Dietary non-starch polysaccharides impair immunity to enteric nematode infection

Autor: Angela H. Valente, Karen M. R. Jensen, Laura J. Myhill, Ling Zhu, Caroline M. J. Mentzel, Lukasz Krych, Henrik T. Simonsen, Josue L. Castro-Mejía, Alex Gobbi, Knud Erik Bach Knudsen, Dennis S. Nielsen, Stig M. Thamsborg, Andrew R. Williams

Publikováno v: BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)

Abstract Background The influence of diet on immune function and resistance to enteric infection and disease is becoming ever more established. Highly processed, refined diets can lead to inflammation and gut microbiome dysbiosis, whilst health-promo

Externí odkaz: https://doaj.org/article/424ae6d16692466fa29bd877b07a6eb4

Anti-protozoal activity and metabolomic analyses of Cichorium intybus L. against Trypanosoma cruzi

Autor: Miguel Peña-Espinoza, Yeambell Romero-Uzqueda, Angela H. Valente, Matthew de Roode, Henrik T. Simonsen, Stig M. Thamsborg, Andrew R. Williams, Rodrigo López-Muñoz

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance, Vol 20, Iss , Pp 43-53 (2022)

Chagas disease, caused by the protozoa Trypanosoma cruzi, is a potentially life-threatening parasitic zoonosis infecting 6–7 million people worldwide, mainly in Latin America. Due to the limited numbers of drugs available against this neglected dis

Externí odkaz: https://doaj.org/article/cb66f6511bf248cba1e8d950b0f98cfd

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review

Autor: Miguel Peña-Espinoza, Angela H. Valente, Stig M. Thamsborg, Henrik T. Simonsen, Ulrik Boas, Heidi L. Enemark, Rodrigo López-Muñoz, Andrew R. Williams

Publikováno v: Parasites & Vectors, Vol 11, Iss 1, Pp 1-14 (2018)

Abstract Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the

Externí odkaz: https://doaj.org/article/fa427d4a0bbc48b495c2a3080c0a6235

Anthelmintic and metabolomic analyses of chicory (Cichorium intybus) identify an industrial by-product with potent in vitro antinematodal activity

Autor: Miguel, Peña-Espinoza, Angela H, Valente, Louis, Bornancin, Henrik T, Simonsen, Stig M, Thamsborg, Andrew R, Williams, Rodrigo, López-Muñoz

Publikováno v: ORCID
Microsoft Academic Graph

Chicory (Cichorium intybus) is a bioactive forage rich in sesquiterpene lactones (SLs) with reported in vitro and in vivo anthelmintic activity in livestock. However, the on-farm adoption of chicory as an anthelmintic crop is limited and may be facil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b6ead7fa87e59ac654e6dab03ef445
https://orgprints.org/id/eprint/42909/

Anti-protozoal activity of extracts from chicory (Cichorium intybus) against Cryptosporidium parvum in cell culture

Autor: Andrew R. Williams, Angela H. Valente, Heidi L. Enemark, Henrik Toft Simonsen, Ian David Woolsey, Stig Milan Thamsborg

Publikováno v: Woolsey, I D, Valente, A H, Williams, A R, Thamsborg, S M, Simonsen, H T & Enemark, H L 2019, ' Anti-protozoal activity of extracts from chicory ( Cichorium intybus ) against Cryptosporidium parvum in cell culture ', Scientific Reports, vol. 9, no. 1, 20414 . https://doi.org/10.1038/s41598-019-56619-0
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports

Cryptosporidium spp. are responsible for severe public health problems and livestock production losses. Treatment options are limited to only one drug available for human and bovine cryptosporidiosis, respectively, and both drugs exhibit only partial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28e420e8e3c9b11291e38fe06dd3219
https://orbit.dtu.dk/en/publications/d2fa4189-893b-4a64-b295-0318571e8984