Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Angela J. Glading"'
Autor:
Harsha Swamy, Angela J. Glading
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Recent advances have steadily increased the number of proteins and pathways known to be involved in the development of cerebral cavernous malformation (CCM). Our ability to synthesize this information into a cohesive and accurate signaling model is l
Externí odkaz:
https://doaj.org/article/1e9480b6a7034e51a0a28496e885a621
Autor:
Luca Goitre, Peter V. DiStefano, Andrea Moglia, Nicholas Nobiletti, Eva Baldini, Lorenza Trabalzini, Julie Keubel, Eliana Trapani, Vladimir V. Shuvaev, Vladimir R. Muzykantov, Ingrid H. Sarelius, Saverio Francesco Retta, Angela J. Glading
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The intracellular scaffold KRIT1/CCM1 is an established regulator of vascular barrier function. Loss of KRIT1 leads to decreased microvessel barrier function and to the development of the vascular disorder Cerebral Cavernous Malformation (CC
Externí odkaz:
https://doaj.org/article/6fc3adc7ae70457492848b492ff196e1
Publikováno v:
The FEBS Journal. 290:1078-1095
Loss of Krev interaction-trapped-1 (KRIT1) expression leads to the development of cerebral cavernous malformations (CCM), a disease in which abnormal blood vessel formation compromises the structure and function of the blood-brain barrier. The role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f043e7bca9dd164f9e911695521be7
https://doi.org/10.1111/febs.16627
https://doi.org/10.1111/febs.16627
Autor:
Angela J, Glading
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2152
Vascular permeability is a major function of the microvasculature that is regulated by multiple factors including blood pressure, blood viscosity, and endothelial barrier function. Intravital microscopy has been used to directly assess vascular perme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77b72a223dc0e92b16248c2cadfeb2ec
https://pubmed.ncbi.nlm.nih.gov/32524567
https://pubmed.ncbi.nlm.nih.gov/32524567
Autor:
Nicholas, Nobiletti, Angela J, Glading
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2152
Cerebral cavernous malformation (CCM) is driven by changes in the cerebral microvascular endothelial cell population. Mouse models of CCM have successfully recapitulated the disease in vivo; however, dissection of the disease pathogenesis and molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4402e9710e8708a43b585e9b6309eb4
https://pubmed.ncbi.nlm.nih.gov/32524558
https://pubmed.ncbi.nlm.nih.gov/32524558
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162338 (2016)
The phosphoinositide-specific phospholipase C, PLCε, is a unique signaling protein with known roles in regulating cardiac myocyte growth, astrocyte inflammatory signaling, and tumor formation. PLCε is also expressed in endothelial cells, however it
Externí odkaz:
https://doaj.org/article/d9ef0ba422754e9dbade798d6cff4b29