Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Angela H Guo"'
Autor:
Joseph S Harrison, Evan M Cornett, Dennis Goldfarb, Paul A DaRosa, Zimeng M Li, Feng Yan, Bradley M Dickson, Angela H Guo, Daniel V Cantu, Lilia Kaustov, Peter J Brown, Cheryl H Arrowsmith, Dorothy A Erie, Michael B Major, Rachel E Klevit, Krzysztof Krajewski, Brian Kuhlman, Brian D Strahl, Scott B Rothbart
Publikováno v:
eLife, Vol 5 (2016)
The epigenetic inheritance of DNA methylation requires UHRF1, a histone- and DNA-binding RING E3 ubiquitin ligase that recruits DNMT1 to sites of newly replicated DNA through ubiquitylation of histone H3. UHRF1 binds DNA with selectivity towards hemi
Externí odkaz:
https://doaj.org/article/a0c4f588bf4d4946bb43d1fe3709ba4c
Autor:
Angela H. Guo, Rachael Baliira, Mary E. Skinner, Surinder Kumar, Anthony Andren, Li Zhang, Robert S. Goldsmith, Shaday Michan, Norma J. Davis, Merissa W. Maccani, Sharlene M. Day, David A. Sinclair, Matthew J. Brody, Costas A. Lyssiotis, Adam B. Stein, David B. Lombard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Heart failure (HF) is the inability of the heart to pump blood sufficiently to meet the metabolic demands of the body. HF with reduced systolic function is characterized by cardiac hypertrophy, ventricular fibrosis and remodeling, and decrea
Externí odkaz:
https://doaj.org/article/f2220b371be640c7a9e5d76ededdbcf9
Autor:
Forest H. Andrews, Qiong Tong, Kelly D. Sullivan, Evan M. Cornett, Yi Zhang, Muzaffar Ali, JaeWoo Ahn, Ahway Pandey, Angela H. Guo, Brian D. Strahl, James C. Costello, Joaquin M. Espinosa, Scott B. Rothbart, Tatiana G. Kutateladze
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3195-3207 (2016)
MORC3 is linked to inflammatory myopathies and cancer; however, the precise role of MORC3 in normal cell physiology and disease remains poorly understood. Here, we present detailed genetic, biochemical, and structural analyses of MORC3. We demonstrat
Externí odkaz:
https://doaj.org/article/29a2fe82f94d43ca89253c6ee5084b46
Publikováno v:
Curr Opin Toxicol
Cadmium (Cd) is a widespread toxic pollutant that affects millions of individuals worldwide. Cd exposure in humans occurs primarily through consumption of contaminated food and water, cigarette smoking, and industrial applications. The kidney proxima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ddfbc2c00c5b55baeeb97b1ef06e0f
https://europepmc.org/articles/PMC10168606/
https://europepmc.org/articles/PMC10168606/
Publikováno v:
Cancer Research. 83:4718-4718
Like the chromatin immunoprecipitation (ChIP) assay, Cleavage Under Targets & Release Using Nuclease (CUT&RUN) is a powerful and versatile technique used for probing protein-DNA interactions within the natural chromatin context of the cell. The CUT&R
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports 10 (2020)
Scientific Reports, 10
Scientific Reports
Scientific Reports 10 (2020)
Scientific Reports, 10
Scientific Reports
Succinylation is a novel post-translational modification identified on many proteins and is involved in multiple biological processes. Succinylation levels are dynamically regulated, balanced by succinylation and desuccinylation processes, and are cl
Autor:
Mary E. Skinner, Adam B. Stein, David A. Sinclair, Anthony Andren, Maccani Mw, Angela H. Guo, David B. Lombard, Sharleen Day, Long Zhang, Costas A. Lyssiotis, Davis Nj, Michan S, Baliira Rk, Surinder Kumar
Heart failure (HF) is defined as an inability of the heart to pump blood adequately to meet the body’s metabolic demands. HF with reduced systolic function is characterized by cardiac hypertrophy, ventricular fibrosis and remodeling, and decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c312b2dcd2eba6b1efa0d2ea8e3ec38a
https://doi.org/10.1101/2021.06.15.448619
https://doi.org/10.1101/2021.06.15.448619
Autor:
Miguel Rivera, Richard A. Sturm, Sophie Trefely, Peter Sajjakulnukit, Richard A. Scolyer, James S. Wilmott, Keith-Allen Melong, Sowmya Iyer, Costas A. Lyssiotis, Ho-Joon Lee, Min Wang, Andrei L. Osterman, Angela H. Guo, Surinder Kumar, Aleodor A. Andea, Ahmed Mostafa, H. Peter Soyer, Michelle Azar, Lauren Bringman-Rodenbarger, William Giblin, David B. Lombard, Zaneta Nikolovska-Coleska, Li Zhang, Douglas R. Fullen, Ahmed S.A. Mady, David Scott, Sriram Chandrasekaran, Mitchell S. Stark, Nathaniel W. Snyder, Carolina H Chung, Alexander C. Monovich, Marcus Bosenberg, Erika L. Varner, Antonia L. Pritchard, Namrata S Kadambi, Mary E. Skinner, Monique Verhaegen
Publikováno v:
J Clin Invest
Cutaneous melanoma remains the most lethal skin cancer, and ranks third among all malignancies in terms of years of life lost. Despite the advent of immune checkpoint and targeted therapies, only roughly half of patients with advanced melanoma achiev
Autor:
Christi M. Gendron, Richard A. Miller, Thomas Girke, Zaneta Nikolovska-Coleska, Tsui Ting Ching, Weiqiao Ding, William J. Kohler, David B. Lombard, Melissa Han, Feng Yung Wang, Ao Lin Hsu, Yuzhu Duan, Angela H. Guo, Scott D. Pletcher, Tuhin Subhra Chakraborty, Yang Lyu
Publikováno v:
Science Advances
High-throughput screening identifies small molecules that promote cellular stress resistance.
Aging is the dominant risk factor for most chronic diseases. Development of antiaging interventions offers the promise of preventing many such illnesse
Aging is the dominant risk factor for most chronic diseases. Development of antiaging interventions offers the promise of preventing many such illnesse
Autor:
Yang Lyu, Scott D. Pletcher, David B. Lombard, Melissa Han, William Kohler, Christi M. Gendron, Zaneta Nikolovska-Coleska, Ao Lin Hsu, Xiaofang Shi, Thomas Girke, Xinna Li, Yuzhu Duan, Angela H. Guo, Weiqiao Ding, Richard A. Miller
Biological aging is the dominant risk factor for most chronic diseases. Development of anti-aging interventions offers the promise of preventing many such illnesses simultaneously. Cellular stress resistance is an evolutionarily conserved feature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a660c1018dc9af99a781c50f229b09c