xiong, Meredith A. Morgan, Alnawaz Rehemtualla, Maria G. Castro, Pedro Lowenstein, Sriram Chandrasekaran, Theodore S. Lawrence, Costas A. Lyssiotis, Daniel R. Wahl
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Targeting genotype-independent abnormalities may overcome therapy resistance in glioblastoma despite intratumoral genomic heterogeneity. Here, the authors show that glioblastoma radiation resistance is promoted by purine metabolism and can be overcom
Externí odkaz:
https://doaj.org/article/1b59daa1bcd04cf3a9e4d552dbc954ba
Autor:
Cemre Celen, Jen-Chieh Chuang, Xin Luo, Nadine Nijem, Angela K Walker, Fei Chen, Shuyuan Zhang, Andrew S Chung, Liem H Nguyen, Ibrahim Nassour, Albert Budhipramono, Xuxu Sun, Levinus A Bok, Meriel McEntagart, Evelien F Gevers, Shari G Birnbaum, Amelia J Eisch, Craig M Powell, Woo-Ping Ge, Gijs WE Santen, Maria Chahrour, Hao Zhu
Publikováno v:
eLife, Vol 6 (2017)
Sequencing studies have implicated haploinsufficiency of ARID1B, a SWI/SNF chromatin-remodeling subunit, in short stature (Yu et al., 2015), autism spectrum disorder (O'Roak et al., 2012), intellectual disability (Deciphering Developmental Disorders
Externí odkaz:
https://doaj.org/article/ed40f28284084f4c913b487a3f35a670
Autor:
Angela K Walker, Won-Mee Park, Jen-Chieh Chuang, Mario Perello, Ichiro Sakata, Sherri Osborne-Lawrence, Jeffrey M Zigman
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60276 (2013)
Histamine is a potent biogenic amine that mediates numerous physiological processes throughout the body, including digestion, sleep, and immunity. It is synthesized by gastric enterochromaffin-like cells, a specific set of hypothalamic neurons, as we
Externí odkaz:
https://doaj.org/article/3226b9a5e7bd4dbeb1162d7bd5cfea23
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64882 (2013)
Ghrelin is an orexigenic peptide hormone produced mainly by a distinct group of dispersed endocrine cells located within the gastric oxyntic mucosa. Besides secreted gene products derived from the preproghrelin gene, which include acyl-ghrelin, desac
Externí odkaz:
https://doaj.org/article/e8f85e95025e4b30910fd0915903dfa1
Autor:
Drew Pratt, Mary A. Davis, Theodore S. Lawrence, Hanshi Sun, Christian K. Werner, Li Zhang, Yoshie Umemura, Joseph Dresser, Andrew J. Scott, Daniel R. Wahl, Barbara S. Nelson, Maureen Kachman, Sriram Chandrasekaran, Weihua Zhou, Jann N. Sarkaria, Shuang G. Zhao, Alnawaz Rehemtualla, Yangyang Yao, Angela K. Walker, Jianping Xiong, Pedro R. Lowenstein, Christopher J. Halbrook, Costas A. Lyssiotis, Meredith A. Morgan, Francesco Gatto, Peter Sajjakulnukit, Kari Wilder-Romans, Maria G. Castro
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Intratumoral genomic heterogeneity in glioblastoma (GBM) is a barrier to overcoming therapy resistance. Treatments that are effective independent of genotype are urgently needed. By correlating intracellular metabolite levels with radiation resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f892b9ac49f35ce399ac6604accc487
https://doi.org/10.1038/s41467-020-17512-x
https://doi.org/10.1038/s41467-020-17512-x
Autor:
Jason P. Lerch, Amelia J. Eisch, Haley E. Speed, Roopashri Holehonnur, Craig M. Powell, Genevieve Konopka, Felipe Espinosa, Summer B. Thyme, Zhong X. Xuan, Angela K. Walker, Noriyoshi Usui, Jacob Ellegood, Shunan Liu, Christine Ochoa Escamilla, Alexander F. Schier, Irina Filonova, Dorian B. Mendoza, Isabel A. López-García
Publikováno v:
Nature. 551:227-231
Copy-number variants of chromosome 16 region 16p11.2 are linked to neuropsychiatric disorders1–6 and are among the most prevalent in autism spectrum disorders1,2,7. Of many 16p11.2 genes, Kctd13 has been implicated as a major driver of neurodevelop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5454e1d25773901fc0c4ac377546b174
https://doi.org/10.1038/nature24470
https://doi.org/10.1038/nature24470
Autor:
Thomas G. Harris, Angela K. Walker
Publikováno v:
Foot and ankle clinics. 24(4)
Two theories exist in the development of central or transfer metatarsalgia. First, as the severity of hallux valgus increases, there is mechanical overload of the second metatarsal. Second, increased relative lesser metatarsal length is thought to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef957825c420bd4cfb59641cb3d87be5
https://pubmed.ncbi.nlm.nih.gov/31653368
https://pubmed.ncbi.nlm.nih.gov/31653368
Autor:
Daniel Wahl, Luis Correa, Weihua Zhou, Andrew C. Scott, Joseph Dresser, Sriram Chandrasekaran, Drew Pratt, Mary A. Davis, Maureen Kachman, Barbara S. Nelson, Francesco Gatto, Jianping Xiong, Angela K. Walker, Li Zhang, Yoshie Umemura, Neil K. Jairath, Alnawaz Rehemtulla, Shuang Zaho, Pedro R. Lowenstein, Sudharsan Srinivasan, Christopher J. Halbrook, Jann N. Sarkaria, Hanshi Sun, Yangyang Yao, Nathan Qi, Costas A. Lyssiotis, Meredith A. Morgan, Peter Sajjakulnukit, Theodore Lawrence, Kari Wilder-Romans, Maria G. Castro, Christian K. Werner
Publikováno v:
Neuro-oncology Advances
Intratumoral genomic heterogeneity in glioblastoma (GBM) is a barrier to overcoming radiation (RT) resistance. To discover genotype-independent mediators of RT resistance, we correlated RT resistance with the concentration of approximately 700 metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd80a1de2d16c10b3d90c8f9236e1589
https://doi.org/10.1093/noajnl/vdab024.046
https://doi.org/10.1093/noajnl/vdab024.046
Autor:
Francisca Ahn, Wellington Z. Amaral, David H. Beddow, Nathan A. DeCarolis, Benjamin P C Chen, Sarah E. Bulin, Junie A. Leblanc, Mara G. Cole, Cody W. Whoolery, Phillip D. Rivera, K. Lyles Clark, Devon R. Richardson, Amelia J. Eisch, Ryan P. Reynolds, Sanghee Yun, Melanie J. Lucero, Angela K. Walker, Shibani Mukherjee, Shichuan Zhang, Hung Ying Shih
Astronauts traveling to Mars will be exposed to chronic low doses of galactic cosmic space radiation, which contains highly charged, high-energy (HZE) particles. 56Fe-HZE-particle exposure decreases hippocampal dentate gyrus (DG) neurogenesis and dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef923d464bb33fcf1e951151b8371803
https://europepmc.org/articles/PMC5901735/
https://europepmc.org/articles/PMC5901735/
